Browsing by Author "Burokas, Aurelijus, 1982-"

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  • Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans
    Mayneris Perxachs, Jordi; Castells-Nobau, Anna; Arnoriaga Rodríguez, María; Garre-Olmo, Josep; Puig, Josep; Ramos, Rafel; Martínez Hernández, Francisco; Burokas, Aurelijus, 1982-; Coll, Clàudia; Moreno-Navarrete, José Maria; Zapata-Tona, Cristina; Pedraza, Salvador; Pérez Brocal, Vicente; Ramió-Torrentà, Lluís; Ricart, Wifredo; Moya, Andrés; Martínez García, Manuel; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (Elsevier, 2022)
    Growing evidence implicates the gut microbiome in cognition. Viruses, the most abundant life entities on the planet, are a commonly overlooked component of the gut virome, dominated by the Caudovirales and Microviridae ...
  • Editorial: gut microbiota as a therapeutic target in neuropsychiatric disorders: current status and future directions
    Cai, Hualin; Chen, Xia; Burokas, Aurelijus, 1982-; Maldonado, Rafael, 1961- (Frontiers, 2023)
  • Epigenetic and proteomic expression changes promoted by eating addictive-like behavior
    Mancino, Samantha, 1987-; Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Gutiérrez Martos, Miriam, 1989-; Martín García, Elena, 1975-; Pucci, Mariangela; Falconi, Anastasia; D'Addario, Claudio; Maccarrone, Mauro; Maldonado, Rafael, 1961- (Nature Publishing Group, 2015)
    An increasing perspective conceptualizes obesity and overeating as disorders related to addictive-like processes that could share common neurobiological mechanisms. In the present study, we aimed at validating an animal ...
  • Extinction and reinstatement of an operant responding maintained by food in different models of obesity
    Burokas, Aurelijus, 1982-; Martín García, Elena, 1975-; Espinosa-Carrasco, José; Erb, Ionas; McDonald, Jerome; Notredame, Cedric; Dierssen, Mara; Maldonado, Rafael, 1961- (Wiley-Blackwell, 2018)
    A major problem in treating obesity is the high rate of relapse to abnormal food-taking habits after maintaining an energy balanced diet. Alterations of eating behavior such as compulsive-like behavior and lack of self-control ...
  • Frustrated expected reward induces differential transcriptional changes in the mouse brain
    Martín García, Elena, 1975-; Fernández Castillo, Noelia; Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Sánchez-Mora, Cristina; Casas, Miguel; Ribasés, Marta; Cormand, Bru; Maldonado, Rafael, 1961- (Wiley, 2015)
    Frustration represents a particular aspect of the addictive process that is related to loss of control when the expected reward is not obtained. We aim to study the consequences of frustrated expected reward on gene ...
  • Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile
    Arnoriaga Rodríguez, María; Mayneris Perxachs, Jordi; Burokas, Aurelijus, 1982-; Pérez Brocal, Vicente; Moya, Andrés; Portero Otín, Manuel; Ricart, Wifredo; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (BioMed Central, 2020)
    Background: The chaperone ClpB, a bacterial protein, is a conformational antigen-mimetic of α-melanocyte-stimulating hormone (α-MSH) implicated in body weight regulation in mice. We here investigated the potential associations ...
  • Gut microbiota signatures of vulnerability to food addiction in mice and humans
    Samulenaite, Solveiga; García Blanco, Alejandra; Mayneris Perxachs, Jordi; Domingo Rodriguez, Laura, 1992-; Cabana-Domínguez, Judit; Fernàndez-Castillo, Noèlia; Gago-García, Edurne; Pineda-Cirera, Laura; Burokas, Aurelijus, 1982-; Espinosa-Carrasco, José; Arboleya, Silvia; Latorre, Jessica; Stanton, Catherine; Hosomi, Koji; Kunisawa, Jun; Cormand, Bru; Fernández Real, Jose M.; Maldonado, Rafael, 1961-; Martín García, Elena, 1975- (BMJ Publishing Group, 2024)
    Objective: Food addiction is a multifactorial disorder characterised by a loss of control over food intake that may promote obesity and alter gut microbiota composition. We have investigated the potential involvement of ...
