Browsing by Author "Consiglio, Antonella"

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  • Rodríguez Pizà, Ignasi; Raya Chamorro, Ángel; Navarro, Susana; Izpisúa Belmonte, J. C.; Bueren, Juan; Consiglio, Antonella; Sánchez Danés, Adriana, 1984-; Guenechea, Guillermo; Richaud Patin, Yvonne (Nature Publishing Group, 2010)
    The generation of patient-specific induced pluripotent stem cells (iPSCPSCPSCs) offers unprecedented opportunities for modeling and treating human disease. In combination with gene therapy, the iPSCPSCPSC technology can ...
  • Rodríguez Pizà, Ignasi; Raya Chamorro, Ángel; Aran, Begoña; Veiga, Anna; Izpisúa Belmonte, J. C.; Barri, Pere N.; Muñoz, Yolanda; Consiglio, Antonella (Springer, 2010)
    We report here the legislative issues related to/nembryo research and human embryonic stem cell (hESC)/nresearch in Spain and the derivation of nine hESC lines at/nthe Center of Regenerative Medicine in Barcelona. You ...
  • Rodríguez Pizà, Ignasi; Verma, Inder M.; Veiga, Anna; Aasen, Trond; Izpisúa Belmonte, J. C.; Bueren, Juan; Garreta Bahima, Elena; Tiscornia, Gustavo; Sleep Ronquillo, Eduard; Raya Chamorro, Ángel; Río, Paula; Consiglio, Antonella; Barrero Núñez, María José; Navarro, Susana; Vassena, Rita; Guenechea, Guillermo (Nature Publishing Group, 2009)
    The generation of induced pluripotent stem (iPS) cells has enabled the derivation of patient-specific pluripotent cells and/nprovided valuable experimental platforms to model human disease. Patient-specific iPS cells are ...
  • Raya Chamorro, Ángel; Rodríguez Pizà, Ignasi; Aran, Begoña; Consiglio, Antonella; Barri, Pere N.; Veiga, Anna; Izpisúa Belmonte, J. C. (Cold Spring Harbor Laboratory Press-CSHL Press, 2008)
    Human embryonic stem (hES) cells represent a potential source for cell replacement therapy of many degenerative diseases. Most frequently, hES cell lines are derived from surplus embryos from assisted reproduction cycles, ...
  • Sánchez Danés, Adriana, 1984- (Universitat Pompeu Fabra, 2012-05-21)
    Parkinson’s disease (PD) is an incurable, chronically progressive neurodegenerative disease leading to premature invalidity and death. The locomotor disability of PD patients is mainly rooted in the gradual and insidious ...
  • Carola, Giulia; Malagarriga, Daniel; Calatayud, Carles; Pons Espinal, Meritxell, 1986-; Blasco Agell, Lucas; Richaud Patin, Yvonne; Fernández Carasa, Irene; Baruffi, Valentina; Beltramone, Santiago; Molina, Emilio; Dell'Era, Patrizia; Toledo Aral, Juan J.; Tolosa, Eduard; Muotri, Alysson R.; García Ojalvo, Jordi; Soriano Fradera, Jordi; Raya Chamorro, Ángel; Consiglio, Antonella (Nature Research, 2021)
    A deeper understanding of early disease mechanisms occurring in Parkinson's disease (PD) is needed to reveal restorative targets. Here we report that human induced pluripotent stem cell (iPSC)-derived dopaminergic neurons ...
  • di Domenico, Angelique; Carola, Giulia; Calatayud, Carles; Pons Espinal, Meritxell, 1986-; Muñoz, Juan Pablo; Richaud Patin, Yvonne; Fernández Carasa, Irene; Gut, Marta; Faella, Armida; Parameswaran, Janani, 1990-; Soriano, Jordi; Ferrer, Isidre; Tolosa, Eduard; Zorzano, Antonio; Cuervo, Ana Maria; Raya Chamorro, Ángel; Consiglio, Antonella (Elsevier, 2019)
    Parkinson's disease (PD) is associated with the degeneration of ventral midbrain dopaminergic neurons (vmDAns) and the accumulation of toxic α-synuclein. A non-cell-autonomous contribution, in particular of astrocytes, ...
  • Fernández-Santiago, Ruben; Merkel, Angelika; Castellano, Giancarlo; Heath, Simon; Raya Chamorro, Ángel; Tolosa, Eduard; Martí, Maria José; Consiglio, Antonella; Ezquerra, Mario (BioMed Central, 2019)
    Background: Parkinson’s disease (PD) is characterized by the loss of midbrain dopaminergic neurons (DAn). Previously, we described the presence of DNA hyper- and hypo-methylation alterations in induced pluripotent stem ...

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