Browsing by Author "Castellano, Giancarlo"

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  • Wright, Roni H.G.; Castellano, Giancarlo; Bonet Martínez, Jaume, 1982-; Le Dily, François; Font Mateu, Jofre, 1977-; Ballaré, Cecilia Julia; Nacht, A. Silvina; Soronellas, Daniel; Oliva Miguel, Baldomero; Beato, Miguel (Cold Spring Harbor Laboratory Press (CSHL Press), 2012)
    Eukaryotic gene regulation implies that transcription factors gain access to genomic information via poorly understood processes involving activation and targeting of kinases, histone-modifying enzymes, and chromatin ...
  • Jiménez, Natalia; Reig, Òscar; Montalbo, Ruth; Milà-Guasch, Maria; Nadal-Dieste, Lluis; Castellano, Giancarlo; Lozano, Juan José; Victoria, Iván; Font, Albert; Rodriguez-Vida, Alejo; Carles, Joan; Suárez, Cristina; Doménech, Montserrat; Sala-González, Núria; Fernández, Pedro Luís; Rodríguez-Carunchio, Leonardo; Díaz, Sherley; Prat, Aleix; Marín-Aguilera, Mercedes; Mellado, Begoña (Frontiers, 2020)
    The prostatic tumor cells plasticity is involved in resistance to hormone-therapy, allowing these cells to survive despite androgen receptor inhibition. However, its role in taxanes resistance has not been fully established. ...
  • Le Dily, François; Baù, Davide; Pohl, Andy, 1979-; Vicent, Guillermo Pablo; Serra, François; Soronellas, Daniel; Castellano, Giancarlo; Wright, Roni H.G.; Ballare, Cecilia Julia; Filion, Guillaume; Marti-Renom, Marc A.; Beato, Miguel (Cold Spring Harbor Laboratory Press (CSHL Press), 2014)
    The human genome is segmented into topologically associating domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we describe the distribution of ...
  • Ballaré, Cecilia Julia; Castellano, Giancarlo; Gaveglia, Laura; Althammer, Sonja Daniela; González-Vallinas Rostes, Juan, 1983-; Eyras Jiménez, Eduardo; Le Dily, François; Zaurín Quer, Roser; Soronellas, Daniel; Vicent, Guillermo Pablo; Beato, Miguel (Elsevier, 2013)
    In fission yeast cells, Cds1 is the effector kinase of the DNA replication checkpoint. We previously showed that when the DNA replication checkpoint is activated, the repressor Yox1 is phosphorylated and inactivated by ...
  • Bertucci, Paola Y.; Nacht, A. Silvina; Alló, Mariano; Rocha-Viegas, Luciana; Ballaré, Cecilia Julia; Soronellas, Daniel; Castellano, Giancarlo; Zaurín Quer, Roser; Kornblihtt, Alberto R.; Beato, Miguel; Vicent, Guillermo Pablo; Pecci, Adali (Oxford University Press, 2013)
    Steroid receptors were classically described for regulating transcription by binding to target gene promoters. However, genome-wide studies reveal that steroid receptors-binding sites are mainly located at intragenic ...
  • Fernández-Santiago, Ruben; Merkel, Angelika; Castellano, Giancarlo; Heath, Simon; Raya Chamorro, Ángel; Tolosa, Eduard; Martí, Maria José; Consiglio, Antonella; Ezquerra, Mario (BioMed Central, 2019)
    Background: Parkinson’s disease (PD) is characterized by the loss of midbrain dopaminergic neurons (DAn). Previously, we described the presence of DNA hyper- and hypo-methylation alterations in induced pluripotent stem ...

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