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Browsing by Author "Berrendero Díaz, Fernando, 1971-"
Now showing items 1-20 of 27
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Plaza-Zabala, Ainhoa, 1982-; Flores de los Heros, África, 1985-; Martín García, Elena, 1975-; Saravia Santos, Rocio, 1988-; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Nature Publishing Group, 2013)Hypocretin/orexin signaling is critically involved in relapse to drug-seeking behaviors. In this study, we investigated the involvement of the hypocretin system in the reinstatement of nicotine-seeking behavior induced by ...
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Ten-Blanco, Marc; Flores de los Heros, África, 1985-; Pereda-Pérez, Inmaculada; Piscitelli, Fabiana; Izquierdo-Luengo, Cristina; Cristino, Luigia; Romero, Julián; Hillard, Cecilia J.; Maldonado, Rafael, 1961-; Di Marzo, Vicenzo; Berrendero Díaz, Fernando, 1971- (Elsevier, 2022)Anxiety and stress disorders are often characterized by an inability to extinguish learned fear responses. Orexins/hypocretins are involved in the modulation of aversive memories, and dysregulation of this system may ...
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Plaza-Zabala, Ainhoa, 1982-; Li, Xuan; Milovanovic, Mike; Loweth, Jessica A.; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971-; Wolf, Marina E. (Elsevier, 2013)Hypocretin peptides are critical for the effects of cocaine on excitatory synaptic strength in the ventral tegmental area (VTA). However, little is known about their role in cocaine-induced synaptic plasticity in the nucleus ...
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Saravia Santos, Rocio, 1988-; Ten-Blanco, Marc; Grande, María T.; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2019)Nicotine withdrawal is associated with cognitive deficits including attention, working memory, and episodic memory impairments. These cognitive deficits are a hallmark of nicotine abstinence which could be targeted in order ...
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Berrendero Díaz, Fernando, 1971-; Kieffer, Brigitte L.; Maldonado, Rafael, 1961- (Society for Neuroscience, 2002)The involvement of μ-opioid receptors in different behavioral responses elicited by nicotine was explored by using μ-opioid receptor knock-out mice. The acute antinociceptive responses induced by nicotine in the tail-immersion ...
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Flores de los Heros, África, 1985-; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Frontiers, 2013)Emerging findings suggest the existence of a cross-talk between hypocretinergic and endocannabinoid systems. Although few studies have examined this relationship, the apparent overlap observed in the neuroanatomical ...
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Saravia Santos, Rocio, 1988-; Flores de los Heros, África, 1985-; Plaza-Zabala, Ainhoa, 1982-; Busquets Garcia, Arnau, 1985-; Pastor, Antonio; Torre Fornell, Rafael de la; Di Marzo, Vicenzo; Marsicano, Giovanni; Ozaita Mintegui, Andrés, 1969-; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2017)BACKGROUND: Tobacco withdrawal is associated with deficits in cognitive function, including attention, working memory, and episodic memory. Understanding the neurobiological mechanisms involved in these effects is crucial ...
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Saravia Santos, Rocio, 1988-; Ten-Blanco, Marc; Julià Hernández, Marina; Gagliano, Humberto; Andero, Raül; Armario García, Antonio; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2019)Δ9-tetrahydrocannabinol (THC) consumption during adolescence is reported to be a risk factor for the appearance of psychiatric disorders later in life. The interaction between genetic or environmental events and cannabinoid ...
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Aso Pérez, Ester; Maldonado, Rafael, 1961-; Murtra, Patricia; Balerio, Graciela N.; Berrendero Díaz, Fernando, 1971- (Wiley-Blackwell, 2004)The possible interactions between Delta9-tetrahydrocannabinol (THC) and nicotine remain unclear in spite of the current association of cannabis and tobacco in humans. The aim of the present study was to explore the ...
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Maldonado, Rafael, 1961-; Robledo, Patricia, 1958-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2013)The involvement of the endocannabinoid system in drug addiction was initially studied by the use of compounds with different affinities for each cannabinoid receptor or for the proteins involved in endocannabinoids ...
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Flores de los Heros, África, 1985-; Herry, Cyril; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Oxford University Press, 2017)BACKGROUND: Orexins are hypothalamic neuropeptides recently involved in the regulation of emotional memory. The basolateral amygdala, an area orchestrating fear memory processes, appears to be modulated by orexin transmission ...
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Plaza-Zabala, Ainhoa, 1982-; Flores de los Heros, África, 1985-; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2012)BACKGROUND: Hypocretin (orexin) signaling is involved in drug addiction. In this study, we investigated the role of these hypothalamic neuropeptides in nicotine withdrawal by using behavioral and neuroanatomical approaches. ...
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Plaza-Zabala, Ainhoa, 1982-; Martín García, Elena, 1975-; Lecea, Luis de; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Society for Neuroscience, 2010)Emerging evidence suggests that the hypocretinergic system is involved in addictive behavior. In this study, we investigated the role of these hypothalamic neuropeptides in anxiety-like responses of nicotine and stress-induced ...
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Berrendero Díaz, Fernando, 1971-; Plaza-Zabala, Ainhoa, 1982-; Galeote González, Lola; Flores de los Heros, África, 1985-; Bura, S. Andreea, 1978-; Kieffer, Brigitte L.; Maldonado, Rafael, 1961- (Nature Publishing Group, 2012)Multiple studies in animal models and humans suggest that the endogenous opioid system is an important neurobiological substrate for nicotine addictive properties. In this study, we evaluated the participation of δ-opioid ...
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Plaza-Zabala, Ainhoa, 1982- (Universitat Pompeu Fabra, 2012-11-26)Hypocretin-1 and hypocretin-2, also known as orexin-A and orexin-B, are 2 neuropeptides that are exclusively expressed by a small subset of neurons of the lateral hypothalamic area. Despite their restricted expression ...
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Flores de los Heros, África, 1985-; Julià Hernández, Marina; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Wiley, 2016)BACKGROUND AND PURPOSE: Anatomical, biochemical and pharmacological evidence suggest the existence of a crosstalk between the orexinergic and endocannabinoid systems. While the orexin receptor 1 (OX1 receptor) modulates ...
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Berrendero Díaz, Fernando, 1971-; Robledo, Patricia, 1958-; Trigo i Rodríguez, Josep M.; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (Elsevier, 2010)Nicotine is the primary component of tobacco that maintains the smoking habit and develops addiction. The adaptive changes of nicotinic acetylcholine receptors produced by repeated exposure to nicotine play a crucial role ...
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Berrendero Díaz, Fernando, 1971-; Mendizábal, Victoria; Robledo, Patricia, 1958-; Galeote González, Lola; Bilkei Gorzo, Andras; Zimmer, Andreas; Maldonado, Rafael, 1961- (Society for Neuroscience, 2005)It has been shown previously that the endogenous opioid system may be involved in the behavioral effects of nicotine. In the present study, the participation of endogenous enkephalins on nicotine responses has been ...
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Saravia Santos, Rocio, 1988- (Universitat Pompeu Fabra, 2019-01-10)Cigarette smoking continues to be leading cause of preventable cause of death worldwide. Cognitive modulation by nicotine seems to be a key factor in nicotine addiction. Several studies indicate that initial nicotine intake ...
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Flores de los Heros, África, 1985- (Universitat Pompeu Fabra, 2016-06-22)Orexin-A and orexin-B (also known as hypocretin-1 and hypocretin-2) are two neuropeptides exclusively expressed by a small subpopulation of neurons located within the lateral hypothalamic area. These neuromodulators were ...
Now showing items 1-20 of 27
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