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Browsing by Author "Cecchini Rosell, Lluís"

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A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

López De Maturana, Evangelina; Rodríguez, Juan Antonio; Lao Grueso, Oscar, 1976-; Iglesias Coma, Mar; Cecchini Rosell, Lluís; Ilzarbe Sánchez, Lucas; Real, Francisco X.; Malats i Riera, Núria (BioMed Central, 2021)

Background: Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% ...
ERG overexpression plus SLC45A3 (prostein) and PTEN expression loss: Strong association of the triple hit phenotype with an aggressive pathway of prostate cancer progression

Hernández Llodrà, Silvia; Juanpere, Nuria; Muga, Silvia de; Lorenzo Perez, Marta; Gil Ortega, Joan; Font Tello, Alba 1990-; Agell, Laia; Albero-González, Raquel; Segalés, Laura; Merino, José; Serrano, Laia; Fumadó Ciutat, Lluis; Cecchini Rosell, Lluís; Lloreta Trull, Josep, 1958- (Impact Journals, 2017)

TMPRSS2 and SLC45A3 rearrangements may coexist in the same tumor. ERG rearrangements and PTEN loss are concomitant events in prostate cancer (PrCa), and can cooperate in progression. We have reported that mRNA expression ...
FOXO1 down-regulation is associated with worse outcome in bladder cancer and adds significant prognostic information to p53 overexpression

Lloreta Trull, Josep, 1958-; Font-Tello, Alba; Juanpere, Nuria; Frances, Albert; Lorenzo Perez, Marta; Nonell Mazelón, Lara; Muga, Silvia de; Vázquez‐de las Heras, Ivonne; Cecchini Rosell, Lluís; Hernández, Silvia (Elsevier, 2017)

Nuclear FOXOs mediate cell cycle arrest and promote apoptosis. FOXOs and p53 could have similar effects as tumor suppressor genes. In spite of extensive literature, little is known about the role of FOXO1 and its relationship ...
Health-related quality of life in men with prostate cancer undergoing active surveillance versus radical prostatectomy, external-beam radiotherapy, prostate brachytherapy and reference population: a cross-sectional study

Sureda Gomila, Antoni; Fumadó Ciutat, Lluis; Ferrer Forés, Maria Montserrat; Garín, O.; Bonet, X.; Mir, M.C.; Abascal, J.M.; Vigués, F.; Cecchini Rosell, Lluís; Suárez Novo, José Francisco (BioMed Central, 2019)

BACKGROUND: The purpose of this study is to describe Health-Related Quality of Life (HRQoL) of localized prostate cancer patients in an Active Surveillance (AS) program, and to compare them with those undergoing radical ...
MDRD o CKD-EPI en la estimación del filtrado glomerulardel donante renal vivo

Burballa Tàrrega, Carla, 1988-; Crespo Barrio, Marta; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Mir Fontana, M. Luisa; Arias Cabrales, Carlos Enrique; Frances, Albert; Fumadó Ciutat, Lluis; Cecchini Rosell, Lluís; Pascual Santos, Julio (Elsevier, 2018)

INTRODUCTION: The evaluation of the measured Glomerular Filtration Rate (mGFR) or estimated Glomerular Filtration Rate (eGFR) is key in the proper assessment of the renal function of potential kidney donors. We aim to study ...
Prostate cancer genetic propensity risk score may modify the association between this tumour and type 2 diabetes mellitus (MCC-Spain study)

Barrios-Rodríguez, Rocío; García-Esquinas, Esther; Pérez-Gómez, Beatriz; Castaño Vinyals, Gemma; Llorca, Javier; Fernández de Larrea-Baz, Nerea; Olmedo-Requena, Rocío; Vanaclocha-Espi, Mercedes; Alguacil Ojeda, Juan; Fernández-Tardón, Guillermo; Fernández-Navarro, Pablo; Cecchini Rosell, Lluís; Lope, Virginia; Gómez-Acebo, Inés; Aragonés, Núria; Kogevinas, Manolis; Pollan, Marina; Jiménez-Moleón, José Juan (Nature Research, 2022)

Background: Some studies have reported an inverse association between type 2 diabetes mellitus (T2DM) and prostate cancer (PCa), but results on this issue are still inconsistent. In this study, we evaluate whether this ...
Sentinel lymph node biopsy in prostate cancer patients: results from an injection technique targeting the index lesion in the prostate gland

Fumadó Ciutat, Lluis; Abascal, J.M.; Mestre-Fusco, Antoni; Vidal-Sicart, Sergi; Aguilar, Guadalupe; Juanpere, Nuria; Cecchini Rosell, Lluís (Frontiers, 2022)

Objectives: to determine the accuracy of nodal staging in patients with prostate cancer (PCa) when 99 m Tc-nanocolloid radiotracer is injected into an index lesion (IL). Methods: this prospective study was conducted at our ...
SPOP and CHD1 alterations in prostate cancer: Relationship with PTEN loss, tumor grade, perineural infiltration, and PSA recurrence

Hernández Llodrà, Silvia; Segalés Tañà, Laura, 1994-; Juanpere, Nuria; Lorenzo, Marta; Salido Galeote, Marta; Nonell Mazelón, Lara; López, David; Rodríguez-Vida, Alejo; Bellmunt Molins, Joaquim, 1959-; Fumadó Ciutat, Lluis; Cecchini Rosell, Lluís; Lloreta Trull, Josep, 1958- (Wiley, 2021)

Background: In the non-ETS fusion of prostate cancer (PCa) pathway, SPOP mutations emerge as a distinct oncogenic driver subclass. Both SPOP downregulation and mutation can lead to SPOP target stabilization promoting ...
Structural differences in the diaphragm of patients following controlled vs assisted and spontaneous mechanical ventilation

Marin Corral, Judith; Dot Jordana, Irene, 1982-; Boguñá, Marián; Cecchini Rosell, Lluís; Zapatero, Ana; Gracia Arnillas, María Pilar; Pascual Guàrdia, Sergi, 1979-; Vilà Vilardell, Clara; Castellví, A.; Pérez-Terán, Purificación; Gea Guiral, Joaquim; Masclans Enviz, Joan Ramon (Springer, 2019)

Purpose: Ventilator-induced diaphragm dysfunction or damage (VIDD) is highly prevalent in patients under mechanical ventilation (MV), but its analysis is limited by the difficulty of obtaining histological samples. In this ...

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Browsing by Author "Cecchini Rosell, Lluís"

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