Browsing by Author "Casadevall Aguilar, David"

Sort by: Order: Results:

  • Comparison of different methods for defining hyperprogressive disease in NSCLC
    Rocha, Pedro P.; Ramal, Didac; Ripoll, Enric; Moliner, Laura; Corbera-Lloret, Alex; Hardy-Werbin, Max; Orrillo, Mayra; Taus García, Álvaro; Zuccarino, Flavio; Gibert Fernandez, Joan 1988-; Perera Bel, Júlia; Casadevall Aguilar, David; Arriola Aperribay, Edurne (Elsevier, 2020)
    Introduction: Hyperprogressive disease (HPD) as a consequence of immune checkpoint inhibitors in NSCLC has been reported in multiple studies. However, inconsistent results in incidence and survival outcomes within studies, ...
  • Comprehensive analysis of metabolic isozyme targets in cancer
    Marczyk, Michal; Gunasekharan, Vignesh; Casadevall Aguilar, David; Qing, Tao; Foldi, Julia; Sehgal, Raghav; Shan, Naing Lin; Blenman, Kim R.M.; O'Meara, Tess A.; Umlauf, Sheila; Surovtseva, Yulia V.; Muthusamy, Viswanathan; Rinehart, Jesse; Perry, Rachel J.; Kibbey, Richard; Hatzis, Christos; Pusztai, Lajos (American Association for Cancer Research (AACR), 2022)
    Metabolic reprogramming is a hallmark of malignant transformation, and loss of isozyme diversity (LID) contributes to this process. Isozymes are distinct proteins that catalyze the same enzymatic reaction but can have ...
  • Dabrafenib in an elderly patient with metastatic melanoma and BRAF V600R mutation: a case report.
    Casadevall Aguilar, David; Vidal Barrull, Joana; Gallardo Hernández, Fernando; Zuccarino, Flavio; Arumí, Montserrat; Dalmases Massegú, Alba, 1982-; Bellosillo Paricio, Beatriz; Montagut Viladot, Clara (BioMed Central, 2016)
    BACKGROUND: Approximately 50 % of malignant melanomas harbor activating point mutations in the BRAF gene. Typically, these mutations result in the substitution of the amino acid valine at codon 600 of the gene, and 90-95 ...
  • Exploring the association of cancer and depression in electronic health records: combining encoded diagnosis and mining free-text clinical notes
    Leis Machin, Angela; Casadevall Aguilar, David; Albanell Mestres, Joan; Posso, Margarita; Macià Guilà, Francesc Assís; Castells, Xavier; Ramírez Anguita, Juan Manuel; Martínez Roldán, Jordi; Furlong, Laura I., 1971-; Sanz, Ferran; Ronzano, Francesco; Mayer, Miguel Ángel, 1960- (JMIR Publications, 2022)
    Background: A cancer diagnosis is a source of psychological and emotional stress, which are often maintained for sustained periods of time that may lead to depressive disorders. Depression is one of the most common ...
  • Immune microenvironment of triple-negative breast cancer in African-American and Caucasian women
    O’Meara, Tess; Safonov, Anton; Casadevall Aguilar, David; Qing, Tao; Silber, Andrea; Killelea, Brigid; Hatzis, Christos; Pusztai, Lajos (Springer, 2019)
    PURPOSE: African-American (AA) patients with triple-negative breast cancer (TNBC) are less likely to achieve pathologic complete response from neoadjuvant chemotherapy and have poorer prognosis than Caucasian patients with ...
  • Is there a role for epidermal growth factor receptor tyrosine kinase inhibitors in epidermal growth factor receptor wild-type non-small cell lung cancer?
    Arriola Aperribay, Edurne; Taus García, Álvaro; Casadevall Aguilar, David (Baishideng Publishing Group, 2015)
    Non-small cell lung cancer (NSCLC) is the most common type of lung cancer with a world-wide annual incidence of around 1.3 million. The majority of patients are diagnosed with advanced disease and survival remains poor. ...
