Browsing by Author "Benito Villabriga, Begoña"

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  • Aging impairs reverse remodeling and recovery of ventricular function after isoproterenol-induced cardiomyopathy
    Yáñez Bisbe, Laia, 1993-; Garcia-Elias Heras, Anna; Tajes Orduña, Marta; Almendros, Isaac; Rodríguez-Sinovas, Antonio; Inserte, Javier; Ruiz-Meana, Marisol; Farré, Ramon; Farré López, Núria; Benito Villabriga, Begoña (MDPI, 2022)
    Information about heart failure with reduced ejection fraction (HFrEF) in women and the potential effects of aging in the female heart is scarce. We investigated the vulnerability to develop HFrEF in female elderly mice ...
  • Atrial fibrillation in heart failure is associated with high levels of circulating microRNA-199a-5p and 22-5p and a defective regulation of intracellular calcium and cell-to-cell communication
    Garcia-Elias Heras, Anna; Tajes Orduña, Marta; Yañez Bisbe, Laia; Enjuanes Grau, Cristina; Comín Colet, Josep; Serra, Selma A.; Fernández-Fernández, José Manuel, 1967-; Aguilar-Agon, Kathryn W.; Reilly, Svetlana; Martí Almor, Julio; Benito Villabriga, Begoña (MDPI, 2021)
    MicroRNAs (miRNAs) participate in atrial remodeling and atrial fibrillation (AF) promotion. We determined the circulating miRNA profile in patients with AF and heart failure with reduced ejection fraction (HFrEF), and its ...
  • Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams-Beuren syndrome
    Navarro Romero, Alba, 1990-; Galera López, Lorena, 1993-; Ortiz Romero, Paula, 1994-; Llorente-Ovejero, Alberto; Los Reyes-Ramírez, Lucía de; Bengoetxea de Tena, Iker; Garcia-Elias Heras, Anna; Mas-Stachurska, Aleksandra; Reixachs i Solé, Marina; Pastor, Antonio; Torre Fornell, Rafael de la; Maldonado, Rafael, 1961-; Benito Villabriga, Begoña; Eyras Jiménez, Eduardo; Rodríguez-Puertas, Rafael; Campuzano Uceda, María Victoria; Ozaita Mintegui, Andrés, 1969- (eLife, 2022)
    Williams-Beuren syndrome (WBS) is a rare genetic multisystemic disorder characterized by mild-to-moderate intellectual disability and hypersocial phenotype, while the most life-threatening features are cardiovascular ...
  • Chronic sleep fragmentation mimicking sleep apnea does not worsen left-ventricular function in healthy and heart failure mice
    Cabrera-Aguilera, Ignacio; Benito Villabriga, Begoña; Tajes Orduña, Marta; Farré, Ramon; Gozal, David; Almendros, Isaac; Farré López, Núria (Frontiers, 2020)
    Aims: Obstructive sleep apnea (OSA) has been associated with heart failure (HF). Sleep fragmentation (SF), one of the main hallmarks of OSA, induces systemic inflammation, oxidative stress and sympathetic activation, hence ...
  • Comprehensive genetic characterization of a Spanish Brugada Syndrome cohort
    Selga, Elisabet; Campuzano, Oscar; Pinsach-Abuin, Mellina; Pérez-Serra, Alexandra; Mademont-Soler, Irene; Riuró, Helena; Picó, Ferran; Coll, Mònica; Iglesias, Anna; Pagans, Sara; Sarquella-Brugada, Georgia; Berne, Paola; Benito Villabriga, Begoña; Brugada, Josep; Porres, José M.; López Zea, Matilde; Castro-Urda, Víctor; Fernández-Lozano, Ignacio; Brugada, Ramón (Public Library of Science, 2015)
    BACKGROUND: Brugada syndrome (BrS) is a rare genetic cardiac arrhythmia that can lead to sudden cardiac death in patients with a structurally normal heart. Genetic variations in SCN5A can be identified in approximately ...
  • Defining quantification methods and optimizing protocols for microarray hybridization of circulating microRNAs
    Garcia-Elias Heras, Anna; Alloza, Leonor; Puigdecanet Riubugent, Eulàlia; Nonell Mazelón, Lara; Tajes Orduña, Marta; Curado, Joao; Enjuanes Grau, Cristina; Díaz, Oscar; Bruguera-Cortada, Jordi; Martí-Almor, Julio; Comín Colet, Josep; Benito Villabriga, Begoña (Nature Publishing Group, 2017)
    MicroRNAs (miRNAs) have emerged as promising biomarkers of disease. Their potential use in clinical practice requires standardized protocols with very low miRNA concentrations, particularly in plasma samples. Here we tested ...
