Browsing by Author "Bonilla, Félix"

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  • Peláez García, Alberto; Barderas, Rodrigo; Batlle Gómez, Raquel; Viñas Castells, Rosa, 1985-; Bartolome, Rubén A.; Torres, Sofía; Mendes, Marta; López Lucendo, María; Mazzolini, Rocco; Bonilla, Félix; García de Herreros, Antonio; Casal, José Ignacio (American Society for Biochemistry and Molecular Biology (ASBMB), 2015)
    Adipogenesis requires a differentiation program driven by multiple transcription factors, where PPARγ and C/EBPα play a central role. Recent findings indicate that Snail inhibits adipocyte differentiation in 3T3-L1 and ...
  • Herrera, Mercedes; Herrera, Alberto; Domínguez, Gemma; Silva, Javier; García, Vanesa; García, Jose M.; Gómez, Irene; Soldevilla, Beatriz; Muñoz, Concepción; Provencio, Mariano; Campos Martin, Yolanda; García de Herreros, Antonio; Casal, José Ignacio; Bonilla, Félix; Peña, Cristina (Japanese Cancer Association, 2013)
    Tumor epithelial cells within a tumor coexist with a complex microenvironment in which a variety of interactions between its various components determine the behavior of the primary tumors. Cancer-associated fibroblasts ...
  • Martínez-Martínez, Esther; Gómez, Irene; Martín, Paloma; Sánchez, Antonio J.; Román, Laura; Tejerina, Eva; Bonilla, Félix; García Merino, Antonio; García de Herreros, Antonio; Provencio, Mariano; García, Jose M. (Impact Journals, 2015)
    Many studies have demonstrated that the endocannabinoid system (ECS) is altered in different tumor types, including colon cancer. However, little is known about the role of the ECS in tumor progression. Here we report the ...
  • Herrera, Alberto; Herrera, Mercedes; Guerra-Perez, Natalia; Galindo-Pumariño, Cristina; Larriba, María Jesús; García-Barberán, Vanesa; Gil, Beatriz; Giménez-Moyano, Sara; Ferreiro-Monteagudo, Reyes; Veguillas, Pilar; Candia, Antonio; Peña, Raúl; Pinto, Jesús; García-Bermejo, Mª Laura; Muñoz, Alberto; García de Herreros, Antonio; Bonilla, Félix; Carrato, Alfredo; Peña, Cristina (Nature Research, 2018)
    Carcinomas, such as colon cancer, initiate their invasion by rescuing the innate plasticity of both epithelial cells and stromal cells. Although Snail is a transcriptional factor involved in the Epithelial-Mesenchymal ...
  • Peláez García, Alberto; Barderas, Rodrigo; Torres, Sofía; Teixidó, Joaquín; Bonilla, Félix; García de Herreros, Antonio; Hernández-Varas, Pablo; Casal, José Ignacio (Public Library of Science (PLoS), 2013)
    Fibroblast growth factor receptor 4 (FGFR4) is vital in early development and tissue repair. FGFR4 expression levels are very restricted in adult tissues, except in several solid tumors including colorectal cancer, which ...
  • Alba-Castellón, Lorena; Batlle, Raquel; Francí, Clara; Fernández Aceñero, María Jesús; Mazzolini, Rocco; Peña, Raúl; Loubat, Jordina; Alameda Quitllet, Francisco; Rodríguez, Rufo; Curto, Josué; Albanell, Joan; Muñoz, Alberto; Bonilla, Félix; Casal, José Ignacio; Rojo, Federico; García de Herreros, Antonio (Elsevier, 2014)
    Snail1 transcriptional repressor is a major inducer of epithelial-to mesenchymal transition but is very limitedly expressed in adult animals. We have previously demonstrated that Snail1 is required for the maintenance of ...
  • Gómez, Irene; Peña, Cristina; Herrera, Mercedes; Muñoz, Concepción; Larriba, María Jesús; García, Vanesa; Domínguez, Gemma; Silva, Javier; Rodríguez, Rufo; García de Herreros, Antonio; Bonilla, Félix; García, Jose M. (Public Library of Science (PLoS), 2011)
    TWIST1 is a transcription factor that belongs to the family of basic helix-loop-helix proteins involved in epithelial-to-mesenchymal transition and invasion processes. The TWIST1 protein possesses oncogenic, drug-resistant, ...

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