Browsing by Author "Boronat Rigol, Anna, 1990-"

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  • A smartphone intervention to promote a sustainable healthy diet: Protocol for a pilot study
    Fresán, Ujué; Bernard, Paquito; Fàbregues Feijóo, Sergi; Boronat Rigol, Anna, 1990-; Araújo Soares, Vera; König, Laura M.; Chevance, Guillaume (JMIR Publications, 2023)
    Background: Changing current dietary patterns into sustainable healthy diets (ie, healthy diets with low environmental impact and socioeconomic fairness) is urgent. So far, few eating behavior change interventions have ...
  • Acetaminophen-induced liver injury alters the Acyl ethanolamine-based anti-inflammatory signaling system in liver
    Rivera, Patricia; Pastor, Antonio; Arrabal, Sergio; Decara, Juan M.; Vargas, Antonio; Sánchez-Marín, Laura; Pavón, Francisco Javier; Serrano, Antonia; Bautista, Dolores; Boronat Rigol, Anna, 1990-; Torre Fornell, Rafael de la; Baixeras, Elena; Lucena, Maria Isabel; Rodríguez de Fonseca, Fernando; Suárez, Juan (Frontiers, 2017)
    Protective mechanisms against drug-induced liver injury are actively being searched to identify new therapeutic targets. Among them, the anti-inflammatory N-acyl ethanolamide (NAE)-peroxisome proliferators activated receptor ...
  • Beer phenolic composition of simple phenols, prenylated flavonoids and alkylresorcinols
    Boronat Rigol, Anna, 1990-; Soldevila-Domenech, Natalia; Rodríguez-Morató, Jose, 1987-; Martínez-Huélamo, Miriam; Lamuela-Raventós, Rosa M.; Torre Fornell, Rafael de la (MDPI, 2020)
    Beer is a fermented beverage with beneficial phenolic compounds and is widely consumed worldwide. The current study aimed to describe the content of three families of phenolic compounds with relevant biological activities: ...
  • Cardiovascular benefits of tyrosol and its endogenous conversion into hydroxytyrosol in humans: a randomized, controlled trial
    Boronat Rigol, Anna, 1990-; Mateus Rodriguez, Julian Andrés; Soldevila-Domenech, Natalia; Guerra, Mercè; Rodríguez-Morató, Jose, 1987-; Varon, Carlota; Muñoz Aguayo, Daniel; Barbosa, Francina; Morales, Juan Carlos; Gaedigk, Andreas; Langohr, Klaus; Covas Planells, Maria Isabel; Pérez Mañá, Clara; Fitó Colomer, Montserrat; Tyndale, Rachel F.; Torre Fornell, Rafael de la (Elsevier, 2019)
    Introduction: The simple phenol hydroxytyrosol (OHTyr) has been associated with the beneficial health effects of extra virgin olive oil. Pre-clinical studies have identified Tyr hydroxylation, mediated by cytochrome P450 ...
  • CYP2D6 and CYP2A6 biotransform dietary tyrosol into hydroxytyrosol.
    Rodríguez-Morató, Jose, 1987-; Robledo, Patricia, 1958-; Tanner, Julie-Anne; Boronat Rigol, Anna, 1990-; Pérez Mañá, Clara; Oliver Chen, CY; Tyndale, Rachel F.; Torre Fornell, Rafael de la (Elsevier, 2016)
    The dietary phenol tyrosol has been reported to be endogenously transformed into hydroxytyrosol, a potent antioxidant with multiple health benefits. In this work, we evaluated whether tyrosine hydroxylase (TH) and cytochrome ...
  • Data on the endogenous conversion of tyrosol into hydroxytyrosol in humans
    Boronat Rigol, Anna, 1990-; Mateus Rodriguez, Julian Andrés; Soldevila-Domenech, Natalia; Guerra Albà, Mercè; Rodríguez-Morató, Jose, 1987-; Varon, Carlota; Muñoz, Daniel; Barbosa, Francina; Morales, Juan Carlos; Gaedigk, Andreas; Langohr, Klaus; Covas Planells, Maria Isabel; Pérez Mañá, Clara; Fitó Colomer, Montserrat; Tyndale, Rachel F.; Torre Fornell, Rafael de la (Elsevier, 2019)
    Here we present new and original data on the endogenous conversion of tyrosol (Tyr) into hydroxytyrosol (OHTyr) in humans and its effects on the cardiovascular system. A randomized, crossover, controlled clinical trial was ...