  • Ion Channel Disorders and Sudden Cardiac Death
    Garcia-Elias Heras, Anna; Benito Villabriga, Begoña (MDPI, 2018)
    Long QT syndrome, short QT syndrome, Brugada syndrome and catecholaminergic polymorphic ventricular tachycardia are inherited primary electrical disorders that predispose to sudden cardiac death in the absence of structural ...
  • Left atrium assessment by speckle tracking echocardiography in cryptogenic stroke: seeking silent atrial fibrillation
    Ble, Mireia; Benito Villabriga, Begoña; Cuadrado-Godia, Elisa; Pérez-Fernández, Silvia; Gómez Pérez, Miguel Angel; Mas Stachurska, Aleksandra; Tizón-Marcos, Helena; Molina Ferragut, Luis; Martí-Almor, Julio; Cladellas Capdevila, M.Mercedes (MDPI, 2021)
    Silent atrial fibrillation (AF) may be the cause of some cryptogenic strokes (CrS). The aim of the study was to analyse atrial size and function by speckle tracking echocardiography in CrS patients to detect atrial disease. ...
  • Long-term Impact of Continuous Positive Airway Pressure Therapy on Arrhythmia and Heart Rate Variability in Patients With Sleep Apnea.
    Grau Sanmartí, Nuria; Bazán, Víctor; Kallouchi, Mohamed; Rodríguez, Diego; Estirado Vera, Cristina, 1968-; Corral Celma, María Isabel; Valls Córdoba, Maria Teresa; Ramos Ardanaz, Pablo; Sanjuas Benito, Carlos; Félez Flor, Miguel Ángel; Vallés Gras, Ermengol; Benito Villabriga, Begoña; Gea Guiral, Joaquim; Bruguera-Cortada, Jordi; Martí-Almor, Julio (Elsevier, 2016)
    INTRODUCTION: Autonomic dysfunction can alter heart rate variability and increase the incidence of arrhythmia. We analyzed the impact of continuous positive airway pressure (CPAP) on this pathophysiological phenomenon in ...
  • Not enough QRS shortening? Keep calm and add another lead
    Jiménez-López, Jesús; Vallés Gras, Ermengol; Alcalde Rodríguez, Oscar; Benito Villabriga, Begoña; Cabrera Gómez, Sandra; Martí-Almor, Julio (OMICS International, 2016)
    Cardiac resynchronization therapy (CRT) diminishes symptoms and reduces hospitalization and mortality in patients with heart failure, LV dysfunction and left bundle branch block. However, up to one third of patients do not ...
  • Post-ictal atrial fibrillation detected during video-EEG monitoring: Case report, proposed physiopathologic mechanism and therapeutic considerations
    Sanchez-Larsen, Alvaro; Aznar Laín, Gemma; Benito Villabriga, Begoña; Principe, Alessandro; Ley Nacher, Miguel; Tauste Campo, Adrià, 1982-; Rocamora, Rodrigo (Elsevier, 2017)
    Cardiac arrhythmias are a frequent complication related to seizures [1]. Most are benign although some, such as high-grade atrioventricular block, asystole, atrial fibrillation (AF), and ventricular fibrillation are ...
  • Role of TRPV4 channels in adverse cardiac remodelling
    Yáñez Bisbe, Laia, 1993- (2022-03-09)
    Els mecanismes que determinen el desenvolupament de remodelat cardíac, tant en la seva forma adversa (característica de la insuficiència cardíaca), com adaptativa (induïda per exercici), no es coneixen en detall. Els ...
  • The conventional isoproterenol-induced heart failure model does not consistently mimic the diaphragmatic dysfunction observed in patients
    Cabrera-Aguilera, Ignacio; Falcones, Bryan; Calvo-Fernández, Alicia; Benito Villabriga, Begoña; Barreiro Portela, Esther; Gea Guiral, Joaquim; Farré, Ramon; Almendros, Isaac; Farré López, Núria (Public Library of Science (PLoS), 2020)
    Heart failure (HF) impairs diaphragm function. Animal models realistically mimicking HF should feature both the cardiac alterations and the diaphragmatic dysfunction characterizing this disease. The isoproterenol-induced ...
  • Ultra-early continuous cardiac monitoring improves atrial fibrillation detection and prognosis of patients with cryptogenic stroke
    Cuadrado-Godia, Elisa; Benito Villabriga, Begoña; Ois Santiago, Angel Javier; Vallés Gras, Ermengol; Rodríguez-Campello, Ana; Giralt-Steinhauer, Eva; Cabrera Gómez, Sandra; Alcalde Rodríguez, Oscar; Jiménez-López, Jesús; Jiménez Conde, Jordi; Martí-Almor, Julio; Roquer, Jaume (Wiley, 2010)
    Background and purpose: Subclinical atrial fibrillation (AF) is known to underlie a number of cases of cryptogenic stroke (CrS). However, there is need to define the most effective strategy for AF detection. The diagnostic ...