Browsing by Author "Benisty, Hannah, 1986-"

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  • Ghose, Ritobrata; Aranguren-Ibáñez, Álvaro; Arecco, Niccolò; Balboa, Diego; Bataller, Marc; Beltran, Sergi; Benisty, Hannah, 1986-; Bénard, Angèle; Bernardo, Edgar; Carbonell Sala, Silvia; Casals, Eloi; Ciampi, Ludovica; Condemi, Livia; Corvò, Alberto; Cosín-Tomás, Marta; Cuenca-Ardura, Mirabai; Duran Serrano, Juan Manuel; Espejo Díaz, María Isabel; Fernández Callejo, Marcos; Gañez-Zapater, Antoni; Garcia-Castellanos, Raquel; Garrido, Romina; Henkin, Gil; Hermoso Pulido, Antonio; Hernandez-Alias, Xavier; Herrero Vicente, Jorge; Ingham, Matthew; Lim, Wei Ming; Llonch, Sílvia; Marmesat Bertoli, Elena; Miguel Escalada, Irene; Montero-Blay, Ariadna; Navarrete Hernández, Cristina; Neguembor, Maria Victoria; Ní Chárthaigh, Róisín-Ana; Pardo-Lorente, Natalia; Pascual-Reguant, Laura, 1990-; Pérez-Lluch, Sílvia; Perza, Reyes; Pesaresi, Martina, 1991-; Picó Amado, Daniel; Pifarré, Paula; Piscia, Davide; Plana-Carmona, Marcos; Ponomarenko, Julia; Radusky, Leandro; Rivero, Ezequiel; Rogalska, Malgorzata; Torcal Garcia, Guillem, 1991-; Wojnacki, José (F1000Research, 2020)
    The COVID-19 pandemic has posed and is continuously posing enormous societal and health challenges worldwide. The research community has mobilized to develop novel projects to find a cure or a vaccine, as well as to ...
  • Stojanovski, Klement; Ferrar, Tony; Benisty, Hannah, 1986-; Uschner, Friedemann; Delgado Blanco, Javier; Jimenez, Javier; Solé, Carme; Nadal Clanchet, Eulàlia de; Klipp, E., 1965-; Posas Garriga, Francesc; Serrano Pubull, Luis, 1982-; Kiel, Christina (Elsevier, 2017)
    The understanding of interaction dynamics in signaling pathways can shed light on pathway architecture and provide insights into targets for intervention. Here, we explored the relevance of kinetic rate constants of a key ...
  • Benisty, Hannah, 1986-; Weber, Marc; Hernandez-Alias, Xavier; Schaefer, Martin H.; Serrano Pubull, Luis, 1982- (National Academy of Sciences, 2020)
    It is well known that in cancer gene families some members are more frequently mutated in tumor samples than their family counterparts. A paradigmatic case of this phenomenon is KRAS from the RAS family. Different explanations ...
  • Benisty, Hannah, 1986- (Universitat Pompeu Fabra, 2019-12-13)
    The RAS oncogenes KRAS, NRAS and HRAS are mutated in one third of human cancers where they exhibit different mutation patterns. A potential factor contributing to this mutation bias is the variation of RAS expression ...
  • Unal, E. Besray; Kiel, Christina; Benisty, Hannah, 1986-; Campbell, Andrew; Pickering, Karen; Blüthgen, Nils; Sansom, Owen J.; Serrano Pubull, Luis, 1982- (BioMed Central, 2018)
    Background: Proteins of the ubiquitously expressed core proteome are quantitatively correlated across multiple eukaryotic species. In addition, it was found that many protein paralogues exhibit expression anticorrelation, ...
  • Kiel, Christina; Benisty, Hannah, 1986-; Lloréns Rico, Verónica, 1989-; Serrano Pubull, Luis, 1982- (eLife, 2016)
    Many driver mutations in cancer are specific in that they occur at significantly higher rates than - presumably - functionally alternative mutations. For example, V600E in the BRAF hydrophobic activation segment (AS) pocket ...
  • Hernandez-Alias, Xavier; Benisty, Hannah, 1986-; Schaefer, Martin H.; Serrano Pubull, Luis, 1982- (Cell Press, 2021)
    Viruses need to hijack the translational machinery of the host cell for a productive infection to happen. However, given the dynamic landscape of tRNA pools among tissues, it is unclear whether different viruses infecting ...
  • Hernandez-Alias, Xavier; Benisty, Hannah, 1986-; Schaefer, Martin H.; Serrano Pubull, Luis, 1982- (Wiley-VCH Verlag, 2020)
    Different tissues express genes with particular codon usage and anticodon tRNA repertoires. However, the codon-anticodon co-adaptation in humans is not completely understood, nor is its effect on tissue-specific protein ...
  • Beltran-Sastre, Violeta; Benisty, Hannah, 1986-; Burnier, Julia; Berger, Imre; Serrano Pubull, Luis, 1982-; Kiel, Christina (Nature Research, 2015)
    Understanding the quantitative functional consequences of human disease mutations requires silencing of endogenous genes and expression of mutants at close to physiological levels. Changing protein levels above or below ...
  • Hernandez-Alias, Xavier; Benisty, Hannah, 1986-; Radusky, Leandro; Serrano Pubull, Luis, 1982-; Schaefer, Martin H. (BioMed Central, 2023)
    Background: Codon usage and nucleotide composition of coding sequences have profound effects on protein expression. However, while it is recognized that different tissues have distinct tRNA profiles and codon usages in ...

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