Browsing by Author "Comerma Blesa, Laura, 1983-"

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  • Differences in breast cancer risk after benign breast disease by type of screening diagnosis
    Louro, Javier; Román, Marta; Posso, Margarita; Comerma Blesa, Laura, 1983-; Vidal, Carmen; Saladié, Francina; Alcántara da Silva, Rodrigo; Sánchez, Mar; Quintana, María Jesús; Del Riego, Javier; Ferrer, Joana; Peñalva, Lupe; Bargalló Castelló, Xavier; Prieto, Miguel; Sala Serra, Maria; Castells, Xavier (Elsevier, 2020)
    Introduction: We aimed to assess differences in breast cancer risk across benign breast disease diagnosed at prevalent or incident screens. Materials and methods: We conducted a retrospective cohort study with data from ...
  • Glutamine-directed migration of cancer-activated fibroblasts facilitates epithelial tumor invasion
    Mestre-Farrera, Aida, 1992-; Bruch-Oms, Marina; Peña Arranz, Raúl; Rodríguez-Morató, Jose, 1987-; Alba Castellón, Lorena, 1984-; Comerma Blesa, Laura, 1983-; Quintela-Fandino, Miguel; Duñach, Mireia; Baulida i Estadella, Josep, 1965-; Pozo Mendoza, Óscar J., 1975-; García de Herreros, Antonio (American Association for Cancer Research (AACR), 2021)
    Tumors are complex tissues composed of transformed epithelial cells as well as cancer-activated fibroblasts (CAF) that facilitate epithelial tumor cell invasion. We show here that CAFs and other mesenchymal cells rely much ...
  • Identification and characterization of a novel population of memory B cells in the human intestine
    Comerma Blesa, Laura, 1983- (Universitat Pompeu Fabra, 2016-07-12)
    We found that IgM+IgD- memory (ME-M) B cells formed a large reservoir of intestinal antigen-selected IgM+ lymphocytes distinct from antigen-naïve IgM+ lymphocytes. Human ME-M B cells colonized the intestine early in life, ...
  • LCOR mediates interferon-independent tumor immunogenicity and responsiveness to immune-checkpoint blockade in triple-negative breast cancer
    Pérez-Núñez, Iván; Rozalén, Catalina; Palomeque, José Ángel; Sangrador, Irene; Dalmau, Mariona; Comerma Blesa, Laura, 1983-; Hernández Prat, Anna, 1984-; Casadevall Aguilar, David; Menendez Romero, Silvia; Liu, Daniel Dan; Berenguer De Felipe, Jordi; Peña Arranz, Raúl, 1976; Montañés, José Carlos; Albà Soler, Mar; Bonnin, Sarah; Ponomarenko, Julia; Servitja Tormo, Sonia; Arribas, Joaquín; Albanell Mestres, Joan; Celià-Terrassa, Toni (Nature Research, 2022)
    Ligand-dependent corepressor (LCOR) mediates normal and malignant breast stem cell differentiation. Cancer stem cells (CSCs) generate phenotypic heterogeneity and drive therapy resistance, yet their role in immunotherapy ...
  • Palbociclib rechallenge for hormone receptor-positive/HER-negative advanced breast cancer: findings from the phase II BioPER trial
    Albanell Mestres, Joan; Comerma Blesa, Laura, 1983-; Gibert, Joan; Bellosillo Paricio, Beatriz; Menéndez, Silvia; Llombart-Cussac, Antonio (American Association for Cancer Research (AACR), 2023)
    Purpose: to assess the efficacy and exploratory biomarkers of continuing palbociclib plus endocrine therapy (ET) beyond progression on prior palbociclib-based regimen in patients with hormone receptor-positive/HER2-negative ...
  • PD-L1 testing based on the SP142 antibody in metastatic triple-negative breast cancer: summary of an expert round-table discussion
    Peg, Vicente; López-García, María Ángeles; Comerma Blesa, Laura, 1983-; Peiró, Gloria; García-Caballero, Tomás; Concha López, Ángel; Suárez-Gauthier, Ana; Ruiz, Irune; Rojo, Federico (Future Medicine, 2021)
    Triple-negative breast cancer (TNBC) is more aggressive than other breast cancer subtypes. TNBC is characterized by increased expression of Programmed Death-ligand 1 (PD-L1), a signal used by many tumors to escape the ...
  • Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer
    Kos, Zuzana; Comerma Blesa, Laura, 1983-; Salgado, Roberto; International Immuno-Oncology Biomarker Working Group (Nature Research, 2020)
    Stromal tumor-infiltrating lymphocytes (sTILs) are important prognostic and predictive biomarkers in triple-negative (TNBC) and HER2-positive breast cancer. Incorporating sTILs into clinical practice necessitates reproducible ...
  • Snail1 expression in endothelial cells controls growth, angiogenesis and differentiation of breast tumors
    Cabrerizo Granados, David, 1993-; Peña Arranz, Raúl; Palacios, Laura; Carrillo-Bosch, Laura; Lloreta-Trull, Josep; Comerma Blesa, Laura, 1983-; Iglesias Coma, Mar; García de Herreros, Antonio (Ivyspring International Publisher, 2021)
    Snail1 is a transcriptional factor required for epithelial to mesenchymal transition and activation of cancer-associated fibroblasts (CAF). Apart from that, tumor endothelial cells also express Snail1. Here, we have unraveled ...