  • LCOR mediates interferon-independent tumor immunogenicity and responsiveness to immune-checkpoint blockade in triple-negative breast cancer
    Pérez-Núñez, Iván; Rozalén, Catalina; Palomeque, José Ángel; Sangrador, Irene; Dalmau, Mariona; Comerma Blesa, Laura, 1983-; Hernández Prat, Anna, 1984-; Casadevall Aguilar, David; Menendez Romero, Silvia; Liu, Daniel Dan; Berenguer De Felipe, Jordi; Peña Arranz, Raúl, 1976; Montañés, José Carlos; Albà Soler, Mar; Bonnin, Sarah; Ponomarenko, Julia; Servitja Tormo, Sonia; Arribas, Joaquín; Albanell Mestres, Joan; Celià-Terrassa, Toni (Nature Research, 2022)
    Ligand-dependent corepressor (LCOR) mediates normal and malignant breast stem cell differentiation. Cancer stem cells (CSCs) generate phenotypic heterogeneity and drive therapy resistance, yet their role in immunotherapy ...
  • MET expression and copy number heterogeneity in nonsquamous non-small cell lung cancer (nsNSCLC).
    Casadevall Aguilar, David; Gimeno Beltran, Javier; Clavé Safont, Sergi; Taus García, Álvaro; Pijuan Andujar, Lara; Arumí de Dios, Miriam; Lorenzo Perez, Marta; Menendez Romero, Silvia; Cañadas Castillo, Israel, 1984-; Albanell Mestres, Joan; Serrano Figueras, Sergi; Espinet Solà, Blanca; Salido Galeote, Marta; Arriola Aperribay, Edurne (Impact Journals, 2015)
    OBJECTIVE: We aimed to assess MET intratumoral heterogeneity and its potential impact on biomarker-based patient selection as well as potential surrogate biomarkers of MET activation. METHODS: Our study included 120 patients ...
  • mTOR inhibition and T-DM1 in HER2-positive breast cancer
    Casadevall Aguilar, David; Hernández Prat, Anna, 1984-; García-Alonso, Sara; Arpí Llucià, Oriol; Menéndez, Silvia; Qin, Mengjuan; Guardia Valenzuela, Cristina, 1990-; Morancho Armisen, Beatriz; Sánchez-Martín, Francisco Javier; Zazo, Sandra; Gavilán, Elena; Sabbaghi Mehrjardi, Mohammad Ali; Eroles, Pilar; Cejalvo, Juan M.; Lluch, Ana; Rojo, Federico; Pandiella, Atanasio; Rovira, Ana; Albanell Mestres, Joan (American Association for Cancer Research (AACR), 2022)
    In patients with trastuzumab-resistant HER2-positive breast cancer, the combination of everolimus (mTORC1 inhibitor) with trastuzumab failed to show a clinically significant benefit. However, the combination of mTOR ...
  • Quantification and progress over time of specific antibodies against severe acute respiratory syndrome coronavirus 2 in breast milk of lactating women vaccinated with BNT162b2 Pfizer-BioNTech coronavirus disease 2019 vaccine (LacCOVID)
    Esteve Palau, Erika; Gonzalez-Cuevas, Araceli; Guerrero, M. Eugenia; Garcia-Terol, Clara; Alvarez, M. Carmen; García, Geneva; Moreno, Encarna; Medina, Francesc-Xavier; Casadevall Aguilar, David; Diaz-Brito, V. (Oxford University Press, 2022)
    Background: several observational studies demonstrated the passage of postvaccine antibodies through breast milk in women vaccinated against coronavirus disease 2019 (COVID-19), mostly with messenger RNA (mRNA)-based ...
  • Quantification of specific antibodies against SARS-CoV-2 in breast milk of lactating women vaccinated with an mRNA vaccine
    Esteve Palau, Erika; Gonzalez-Cuevas, Araceli; Guerrero, M. Eugenia; Garcia-Terol, Clara; Alvarez, M. Carmen; Casadevall Aguilar, David; Diaz-Brito, V. (American Medical Association, 2021)
    This cohort study assesses the concentration of SARS-CoV-2 antibodies in the breast milk of women who received vaccines for COVID-19 and their correlation with serum antibody levels.
  • The prognostic role of epigenetic dysregulation in bladder cancer: A systematic review
    Casadevall Aguilar, David; Kilian, Anaïs Yacine; Bellmunt Molins, Joaquim, 1959- (Elsevier, 2017)
    BACKGROUND: Despite adequate treatment and follow-up, around one fifth of patients with localized bladder cancer will present with disease progression. Adequate prognostic biomarkers are lacking to define patients who are ...