Browsing by Author "Coll, Olga"

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  • Ataxin-2, Twenty-four, and Dicer-2 are components of a noncanonical cytoplasmic polyadenylation complex
    Nadimpalli, Hima Priyanka, 1988-; Guitart, Tanit; Coll, Olga; Gebauer, Fátima (Life Science Alliance, 2022)
    Cytoplasmic polyadenylation is a mechanism to promote mRNA translation in a wide variety of biological contexts. A canonical complex centered around the conserved RNA-binding protein family CPEB has been shown to be ...
  • Cold-inducible RNA binding protein promotes breast cancer cell malignancy by regulating Cystatin C levels
    Indacochea Cusirramos, Alberto; Guerrero Jijon, Santiago Xavier; Ureña, Macarena; Araujo, Ferrán; Coll, Olga; Lleonart, Matilde E.; Gebauer, Fátima (Cold Spring Harbor Laboratory Press (CSHL Press), 2021)
    Cold-inducible RNA binding protein (CIRBP) is a stress-responsive protein that promotes cancer development and inflammation. Critical to most CIRBP functions is its capacity to bind and posttranscriptionally modulate mRNA. ...
  • Coordinated post-transcriptional control of oncogene-induced senescence by UNR/CSDE1
    Avolio, Rosario; Inglés Ferrándiz, Marta, 1989-; Ciocia, Annagiulia; Coll, Olga; Bonnin, Sarah; Guitart, Tanit; Ribó Rubio, Anna; Gebauer, Fátima (Elsevier, 2022)
    Oncogene-induced senescence (OIS) is a form of stable cell-cycle arrest arising in response to oncogenic stimulation. OIS must be bypassed for transformation, but the mechanisms of OIS establishment and bypass remain poorly ...
  • Dicer-2 promotes mRNA activation through cytoplasmic polyadenylation
    Coll, Olga; Guitart, Tanit; Villalba, Ana; Papin, Catherine; Simonelig, Martine; Gebauer, Fátima (Cold Spring Harbor Laboratory Press (CSHL Press), 2018)
    Cytoplasmic polyadenylation is a widespread mechanism to regulate mRNA translation. In vertebrates, this process requires two sequence elements in target 3' UTRs: the U-rich cytoplasmic polyadenylation element and the ...
  • Hrp48 and eIF3d contribute to msl-2 mRNA translational repression
    Szóstak, Emilia, 1984-; García Beyaert, Marina, 1983-; Guitart, Tanit; Graindorge, Antoine; Coll, Olga; Gebauer, Fátima (Oxford University Press, 2018)
    Translational repression of msl-2 mRNA in females of Drosophila melanogaster is an essential step in the regulation of X-chromosome dosage compensation. Repression is orchestrated by Sex-lethal (SXL), which binds to both ...
  • Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis
    Mestre-Farràs, Neus; Guerrero Jijon, Santiago Xavier; Bley, Nadine; Rivero, Ezequiel; Coll, Olga; Borràs, Eva; Sabidó Aguadé, Eduard, 1981-; Indacochea Cusirramos, Alberto; Casillas-Serra, Carlos; Järvelin, Aino I.; Oliva Miguel, Baldomero; Castello, Alfredo; Hüttelmaier, Stefan; Gebauer, Fátima (Oxford University Press, 2022)
    RNA-binding proteins (RBPs) have been relatively overlooked in cancer research despite their contribution to virtually every cancer hallmark. Here, we use RNA interactome capture (RIC) to characterize the melanoma RBPome ...