Browsing by Author "Brockdorff, Neil"

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  • YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing
    Bowness, Joseph S.; Almeida, Mafalda; Nesterova, Tatyana B.; Brockdorff, Neil (Nature Research, 2024)
    X chromosome inactivation (XCI) in mammals is mediated by Xist RNA which functions in cis to silence genes on a single X chromosome in XX female cells, thereby equalising levels of X-linked gene expression relative to XY ...

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