  • Effects of COVID-19 home confinement on mental health in individuals with increased risk of Alzheimer's disease
    Soldevila-Domenech, Natalia; Forcano, Laura; Boronat Rigol, Anna, 1990-; Lorenzo, Thais; Piera, Iris; Puig Pijoan, Albert; Mateus Rodriguez, Julian Andrés; González de Echávarri, José Maria; Knezevic, Iva; Soteras, Anna; Fauria, Karine; Pizarro Lozano, Mª Nieves; Molinuevo, José Luis; Torre Fornell, Rafael de la; PENSA Study Group (IOS Press, 2021)
    We explored the impact of the Spanish COVID-19 strict home confinement on mental health and cognition in non-infected subjects (N = 16, 60-80 years) diagnosed with subjective cognitive decline and APOEɛ3/ɛ4 carriers. Mental ...
  • Effects of wine and tyrosol on the lipid metabolic profile of subjects at risk of cardiovascular disease: potential cardioprotective role of ceramides
    Rodríguez-Morató, Jose, 1987-; Boronat Rigol, Anna, 1990-; Serreli, Gabriele; Enríquez, Laura; Gómez-Gómez, Àlex; Pozo Mendoza, Óscar J., 1975-; Fitó Colomer, Montserrat; Torre Fornell, Rafael de la (MDPI, 2021)
    Ceramides are a class of sphingolipids which have recently been shown to be better cardiovascular disease (CVD) risk predictors than traditional CVD risk biomarkers. Tyrosol (TYR) is a dietary phenolic compound known to ...
  • Ferulic acid metabolites attenuate LPS-induced inflammatory response in enterocyte-like cells
    Serreli, Gabriele; Naitza, Micaela Rita; Zodio, Sonia; Leoni, Vera Piera; Spada, Martina; Melis, Maria Paola; Boronat Rigol, Anna, 1990-; Deiana, Monica (MDPI, 2021)
    Ferulic acid (FA) is a polyphenol pertaining to the class of hydroxycinnamic acids present in numerous foods of a plant origin. Its dietary consumption leads to the formation of several phase I and II metabolites in vivo, ...
  • Generation of the antioxidant hydroxytyrosol from tyrosol present in beer and red wine in a randomized clinical trial
    Soldevila-Domenech, Natalia; Boronat Rigol, Anna, 1990-; Mateus Rodriguez, Julian Andrés; Diaz-Pellicer, Patricia; Matilla, Iris; Pérez-Otero, Marta; Aldea-Perona, Ana; Torre Fornell, Rafael de la (MDPI, 2019)
    Beer and wine contains the simple phenol tyrosol (TYR) which is endogenously converted into hydroxytyrosol (HT), one of the strongest dietary antioxidants, by CYP2A6 and CYP2D6 polymorphic enzymes. We investigated in humans ...
  • Metabolic disposition and biological significance of simple phenols of dietary origin: hydroxytyrosol and tyrosol
    Rodríguez-Morató, Jose, 1987-; Boronat Rigol, Anna, 1990-; Kotronoulas, Aristotelis; Pujadas Bastardes, Mitona; Pastor, Antonio; Olesti Muñoz, Eulàlia, 1991-; Pérez Mañá, Clara; Khymenets, Olha, 1974-; Fitó Colomer, Montserrat; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Taylor & Francis, 2016)
    Hydroxytyrosol and tyrosol are dietary phenolic compounds present in virgin olive oil and wine. Both compounds are also endogenously synthesized in our body as byproducts of dopamine and tyramine metabolisms, respectively. ...
  • Modulation of Nrf2 by olive oil and wine polyphenols and neuroprotection
    Martínez-Huélamo, Miriam; Rodríguez-Morató, Jose, 1987-; Boronat Rigol, Anna, 1990-; Torre Fornell, Rafael de la (MDPI, 2017)
    Strong adherence to a Mediterranean diet is associated with improved cognitive function and a lower prevalence of mild cognitive impairment. Olive oil and red wine are rich sources of polyphenols which are responsible in ...
  • N-of-1 clinical trials in nutritional interventions directed at improving cognitive function
    Soldevila-Domenech, Natalia; Boronat Rigol, Anna, 1990-; Langohr, Klaus; Torre Fornell, Rafael de la (Frontiers, 2019)
    Longer life expectancy has led to an increase in the prevalence of age-related cognitive decline and dementia worldwide. Due to the current lack of effective treatment for these conditions, preventive strategies represent ...
  • Olive oil phenolic compounds' activity against age-associated cognitive decline: clinical and experimental evidence
    Boronat Rigol, Anna, 1990-; Serreli, Gabriele; Rodríguez-Morató, Jose, 1987-; Deiana, Monica; Torre Fornell, Rafael de la (MDPI, 2023)
    Epidemiological studies have shown that consuming olive oil rich in phenolic bioactive compounds is associated with a lower risk of neurodegenerative diseases and better cognitive performance in aged populations. Since ...
