Browsing by Author "Butnaru, Cristian M."

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  • KChIP3 coupled to Ca2+ oscillations exerts a tonic brake on baseline mucin release in the colon
    Cantero Recasens, Gerard, 1984-; Butnaru, Cristian M.; Valverde, M. A. (Miguel Ángel), 1963-; Naranjo, José R.; Brouwers, Nathalie; Malhotra, Vivek (eLife, 2018)
    Regulated mucin secretion from specialized goblet cells by exogenous agonist-dependent (stimulated) and -independent (baseline) manner is essential for the function of the epithelial lining. Over extended periods, baseline ...
  • New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells
    Bassaganyas Bars, Laia, 1985-; Popa, Stephanie J.; Horlbeck, Max; Puri, Claudia; Stewart, Sarah E.; Campelo, Felix; Ashok, Anupama, 1985-; Butnaru, Cristian M.; Brouwers, Nathalie; Heydari, Kartoosh; Ripoche, Jean; Weissman, Jonathan; Rubinsztein, David C.; Schekman, Randy; Malhotra, Vivek; Moreau, Kevin; Villeneuve, Julien (Rockefeller University Press, 2019)
    Protein and membrane trafficking pathways are critical for cell and tissue homeostasis. Traditional genetic and biochemical approaches have shed light on basic principles underlying these processes. However, the list of ...
  • Novel Dent disease 1 cellular models reveal biological processes underlying ClC-5 loss-of-function
    Durán, Mónica; Burballa Tàrrega, Carla, 1988-; Cantero Recasens, Gerard, 1984-; Butnaru, Cristian M.; Malhotra, Vivek; Ariceta, Gema; Sarró, Eduard; Meseguer, Anna (Oxford University Press, 2021)
    Dent disease 1 (DD1) is a rare X-linked renal proximal tubulopathy characterized by low molecular weight proteinuria and variable degree of hypercalciuria, nephrocalcinosis and/or nephrolithiasis, progressing to chronic ...
  • Sodium channel TRPM4 and sodium/calcium exchangers (NCX) cooperate in the control of Ca2+-induced mucin secretion from goblet cells
    Cantero Recasens, Gerard, 1984-; Butnaru, Cristian M.; Brouwers, Nathalie; Mitrovic, Sandra; Valverde, M. A. (Miguel Ángel), 1963-; Malhotra, Vivek (American Society for Biochemistry and Molecular Biology (ASBMB), 2019)
    Regulated mucin secretion is essential for the formation of the mucus layer that protects the underlying epithelial cells from foreign particles. Alterations in the quantity or quality of secreted mucins are therefore ...