Browsing by Author "Curto, Josué"

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  • Vinyoles, Meritxell; Valle Pérez, Beatriz del; Curto, Josué; Padilla, Mary; Villarroel, Aida; Yang, J.Y.; García de Herreros, Antonio; Duñach, Mireia (Springer Nature, 2017)
    Canonical Wnt signaling induces the stabilization of β-catenin, its translocation to the nucleus and the activation of target promoters. This pathway is initiated by the binding of Wnt ligands to the Frizzled receptor, the ...
  • Curto, Josué; Valle Pérez, Beatriz del; Villarroel, Aida; Fuertes, Guillem; Vinyoles, Meritxell; Peña, Raúl; García de Herreros, Antonio; Duñach, Mireia (Wiley, 2018)
    Canonical and noncanonical Wnt pathways share some common elements but differ in the responses they evoke. Similar to Wnt ligands acting through the canonical pathway, Wnts that activate the noncanonical signaling, such ...
  • Vinyoles, Meritxell; Valle Pérez, Beatriz del; Curto, Josué; Viñas Castells, Rosa, 1985-; Alba Castellón, Lorena, 1984-; García de Herreros, Antonio; Duñach, Mireia (Elsevier, 2014)
    The Wnt canonical ligands elicit the activation of β-catenin transcriptional activity, a response dependent on, but not limited to, β-catenin stabilization through the inhibition of GSK3 activity. Two mechanisms have been ...
  • Alba-Castellón, Lorena; Batlle, Raquel; Francí, Clara; Fernández Aceñero, María Jesús; Mazzolini, Rocco; Peña, Raúl; Loubat, Jordina; Alameda Quitllet, Francisco; Rodríguez, Rufo; Curto, Josué; Albanell, Joan; Muñoz, Alberto; Bonilla, Félix; Casal, José Ignacio; Rojo, Federico; García de Herreros, Antonio (Elsevier, 2014)
    Snail1 transcriptional repressor is a major inducer of epithelial-to mesenchymal transition but is very limitedly expressed in adult animals. We have previously demonstrated that Snail1 is required for the maintenance of ...

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