Browsing by Author "Burguera, Demián"

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  • Amphioxus functional genomics and the origins of vertebrate gene regulation
    Marlétaz, Ferdinand; Wyatt, Christopher Douglas Robert, 1988-; Burguera, Demián; Marquez, Yamile; Irimia, Manuel (Nature Research, 2018)
    Vertebrates have greatly elaborated the basic chordate body plan and evolved highly distinctive genomes that have been sculpted by two whole-genome duplications. Here we sequence the genome of the Mediterranean amphioxus ...
  • Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes
    Burguera, Demián; Márquez, Yamile; Racioppi, Claudia; Permanyer, Jon; Torres Méndez, Antonio; Esposito, Rosaria; Albuixech Crespo, Beatriz; Fanlo, Lucía; D'Agostino, Ylenia; Gohr, André; Navas Pérez, Enrique; Riesgo, Ana; Cuomo, Claudia; Benvenuto, Giovanna; Christiaen, Lionel A.; Martí, Elisa; D'Aniello, Salvatore; Spagnuolo, Antonietta; Ristoratore, Filomena; Arnone, Maria Ina; García Fernàndez, Jordi; Irimia, Manuel (Nature Publishing Group, 2017)
    Epithelial-mesenchymal interactions are crucial for the development of numerous animal structures. Thus, unraveling how molecular tools are recruited in different lineages to control interplays between these tissues is key ...
  • ExOrthist: a tool to infer exon orthologies at any evolutionary distance
    Márquez, Yamile; Mantica, Federica; Cozzuto, Luca; Burguera, Demián; Hermoso Pulido, Antonio; Ponomarenko, Julia; Roy, Scott W.; Irimia, Manuel (BioMed Central, 2021)
    Several bioinformatic tools have been developed for genome-wide identification of orthologous and paralogous genes. However, no corresponding tool allows the detection of exon homology relationships. Here, we present ...
  • Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain
    Albuixech Crespo, Beatriz; López Blanch, Laura; Burguera, Demián; Maeso, Ignacio; Sánchez Arrones, Luisa; Moreno Bravo, Juan Antonio; Somorjai, Ildikó Maureen Lara; Pascual Anaya, Juan; Puelles, Eduardo; Bovolenta, Paola; García Fernàndez, Jordi; Puelles, Luis; Irimia, Manuel; Ferrán, José Luis E. (Public Library of Science (PLoS), 2017)
    All vertebrate brains develop following a common Bauplan defined by anteroposterior (AP) and dorsoventral (DV) subdivisions, characterized by largely conserved differential expression of gene markers. However, it is still ...
  • The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians
    Spruce, Thomas; Plass Pórtulas, Mireya, 1982-; Gohr, André; Ray, Debashish; Martínez de Lagrán Cabredo, María; Rot, Gregor; Nóvoa, Ana; Burguera, Demián; Permanyer, Jon; Miret-Cuesta, Marta; Zheng, Hong; Swanson, Maurice S.; Morris, Quaid; Mallo, Moises; Dierssen, Mara; Hughes, Timothy R.; Pernaute, Barbara; Irimia, Manuel (Public Library of Science (PLoS), 2022)
    Understanding the regulatory interactions that control gene expression during the development of novel tissues is a key goal of evolutionary developmental biology. Here, we show that Mbnl3 has undergone a striking process ...