  • Plasma concentrations of oleoylethanolamide in a primary care sample of depressed patients are increased in those treated with selective serotonin reuptake inhibitor-type antidepressants
    Romero Sanchiz, Pablo; Nogueira-Arjona, Raquel; Pastor, Antonio; Araos, Pedro; Serrano, Antonia; Boronat Rigol, Anna, 1990-; García Marchena, Nuria; Mayoral, Fermín; Bordallo, Antonio; Alen, Francisco; Suárez, Juan; Torre Fornell, Rafael de la; Pavón, Francisco Javier; Rodríguez de Fonseca, Fernando (Elsevier, 2019)
    Oleoylethanolamide (OEA) is a non-cannabinoid acylethanolamide with multiple physiological roles that has been proposed to have antidepressant-like activity in preclinical models. OEA shares biosynthetic pathways with ...
  • Prevention of cognitive decline in subjective cognitive decline APOE ε4 carriers after EGCG and a multimodal intervention (PENSA): Study design
    Forcano, Laura; Fauria, Karine; Soldevila-Domenech, Natalia; Minguillón, Carolina; Lorenzo, Thais; Cuenca Royo, Aida Ma, 1981-; Menezes Cabral, Sofia; Pizarro Lozano, Mª Nieves; Boronat Rigol, Anna, 1990-; Molinuevo, José Luis; Torre Fornell, Rafael de la; PENSA Study Group (Wiley, 2021)
    Introduction: Subjects exhibiting subjective cognitive decline (SCD) are at an increased risk for mild cognitive impairment and dementia. Given the delay between risk exposure and disease onset, SCD individuals are ...
  • Protective effect of hydroxytyrosol and tyrosol metabolites in LPS-induced vascular barrier derangement in vitro
    Zodio, Sonia; Serreli, Gabriele; Melis, Maria Paola; Franchi, Benedetta; Boronat Rigol, Anna, 1990-; Torre Fornell, Rafael de la; Deiana, Monica (Frontiers, 2024)
    Introduction: The maintenance of endothelial barrier function is essential for vasal homeostasis and prevention of cardiovascular diseases. Among the toxic stimuli involved in the initiation of atherosclerotic lesions, ...
  • Relationship between sex, APOE genotype, endocannabinoids and cognitive change in older adults with metabolic syndrome during a 3-year Mediterranean diet intervention
    Soldevila-Domenech, Natalia; Fagundo, Beatriz; Cuenca Royo, Aida Ma, 1981-; Forcano, Laura; Gomis González, Maria, 1988-; Boronat Rigol, Anna, 1990-; Pastor, Antonio; Castañer, Olga; Zomeño Fajardo, Maria Dolores; Goday Arno, Alberto; Dierssen, Mara; Baghizadeh Hosseini, Khashayar; Ros, Emilio; Corella, Dolores; Martínez-González, Miguel Ángel, 1957-; Salas Salvadó, Jordi; Fernández Aranda, Fernando; Fitó Colomer, Montserrat; Torre Fornell, Rafael de la (BioMed Central, 2024)
    Background: The Mediterranean diet (MedDiet) has demonstrated efficacy in preventing age-related cognitive decline and modulating plasma concentrations of endocannabinoids (eCBs) and N-acylethanolamines (NAEs, or eCB-like ...
  • Sex differences in endocannabinoids during 3 years of Mediterranean diet intervention: Association with insulin resistance and weight loss in a population with metabolic syndrome
    Soldevila-Domenech, Natalia; Pastor, Antonio; Sala Vila, Aleix; Lázaro, Iolanda; Boronat Rigol, Anna, 1990-; Muñoz, Daniel; Castañer, Olga; Fagundo, Beatriz; Corella, Dolores; Fernández Aranda, Fernando; Martínez-González, Miguel Ángel, 1957-; Salas Salvadó, Jordi; Fitó Colomer, Montserrat; Torre Fornell, Rafael de la (Frontiers, 2022)
    Background: Excess circulating endocannabinoids (eCBs) and imbalanced N-acylethanolamines (NAEs) related eCBs abundance could influence dietary weight loss success. We aimed to examine sex differences in the impact of a ...
  • Wine and olive oil phenolic compounds interaction in humans
    Boronat Rigol, Anna, 1990-; Martínez-Huélamo, Miriam; Cobos Garcia, Ariadna; Torre Fornell, Rafael de la (MDPI, 2018)
    Extra virgin olive oil (EVOO) and red wine (RW) are two basic elements that form part of the so-called Mediterranean diet. Both stand out because of their high phenolic compound content and their potential related health ...

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