Browsing by Author "Cianferoni, Damiano"

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  • Cianferoni, Damiano (Universitat Pompeu Fabra, 2023-10-17)
    Aquesta tesi presenta diversos avenços que inclouen: (i) noves funcionalitats afegides a la “suite” d'eines de disseny de proteïnes FoldX per permetre als usuaris treballar amb qualsevol tipus de molècula; (ii) estudis ...
  • Delgado Blanco, Javier; Radusky, Leandro; Cianferoni, Damiano; Serrano Pubull, Luis, 1982- (Oxford University Press, 2019)
    SUMMARY: A new version of FoldX, whose main new features allows running classic FoldX commands on structures containing RNA molecules and includes a module that allows parametrization of ligands or small molecules (ParamX) ...
  • Delgado Blanco, Javier; Hernandez-Alias, Xavier; Cianferoni, Damiano; Serrano Pubull, Luis, 1982- (Public Library of Science (PLoS), 2020)
    The coronavirus disease COVID-19 constitutes the most severe pandemic of the last decades having caused more than 1 million deaths worldwide. The SARS-CoV-2 virus recognizes the angiotensin converting enzyme 2 (ACE2) on ...
  • Pascual-Reguant, Laura; Datta, Debayan; Cianferoni, Damiano; Kourtis, Savvas; Gañez-Zapater, Antoni; Cannatá, Chiara; Espinar, Lorena; García López, Laura; Musa-Afaneh, Sara; Guirola, Maria; Gkanogiannis, Anestis; Miró Canturri, Andrea; Arribas, Joaquín; Serrano Pubull, Luis, 1982-; Sdelci, Sara (EMBO Press, 2023)
    Triple-negative breast cancer (TNBC) often develops resistance to single-agent treatment, which can be circumvented using targeted combinatorial approaches. Here, we demonstrate that the simultaneous inhibition of LOXL2 ...
  • Delgado Blanco, Javier; Radusky, Leandro; Cianferoni, Damiano; Serrano Pubull, Luis, 1982- (National Academy of Sciences, 2019)
    RNA-protein interactions are crucial for such key biological processes as regulation of transcription, splicing, translation, and gene silencing, among many others. Knowing where an RNA molecule interacts with a target ...
  • Cianferoni, Damiano; Radusky, Leandro; Head, Sarah A.; Serrano Pubull, Luis, 1982-; Delgado Blanco, Javier (Oxford University Press, 2020)
    Summary: Accurate 3D modelling of protein-protein interactions (PPI) is essential to compensate for the absence of experimentally determined complex structures. Here, we present a new set of commands within the ModelX ...
  • Najle, Sebastián R.; Grau Bové, Xavier; Elek, Anamaria; Navarrete Hernández, Cristina; Cianferoni, Damiano; Chiva, Cristina; Cañas Armenteros, Didac; Mallabiabarrena, Arrate; Kamm, Kai; Sabidó Aguadé, Eduard, 1981-; Gruber-Vodicka, Harald; Schierwater, Bernd; Serrano Pubull, Luis, 1982-; Sebé-Pedrós, Arnau (Elsevier, 2023)
    The assembly of the neuronal and other major cell type programs occurred early in animal evolution. We can reconstruct this process by studying non-bilaterians like placozoans. These small disc-shaped animals not only have ...

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