Browsing by Author "Castaño, Justo P."

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  • A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1
    Closa, Adrià; Reixachs-Solé, Marina; Fuentes-Fayos, Antonio C.; Hayer, Katharina E.; Melero, Juan L.; Adriaanse, Fabienne R.S.; Bos, Romy S.; Torres-Diz, Manuel; Hunger, Stephen P.; Roberts, Kathryn G.; Mullighan, Charles G.; Stam, Ronald W.; Thomas-Tikhonenko, Andrei; Castaño, Justo P.; Luque, Raul M.; Eyras Jiménez, Eduardo (Oxford University Press, 2022)
    A significant proportion of infant B-cell acute lymphoblastic leukemia (B-ALL) patients remains with a dismal prognosis due to yet undetermined mechanisms. We performed a comprehensive multicohort analysis of gene expression, ...
  • A longitudinal study of free leptin index in pre-eclamptic pregnancies
    Garcés, María Fernanda; Buell-Acosta, Julieth Daniela; Rodríguez-Navarro, Haiver Antonio; Páez-Leal, María Carolina; Maldonado-Acosta, Luis Miguel; Peralta-Franco, Jhon Jairo; Burgos-Cardenas, Álvaro Javier; Ángel-Müller, Edith; Parada-Baños, Arturo José; Parra-Pineda, Mario Orlando; Eslava-Schmalbach, Javier; Escobar-Sarmiento, Camilo Andrés; Lacunza, Ezequiel; Caminos-Cepeda, Sofia Alexandra; Castaño, Justo P.; Nogueiras, Ruben; Dieguez, Carlos; Ruiz-Parra, Ariel Iván; Caminos, Jorge Eduardo (Wiley, 2023)
    The ratio between circulating levels of leptin and soluble leptin receptor (sOB-R), the free leptin index (FLI), is used as a marker of leptin resistance. Therefore, the aim of our study was to investigate the FLI in mild ...
  • Tumor suppressor role of RBM22 in prostate cancer acting as a dual-factor regulating alternative splicing and transcription of key oncogenic genes
    Jiménez-Vacas, Juan M.; Montero-Hidalgo, Antonio J.; Gómez-Gómez, Enrique; Sáez-Martínez, Prudencio; Fuentes-Fayos, Antonio C.; Closa, Adrià; González-Serrano, Teresa; Martínez-López, Ana; Sánchez-Sánchez, Rafael; López-Casas, Pedro P.; Sarmento-Cabral, André; Olmos, David; Eyras Jiménez, Eduardo; Castaño, Justo P.; Gahete, Manuel D.; Luque, Raul M. (Elsevier, 2023)
    Prostate cancer (PCa) is one of the leading causes of cancer-related deaths among men. Consequently, the identification of novel molecular targets for treatment is urgently needed to improve patients' outcomes. Our group ...

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