Browsing by Author "Chiva, Cristina"

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  • Liñeiro, Eva; Chiva, Cristina; Cantoral, Jesús M.; Sabidó Aguadé, Eduard, 1981-; Fernández-Acero, Francisco Javier (Elsevier, 2016)
    Phosphorylation is one of the main post-translational modification (PTM) involved in signaling network in the ascomycete Botrytis cinerea, one of the most relevant phytopathogenic fungus. The data presented in this article ...
  • Espadas, Guadalupe; Borràs, Eva; Chiva, Cristina; Sabidó Aguadé, Eduard, 1981- (Wiley, 2017)
    One of the major additions in MS technology has been the irruption of the Orbitrap mass analyzer, which has boosted the proteomics analyses of biological complex samples since its introduction. Here, we took advantage of ...
  • Chiva, Cristina; Pastor, Olga; Trilla Fuertes, Lucía; Gámez Pozo, Angelo; Fresno Vara, Juan Ángel; Sabidó Aguadé, Eduard, 1981- (American Chemical Society (ACS), 2019)
    Targeted proteomics has become the method of choice for biomarker validation in human biopsies due to its high sensitivity, reproducibility, accuracy, and precision. However, for targeted proteomics to be transferred to ...
  • Campos, Alex; Díaz, Ramón; Martínez Bartolomé, Salvador; Sierra, Jose; Gallardo, Oscar; Sabidó Aguadé, Eduard, 1981-; López Lucendo, María; Casal, José Ignacio; Pasquarello, Carla; Scherl, Alexander; Chiva, Cristina; Borrás, Eva; Odena, Antonia; Elortza, Félix; Azkargorta, Mikel; Ibarrola, Nieves; Canals, Francesc; Albar, Juan P.; Oliveira, Eliandre (Elsevier, 2015)
    Proteomic technologies based on mass spectrometry (MS) have greatly evolved in the past years, and nowadays it is possible to routinely identify thousands of peptides from complex biological samples in a single LC-MS/MS ...
  • Ruiz Orera, Jorge, 1988-; Hernández Rodríguez, Jéssica, 1983-; Chiva, Cristina; Sabidó Aguadé, Eduard, 1981-; Kondova, Ivanela; Bontrop, Ronald E.; Marquès i Bonet, Tomàs, 1975-; Albà Soler, Mar (Public Library of Science, 2015)
    The birth of new genes is an important motor of evolutionary innovation. Whereas many new genes arise by gene duplication, others originate at genomic regions that did not contain any genes or gene copies. Some of these ...
  • Chiva, Cristina; Sabidó Aguadé, Eduard, 1981- (American Chemical Society (ACS), 2017)
    Targeted proteomics methods in their different flavors rely on the use of a few peptides as proxies for protein quantitation, which need to be specified either prior to or after data acquisition. However, in contrast with ...
  • Gámez Pozo, Angelo; Trilla Fuertes, Lucía; Prado Vázquez, Guillermo; Chiva, Cristina; López Vacas, Rocío; Nanni, Paolo; Berges Soria, Julia; Grossmann, Jonas; Díaz Almirón, Mariana; Ciruelos, E.; Sabidó Aguadé, Eduard, 1981-; Espinosa Arranz, Enrique; Fresno Vara, Juan Ángel (Public Library of Science (PLoS), 2017)
    BACKGROUND: Triple-negative breast cancer (TNBC) accounts for 15-20% of all breast cancers and usually requires the administration of adjuvant chemotherapy after surgery but even with this treatment many patients still ...
  • Borrás, Eva; Cantó, Ester; Choi, Meena; Villar, Luisa Maria; Álvarez Cermeño, Jose Carlos; Chiva, Cristina; Montalbán Gairín, Xavier; Vitek, Olga; Comabella López, Manuel; Sabidó Aguadé, Eduard, 1981- (American Society for Biochemistry and Molecular Biology (ASBMB), 2016)
    Multiple sclerosis is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system. In most patients, the disease initiates with an episode of neurological disturbance referred to as clinically ...
  • Rojas Laimito, Katerin; Trilla Fuertes, Lucía; Gámez Pozo, Angelo; Chiva, Cristina; Sepúlveda, Juan M.; Manso, Luis; Prado Vázquez, Guillermo; Zapater-Moros, Andrea; López Vacas, Rocío; Ferrer-Gómez, María; Mendiola, César; Espinosa Arranz, Enrique; Sabidó Aguadé, Eduard, 1981-; Ciruelos, Eva; Fresno Vara, Juan Ángel (Cancer Intelligence, 2019)
    Background: Breast cancer (BC) is the most frequent tumour in women. Triple negative tumours (TNBC)–which are associated with minor survival rates—lack markers predictive of response to anticancer drugs. Triple negative ...
  • Sebé-Pedrós, Arnau; Ballaré, Cecilia Julia; Parra-Acero, Helena; Chiva, Cristina; Tena, Juan J.; Sabidó Aguadé, Eduard, 1981-; Gómez Skarmeta, José Luis; Di Croce, Luciano; Ruíz Trillo, Iñaki (Elsevier, 2016)
    The unicellular ancestor of animals had a complex repertoire of genes linked to multicellular processes. This suggests that changes in the regulatory genome, rather than in gene innovation, were key to the origin of animals. ...
  • Cantó, Ester; Tintoré, Mar; Villar, Luisa Maria; Borrás, Eva; Álvarez Cermeño, Jose Carlos; Chiva, Cristina; Sabidó Aguadé, Eduard, 1981-; Rovira, Alex; Montalbán Gairín, Xavier; Comabella López, Manuel (BioMed Central, 2014)
    Background: In a previous proteomics study using pooled cerebrospinal fluid (CSF) samples, we proposed apolipoprotein AI, apolipoprotein AIV, vitronectin, plasminogen, semaphorin 7A, and ala-?-his-dipeptidase as candidate ...