  • Gut microbiota steroid sexual dimorphism and its impact on gonadal steroids: influences of obesity and menopausal status
    Mayneris Perxachs, Jordi; Arnoriaga Rodríguez, María; Luque-Córdoba, Diego; Priego-Capote, Feliciano; Pérez Brocal, Vicente; Moya, Andrés; Burokas, Aurelijus, 1982-; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (BioMed Central, 2020)
    Background: Gonadal steroid hormones have been suggested as the underlying mechanism responsible for the sexual dimorphism observed in metabolic diseases. Animal studies have also evidenced a causal role of the gut microbiome ...
  • Microbiota alterations in proline metabolism impact depression
    Mayneris Perxachs, Jordi; Martin, Miquel; Burokas, Aurelijus, 1982-; Escrichs, Anira; Deco, Gustavo; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (Elsevier, 2022)
    The microbiota-gut-brain axis has emerged as a novel target in depression, a disorder with low treatment efficacy. However, the field is dominated by underpowered studies focusing on major depression not addressing microbiome ...
  • miRNA signatures associated with vulnerability to food addiction in mice and humans
    García Blanco, Alejandra; Domingo Rodriguez, Laura, 1992-; Cabana-Domínguez, Judit; Fernández-Castillo, Noèlia; Pineda-Cirera, Laura; Mayneris Perxachs, Jordi; Burokas, Aurelijus, 1982-; Espinosa-Carrasco, José; Arboleya, Silvia; Latorre, Jessica; Stanton, Catherine; Cormand, Bru; Fernández Real, Jose M.; Martín-García, Elena; Maldonado, Rafael, 1961- (American Society for Clinical Investigation, 2022)
    Food addiction is characterized by a loss of behavioral control over food intake and is associated with obesity and other eating disorders. The mechanisms underlying this behavioral disorder are largely unknown. We aimed ...
  • Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways
    Arnoriaga Rodríguez, María; Burokas, Aurelijus, 1982-; Ortega Sánchez, Juan Antonio; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (BMJ Publishing Group, 2021)
    Background: Inhibitory control (IC) is critical to keep long-term goals in everyday life. Bidirectional relationships between IC deficits and obesity are behind unhealthy eating and physical exercise habits. Methods: We ...
  • Operant model of frustrated expected reward in mice
    Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (Wiley-Blackwell, 2012)
    One aspect of the addictive process that has not been thoroughly investigated is the consequence of the frustrated state occurring when the drug is not available. The present study aimed to validate a novel operant model ...
  • Sex-dependent psychoneuroendocrine effects of THC and MDMA in an animal model of adolescent drug consumption
    Llorente Berzal, Alvaro; Puighermanal Puigvert, Emma, 1983-; Burokas, Aurelijus, 1982-; Ozaita Mintegui, Andrés, 1969-; Maldonado, Rafael, 1961-; Viveros, Maria Paz (Public Library of Science (PLoS), 2013)
    Ecstasy is a drug that is usually consumed by young people at the weekends and frequently, in combination with cannabis. In the present study we have investigated the long-term effects of administering increasing doses of ...
  • Time-course and dynamics of obesity-related behavioral changes induced by energy-dense foods in mice
    Espinosa-Carrasco, José; Burokas, Aurelijus, 1982-; Fructuoso, Marta; Erb, Ionas; Martín García, Elena, 1975-; Gutiérrez Martos, Miriam, 1989-; Notredame, Cedric; Maldonado, Rafael, 1961-; Dierssen, Mara (Wiley-Blackwell, 2018)
    Obesity represents an important risk factor contributing to the global burden of disease. The current obesogenic environment with easy access to calorie-dense foods is fueling this obesity epidemic. However, how these foods ...

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