Browsing by Author "Díez Pérez, Adolfo"

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  • Pérez-Sáez, María José; Prieto-Alhambra, Daniel; Díez Pérez, Adolfo; Pascual Santos, Julio (Elsevier, 2017)
    Bone disease related to chronic kidney disease and, particularly, to kidney transplant patients is a common cause or morbidity and mortality, especially due to a higher risk of osteoporotic fractures. Despite the fact that ...
  • Pineda-Moncusí, Marta; Servitja Tormo, Sonia; Casamayor, Guillem; Cos, Maria Lourdes; Rial, Abora; Rodriguez-Morera, Jaime; Tusquets, Ignasi; Díez Pérez, Adolfo; Garcia Giralt, Natàlia; Nogués Solan, Francesc Xavier (Elsevier, 2018)
    Breast cancer patients treated with aromatase inhibitors (AIs) experience increased bone loss during their treatment. However, there is little information about bone mineral density (BMD) after completing AI-treatment. The ...
  • Rudäng, R.; Zoulaki, M.; Sundh, D.; Brisby, H.; Díez Pérez, Adolfo; Johansson, L.; Mellström, D.; Darelid, A.; Lorentzon, M. (Springer Verlag, 2016)
    Reference point indentation is a novel method to assess bone material strength index (BMSi) in vivo. We found that BMSi at the mid-tibia was weakly associated with spine and hip areal bone mineral density but not with ...
  • Garcia Giralt, Natàlia; Ugarte Corbalán, Laura de, 1988-; Yoskovitz, Guy; Güerri Fernández, Roberto; Grinberg, Daniel; Nogués Solán, Xavier; Mellibovsky, Leonardo; Balcells, Susana; Díez Pérez, Adolfo (Sociedad Española de Investigación Ósea y del Metabolismo Mineral (SEIOMM), 2016)
    Objetivos: Identificar microRNAs (miRNAs) diferencialmente expresados en muestras óseas con fractura osteoporótica respecto a huesos sanos. Material y métodos: Se extrajo RNA total a partir de hueso trabecular fresco del ...
  • Rodríguez Sanz, Maria, 1984-; Prieto-Alhambra, Daniel; Servitja Tormo, Sonia; Garcia Giralt, Natàlia; Garrigos, L.; Albanell Mestres, Joan; Martinez-García, Maria; González, I.; Martos, Tamara; Díez Pérez, Adolfo; Tusquets Trias de Bes, Ignacio; Nogués Solán, Xavier (Sociedad Española de Investigación Ósea y del Metabolismo Mineral, 2015)
    Objetivos: El objetivo del estudio fue analizar los cambios en la densidad mineral ósea (DMO) a lo largo del tratamiento con inhibidores de aromatasa (IA) en la práctica clínica y evaluar la asociación entre el gen CYP11A1 ...
  • Ugarte Corbalán, Laura de, 1988-; Serra-Vinardell, Jenny; Nonell Mazelón, Lara; Balcells, Susana; Arnal, Magdalena; Nogués Solan, Francesc Xavier; Mellibovsky, Leonardo; Grinberg, Daniel; Díez Pérez, Adolfo; Garcia Giralt, Natàlia (Springer, 2018)
    Bone tissue is composed of several cell types, which express their own microRNAs (miRNAs) that will play a role in cell function. The set of total miRNAs expressed in all cell types configures the specific signature of the ...
  • Roca Ayats, Neus; Ng, Pei Ying; García-Giralt, Natalia; Falcó-Mascaró, Maite; Cozar, Mónica; Abril Ferrando, Josep Francesc; Quesada-Gómez, J.M.; Prieto-Alhambra, Daniel; Nogués Solan, Francesc Xavier; Dunford, James E.; Russell, R. Graham; Baron, Roland; Grinberg, Daniel; Balcells, Susana; Díez Pérez, Adolfo (Wiley, 2018)
    Atypical femoral fractures (AFFs) are a rare but potentially devastating event, often but not always linked to bisphosphonate (BP) therapy. The pathogenic mechanisms underlying AFFs remain obscure, and there are no tests ...
  • Prieto-Alhambra, Daniel; Nogués Solán, Xavier; Díez Pérez, Adolfo (SpringerOpen, 2018)
    We have characterised 997 hip fracture patients from a representative 45 Spanish hospitals, and followed them up prospectively for up to 4 months. Despite suboptimal surgical delays (average 59.1 hours), in-hospital mortality ...
  • Losada-Grande, Eladio; Hawley, Samuel; Soldevila, Berta; Martinez-Laguna, Daniel; Nogués Solan, Francesc Xavier; Díez Pérez, Adolfo; Puig-Domingo, Manel; Mauricio, Dídac; Prieto-Alhambra, Daniel (Nature Publishing Group, 2017)
    Despite normal to high bone mineral density, patients with type 2 diabetes (T2DM) have an increased fracture risk. T2DM medications could partially account for this excess risk. The aim of this study was to assess the ...
