Browsing by Author "Coen, Muireann"

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  • Assessment of metabolic phenotypic variability in children’s urine using 1H NMR spectroscopy
    Maitre, Léa; Lau, Chung-Ho E.; Vizcaino, Esther; Robinson, Oliver; Casas Sanahuja, Maribel; Siskos, Alexandros P.; Want, Elizabeth J.; Athersuch, Toby J.; Slama, Rémy; Vrijheid, Martine; Keun, Hector C.; Coen, Muireann (Nature Research, 2017)
    The application of metabolic phenotyping in clinical and epidemiological studies is limited by a poor understanding of inter-individual, intra-individual and temporal variability in metabolic phenotypes. Using 1H NMR ...
  • Determinants of the urinary and serum metabolome in children from six European populations
    Lau, Chung-Ho E.; Maitre, Léa; Urquiza, José M.; Casas Sanahuja, Maribel; Vrijheid, Martine; Coen, Muireann (BioMed Central, 2018)
    Background: Environment and diet in early life can affect development and health throughout the life course. Metabolic phenotyping of urine and serum represents a complementary systems-wide approach to elucidate ...
  • Maternal urinary metabolic signatures of fetal growth and associated clinical and environmental factors in the INMA study.
    Maitre, Léa; Villanueva Belmonte, Cristina; Lewis, Matthew R.; Ibarluzea, Jesús; Santa Marina, Loreto; Vrijheid, Martine; Sunyer Deu, Jordi; Coen, Muireann; Toledano, Mireille B. (BioMed Central, 2016)
    BACKGROUND: Maternal metabolism during pregnancy is a major determinant of the intra-uterine environment and fetal outcomes. Herein, we characterize the maternal urinary metabolome throughout pregnancy to identify maternal ...
  • Urinary metabolite quantitative trait loci in children and their interaction with dietary factors
    Calvo Serra, Beatriz; Maitre, Léa; Lau, Chung-Ho E.; Siskos, Alexandros P.; Gützkow, Kristine B.; Andrušaitytė, Sandra; Casas Sanahuja, Maribel; Cadiou, Solène; Chatzi, Leda; González, Juan Ramón; Gražulevičienė, Regina; McEachan, Rosemary R.C.; Slama, Rémy; Vafeiadi, Marina, 1983-; Wright, John; Coen, Muireann; Vrijheid, Martine; Keun, Hector C.; Escaramís, Geòrgia; Bustamante Pineda, Mariona (Oxford University Press, 2021)
    Human metabolism is influenced by genetic and environmental factors. Previous studies have identified over 23 loci associated with more than 26 urine metabolites levels in adults, which are known as urinary metabolite ...
  • Urine metabolic signatures of multiple environmental pollutants in pregnant women: an exposome approach
    Maitre, Léa; Robinson, Oliver; Martínez, David; Toledano, Mireille B.; Ibarluzea, Jesús; Marina, Loreto Santa; Sunyer Deu, Jordi; Villanueva, Cristina M.; Keun, Hector C.; Vrijheid, Martine; Coen, Muireann (American Chemical Society (ACS), 2018)
    Exposure to environmental pollutants, particularly during pregnancy, can have adverse consequences on child development but little is known about the effects of pollutant mixtures on endogenous metabolism in pregnant women. ...

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