Browsing by Author "Brooks, Daniel R."

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  • Climate trends at a hotspot of chronic kidney disease of unknown causes in Nicaragua, 1973-2014
    Petropoulos, Zoe E.; Ramirez Rubio, Oriana; Scammell, Madeleine K.; Laws, Rebecca L.; Lopez-Pilarte, Damaris; Amador, Juan José; Ballester, Joan; O'Callaghan-Gordo, Cristina; Brooks, Daniel R. (MDPI, 2021)
    An ongoing epidemic of chronic kidney disease of uncertain etiology (CKDu) afflicts large parts of Central America and is hypothesized to be linked to heat stress at work. Mortality rates from CKDu appear to have increased ...
  • Metabolic features of increased gut permeability, inflammation, and altered energy metabolism distinguish agricultural workers at risk for mesoamerican nephropathy
    Raines, Nathan H.; Leone, Dominick A.; O'Callaghan-Gordo, Cristina; Ramirez Rubio, Oriana; Amador, Juan José; Lopez Pilarte, Damaris; Delgado, Iris; Leibler, Jessica H.; Embade, Nieves; Gil-Redondo, Rubén; Bruzzone, Chiara; Bizkarguenaga, Maider; Scammell, Madeleine K.; Parikh, Samir M.; Millet, Oscar; Brooks, Daniel R.; Friedman, David J. (MDPI, 2023)
    Mesoamerican nephropathy (MeN) is a form of chronic kidney disease found predominantly in young men in Mesoamerica. Strenuous agricultural labor is a consistent risk factor for MeN, but the pathophysiologic mechanism leading ...
  • Urinary metabolomic profile of youth at risk of chronic kidney disease in Nicaragua
    Hall, Samantha M.; Raines, Nathan H.; Ramirez Rubio, Oriana; Amador, Juan José; López-Pilarte, Damaris; O'Callaghan-Gordo, Cristina; Gil-Redondo, Rubén; Embade, Nieves; Millet, Oscar; Peng, Xiaojing; Vences, Selene; Keogh, Sinead A.; Delgado, Iris; Friedman, David J.; Brooks, Daniel R.; Leibler, Jessica H. (Wolters Kluwer (LWW), 2023)
    Background: CKD of a nontraditional etiology (CKDnt) is responsible for high mortality in Central America, although its causes remain unclear. Evidence of kidney dysfunction has been observed among youth, suggesting that ...

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