Browsing by Author "Blanco, Enrique"

Sort by: Order: Results:

  • Blanco, Enrique; Farré, Domènec; Albà Soler, Mar; Messeguer, Xavier; Guigó Serra, Roderic (Oxford University Press, 2006)
    Information about the genomic coordinates and the sequence of experimentally identified transcription factor binding sites is found scattered under a variety of diverse formats. The availability of standard collections of ...
  • Pérez-Lluch, Sílvia; Blanco, Enrique; Tilgner, Hagen, 1980-; Curado, Joao; Ruiz-Romero, Marina; Corominas Guiu, Montserrat; Guigó Serra, Roderic (Nature Research, 2015)
    The interplay of active and repressive histone modifications is assumed to have a key role in the regulation of gene expression. In contrast to this generally accepted view, we show that the transcription of genes temporally ...
  • Ruíz Romero, Marina; Blanco, Enrique; Paricio, Nuria; Serras Rigalt, Florenci; Corominas Guiu, Montserrat (EMBO Press, 2015)
    The Drosophila transcription factor Cabut/dTIEG (Cbt) is a growth regulator, whose expression is modulated by different stimuli. Here, we determine Cbt association with chromatin and identify Yorkie (Yki), the transcriptional ...
  • Aranda Aragón, Sergio; Alcaine Colet, Anna; Blanco, Enrique; Borràs, Eva; Caillot, Claire; Sabidó Aguadé, Eduard, 1981-; Di Croce, Luciano (American Association for the Advancement of Science (AAAS), 2019)
    Profiling the chromatin-bound proteome (chromatome) in a simple, direct, and reliable manner might be key to uncovering the role of yet uncharacterized chromatin factors in physiology and disease. Here, we have designed ...
  • Guigó Serra, Roderic; Blanco, Enrique; Pignatelli, Miguel; Punset, Adrià; Pérez-Lluch, Sílvia; Serras Rigalt, Florenci; Corominas Guiu, Montserrat (BioMed Central, 2008)
    BACKGROUND: The trithorax group (trxG) and Polycomb group (PcG) proteins are responsible for the maintenance of stable transcriptional patterns of many developmental regulators. They bind to specific regions of DNA and ...
  • Rinaldi, Lorenzo, 1986-; Datta, Debayan; Serrat, Judit; Morey Ramonell, Lluís; Solanas, Guiomar; Avgustinova, Alexandra; Blanco, Enrique; Pons, José Ignacio; Matallanas, David; Kriegsheim, Alex von; Di Croce, Luciano; Aznar Benitah, Salvador (Elsevier, 2016)
    The genome-wide localization and function of endogenous Dnmt3a and Dnmt3b in adult stem cells are unknown. Here, we show that in human epidermal stem cells, the two proteins bind in a histone H3K36me3-dependent manner to ...
  • Parra Farré, Genís; Blanco, Enrique; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2000)
    GeneID is a program to predict genes in anonymous genomic sequences designed with a hierarchical structure. In the first step, splice sites, and start and stop codons are predicted and scored along the sequence using ...
  • Pascual-Reguant, Laura; Blanco, Enrique; Galan, Silvia; Le Dily, François; Cuartero, Yasmina; Serra-Bardenys, Gemma; Di Carlio, Valerio; Iturbide Martínez de Albéniz, Ane, 1989-; Cebrià i Costa, Joan Pau, 1989-; Nonell Mazelón, Lara; García de Herreros, Antonio; Di Croce, Luciano; Marti-Renom, Marc A.; Peiró Sales, Sandra (Nature Publishing Group, 2018)
    Lamins (A/C and B) are major constituents of the nuclear lamina (NL). Structurally conserved lamina-associated domains (LADs) are formed by genomic regions that contact the NL. Lamins are also found in the nucleoplasm, ...
  • Blanco, Enrique; Guigó Serra, Roderic; Messeguer, Xavier (BioMed Central, 2007)
    Background: The analysis of the promoter sequence of genes with similar expression patterns is/na basic tool to annotate common regulatory elements. Multiple sequence alignments are on the/nbasis of most comparative ...
  • Morey Ramonell, Lluís; Santanach Buxaderas, Alexandra, 1988-; Blanco, Enrique; Aloia, Luigi; Nora, Elphège P.; Bruneau, Benoit G.; Di Croce, Luciano (Elsevier, 2015)
    Polycomb complexes (PRC1 and PRC2) are essential regulators of epigenetic gene silencing in embryonic and adult stem cells. Emerging evidence suggests that the core subunit composition regulates distinct biological processes, ...
  • Santanach Buxaderas, Alexandra, 1988-; Blanco, Enrique; Jiang, Hua; Molloy, Kelly R.; Sansó Martínez, Miriam, 1979-; LaCava, John; Morey Ramonell, Lluís; Di Croce, Luciano (Nature Publishing Group, 2017)
    Polycomb group proteins (PcG) are transcriptional repressors that control cell identity and development. In mammals, five different CBX proteins associate with the core Polycomb repressive complex 1 (PRC1). In mouse embryonic ...
  • Blanco, Enrique; Messeguer, Xavier; Smith, Temple F.; Guigó Serra, Roderic (Public Library of Science (PLoS), 2006)
    We address the problem of comparing and characterizing the promoter regions of genes with similar expression patterns. This remains a challenging problem in sequence analysis, because often the promoter regions of co-expressed ...
  • Erb, Ionas; González-Vallinas Rostes, Juan, 1983-; Bussotti, Giovanni, 1983-; Blanco, Enrique; Eyras Jiménez, Eduardo; Notredame, Cedric (Oxford University Press, 2012)
    We address the challenge of regulatory sequence alignment with a new method, Pro-Coffee, a multiple aligner specifically designed for homologous promoter regions. Pro-Coffee uses a dinucleotide substitution matrix estimated ...