Browsing by Author "Cuscó Pons, Pol, 1987-"

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  • Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions
    Navas Pérez, Enrique; Cuscó Pons, Pol, 1987-; García Fernàndez, Jordi (BioMed Central, 2020)
    Background: One of the most unusual sources of phylogenetically restricted genes is the molecular domestication of transposable elements into a host genome as functional genes. Although these kinds of events are sometimes ...
  • Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation
    Vilarrasa-Blasi, Roser; Soler-Vila, Paula; Verdaguer-Dot, Núria; Russiñol, Núria; Di Stefano, Marco; Chapaprieta, Vicente; Clot, Guillem; Farabella, Irene; Cuscó Pons, Pol, 1987-; Kulis, Marta; Agirre, Xabier; Prosper, Felipe; Beekman, Renée; Beà, Sílvia; Colomer Pujol, Dolors; Stunnenberg, Hendrik G.; Gut, Ivo Glynne; Campo, Elias; Marti-Renom, Marc A.; Martin-Subero, José Ignacio (Nature Research, 2021)
    To investigate the three-dimensional (3D) genome architecture across normal B cell differentiation and in neoplastic cells from different subtypes of chronic lymphocytic leukemia and mantle cell lymphoma patients, here we ...
  • Hierarchical chromatin organization detected by TADpole
    Soler-Vila, Paula; Cuscó Pons, Pol, 1987-; Farabella, Irene; Di Stefano, Marco; Martí Renom, Marc A. (Oxford University Press, 2020)
    The rapid development of Chromosome Conformation Capture (3C-based techniques), as well as imaging together with bioinformatics analyses, has been fundamental for unveiling that chromosomes are organized into the so-called ...
  • Mass spectrometry identification of biomarkers in extracellular vesicles from plasmodium vivax liver hypnozoite infections
    Gualdrón-López, Melisa; Díaz Varela, Míriam; Aparici-Herraiz, Iris; Cuscó Pons, Pol, 1987-; González, Juan Ramón; Borràs, Eva; Sabidó Aguadé, Eduard, 1981-; Fernandez-Becerra, Carmen; del Portillo, Hernando A. (Elsevier, 2022)
    Latent liver stages termed hypnozoites cause relapsing Plasmodium vivax malaria infection and represent a major obstacle in the goal of malaria elimination. Hypnozoites are clinically undetectable, and presently, there are ...
  • Starcode: sequence clustering based on all-pairs search
    Zorita, Eduard; Cuscó Pons, Pol, 1987-; Filion, Guillaume (Oxford University Press, 2015)
    Motivation: The increasing throughput of sequencing technologies offers new applications and challenges for computational biology. In many of those applications, sequencing errors need to be/ncorrected. This is particularly ...
  • Zerone: a ChIP-seq discretizer for multiple replicates with built-in quality control
    Cuscó Pons, Pol, 1987-; Filion, Guillaume (Oxford University Press, 2016)
    Motivation: Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) is the standard method to investigate chromatin protein composition. As the number of community-available ChIP-seq profiles ...

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