Browsing by Author "Brüggemann, Holger"

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  • Delivery of a sebum modulator by an engineered skin microbe in mice
    Knödlseder, Nastassia; Fábrega, María José; Santos Moreno, Javier; Manils, Joan; Toloza, Lorena; Marín Vilar, Maria; Fernández Avilés, Cristina; Broadbent, Katrina; Maruotti, Julien; Lemenager, Hélène; Carolis, Carlo; Zouboulis, Christos C.; Soler Prat, Concepció; Lood, Rolf; Brüggemann, Holger; Güell Cargol, Marc, 1982- (Nature Research, 2024)
    Microorganisms can be equipped with synthetic genetic programs for the production of targeted therapeutic molecules. Cutibacterium acnes is the most abundant commensal of the human skin, making it an attractive chassis to ...
  • Safety and efficacy of topically applied selected cutibacterium acnes strains over five weeks in patients with acne vulgaris: an open-label, pilot study
    Koraglan, Ante; Paetzold, Bernhard, 1981-; Pereira de Lima, Joao; Brüggemann, Holger; Tüting, Thomas; Schanze, Denny; Güell Cargol, Marc, 1982-; Gollnick, Harald (Society for Publication of Acta Dermato-Venereologica, 2019)
    Imbalance in skin microflora, particularly related to certain Cutibacterium acnes strains, may trigger acne. Application of non-acne-causing strains to the skin may modulate the skin microbiome and thereby lead to a reduction ...
  • Skin microbiome modulation induced by probiotic solutions
    Paetzold, Bernhard, 1981-; Willis, Jesse R.; Pereira de Lima, Joao; Knödlseder, Nastassia; Brüggemann, Holger; Quist, Sven Roy; Gabaldón Estevan, Juan Antonio, 1973-; Güell Cargol, Marc, 1982- (BioMed Central, 2019)
    Background: The skin is colonized by a large number of microorganisms, most of which are beneficial or harmless. However, disease states of skin have specific microbiome compositions that are different from those of healthy ...

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