  • Pérez-Saez , María José; Herrera, Sabina; Prieto-Alhambra, Daniel; Vilaplana, Laia; Nogués Solán, Xavier; Vera, María; Redondo Pachón, María Dolores; Mir Fontana, M. Luisa; Güerri Fernández, Roberto; Crespo Barrio, Marta; Díez Pérez, Adolfo; Pascual Santos, Julio (Elsevier, 2018)
    Soon after kidney transplant (KT), a decrease in parathormone and bone mineral density (BMD) occur, but little is known on the impact of KT on novel bone quality parameters including trabecular bone score (TBS) and bone ...
  • Ugarte Corbalán, Laura de, 1988-; Yoskovitz, Guy; Balcells, Susana; Güerri Fernández, Roberto; Martinez-Diaz, Santos; Mellibovsky, Leonardo; Urreizti, Roser; Nogués Solan, Francesc Xavier; Grinberg, Daniel; Garcia Giralt, Natàlia; Díez Pérez, Adolfo (BioMed Central, 2015)
    BACKGROUND: MicroRNAs (miRNAs) are important regulators of gene expression, with documented roles in bone metabolism and osteoporosis, suggesting potential therapeutic targets. Our aim was to identify miRNAs differentially ...
  • Shabestari, Maziar; Eriksen, Erik Fink; Paschalis, Eleftherios P.; Roschger, Paul; Gamsjaeger, Sonja; Klaushofer, Klaus; Berzlanovich, Andrea; Nogués Solan, Francesc Xavier; Puig Verdié, Luís; Díez Pérez, Adolfo (Elsevier, 2017)
    Long-term antiresorptives use has been linked to atypical subtrochanteric and diaphyseal femoral fractures (AFF), the pathogenesis of which is still unknown. In the present case report we present the results of analysis ...
  • Ugarte Corbalán, Laura de, 1988-; Balcells, Susana; Nogués Solán, Francesc Xavier; Grinberg, Daniel; Díez Pérez, Adolfo; Garcia Giralt, Natàlia (Public Library of Science (PLoS), 2018)
    MicroRNAs (miRNAs) are important regulators of many cellular processes, including the differentiation and activity of osteoblasts, and therefore, of bone turnover. MiR-320a is overexpressed in osteoporotic bone tissue but ...
  • Ugarte Corbalán, Laura de, 1988-; Caro-Molina, Enrique; Rodríguez Sanz, Maria, 1984-; Nogués Solan, Francesc Xavier; Garcia Giralt, Natàlia; Díez Pérez, Adolfo (Nature Publishing Group, 2017)
    Biogenesis and function of microRNAs can be influenced by genetic variants in the pri-miRNA sequences leading to phenotypic variability. This study aims to identify single nucleotide polymorphisms (SNPs) affecting the ...
  • Rodríguez Sanz, Maria, 1984-; Pineda-Moncusí, Marta; Servitja Tormo, Sonia; Garcia Giralt, Natàlia; Martos, Tamara; Tusquets Trias de Bes, Ignacio; Martínez-García, Maria; Rodriguez-Morera, Jaime; Díez Pérez, Adolfo; Albanell Mestres, Joan; Nogués Solan, Francesc Xavier (Elsevier, 2016)
    INTRODUCTION: Patients with breast cancer under aromatase inhibitor (AI) treatment often develop osteoporosis and their average bone loss rate is twice that of natural reduction during menopause, increasing fracture risk. ...
  • Lerma-Chippirraz, Elisabet; Güerri Fernández, Roberto; Villar García, Judit; González Mena, Alicia; Guelar Grinberg, Ana; Montero, M.; Sorli Redó, M. Luisa; Calzado, Sonia; Horcajada Gallego, Juan Pablo; Díez Pérez, Adolfo; Knobel Freud, Hernando (Hindawi, 2016)
    Hypovitaminosis D and secondary hyperparathyroidism are frequent among HIV-infected patients. As there are no data about the best supplementation therapy both in treatment and in maintenance, we conducted an observational ...
  • Pineda-Moncusí, Marta; García-Pérez, Miguel Angel; Rial, Abora; Casamayor, Guillem; Cos, Maria Lourdes; Servitja Tormo, Sonia; Tusquets, Ignasi; Díez Pérez, Adolfo; Cano, Antonio; Garcia Giralt, Natàlia; Nogués Solan, Francesc Xavier (Elsevier, 2018)
    To evaluate the vitamin D status of postmenopausal women with early estrogen-receptor-positive breast cancer and to compare it with that of healthy postmenopausal women from the same Mediterranean region. STUDY DESIGN AND ...