Browsing by Author "Castillo Andreo, David"

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  • Mendieta Esteban, Julen, 1992-; Di Stefano, Marco; Castillo Andreo, David; Farabella, Irene; Marti-Renom, Marc A. (Oxford University Press, 2021)
    Chromosome conformation capture (3C) technologies measure the interaction frequency between pairs of chromatin regions within the nucleus in a cell or a population of cells. Some of these 3C technologies retrieve interactions ...
  • Sati, Satish; Serra, François; Castillo Andreo, David; Marti-Renom, Marc A.; Cavalli, Giacomo (Cell Press, 2020)
    To understand the role of the extensive senescence-associated 3D genome reorganization, we generated genome-wide chromatin interaction maps, epigenome, replication-timing, whole-genome bisulfite sequencing, and gene ...
  • Vega, Montserrat; Castillo Andreo, David; de Cubas, Laura; Wang, Yirong; Huang, Ying; Hidalgo Hernando, Elena (BioMed Central, 2022)
    Background: In many organisms, aging is characterized by a loss of mitochondrial homeostasis. Multiple factors such as respiratory metabolism, mitochondrial fusion/fission, or mitophagy have been linked to cell longevity, ...
  • Serra, François; Baù, Davide; Goodstadt, Michael; Castillo Andreo, David; Filion, Guillaume; Martí Renom, Marc A. (Public Library of Science (PLoS), 2017)
    The sequence of a genome is insufficient to understand all genomic processes carried out in the cell nucleus. To achieve this, the knowledge of its three-dimensional architecture is necessary. Advances in genomic technologies ...
  • Spill, Yannick G.; Castillo Andreo, David; Vidal, Enrique; Marti-Renom, Marc A. (Nature Research, 2019)
    Chromosome conformation capture techniques, such as Hi-C, are fundamental in characterizing genome organization. These methods have revealed several genomic features, such as chromatin loops, whose disruption can have ...
  • Vega, Montserrat; Barrios, Rubén; Fraile Beneitez, Rodrigo, 1992-; Castro Cogle, Kevin de; Castillo Andreo, David; Anglada Busquets, Roger; Casals López, Ferran; Ayté del Olmo, José; Lowy Gallego, Ernesto; Hidalgo Hernando, Elena (Oxford University Press, 2023)
    Chromatin remodeling is essential to allow full development of alternative gene expression programs in response to environmental changes. In fission yeast, oxidative stress triggers massive transcriptional changes including ...
  • Di Stefano, Marco; Stadhouders, Ralph; Farabella, Irene; Castillo Andreo, David; Serra, François; Graf, T. (Thomas); Marti-Renom, Marc A. (Nature Research, 2020)
    Chromosome structure is a crucial regulatory factor for a wide range of nuclear processes. Chromosome conformation capture (3C)-based experiments combined with computational modelling are pivotal for unveiling 3D chromosome ...

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