Browsing by Author "Benisty, Hannah"

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  • Stojanovski, Klement; Ferrar, Tony; Benisty, Hannah; Uschner, Friedemann; Delgado Blanco, Javier; Jimenez, Javier; Solé, Carme; Nadal Clanchet, Eulàlia de; Klipp, E., 1965-; Posas Garriga, Francesc; Serrano Pubull, Luis, 1982-; Kiel, Christina (Elsevier, 2017)
    The understanding of interaction dynamics in signaling pathways can shed light on pathway architecture and provide insights into targets for intervention. Here, we explored the relevance of kinetic rate constants of a key ...
  • Unal, E. Besray; Kiel, Christina; Benisty, Hannah; Campbell, Andrew; Pickering, Karen; Blüthgen, Nils; Sansom, Owen J.; Serrano Pubull, Luis, 1982- (BioMed Central, 2018)
    Background: Proteins of the ubiquitously expressed core proteome are quantitatively correlated across multiple eukaryotic species. In addition, it was found that many protein paralogues exhibit expression anticorrelation, ...
  • Kiel, Christina; Benisty, Hannah; Lloréns Rico, Verónica, 1989-; Serrano Pubull, Luis, 1982- (eLife, 2016)
    Many driver mutations in cancer are specific in that they occur at significantly higher rates than - presumably - functionally alternative mutations. For example, V600E in the BRAF hydrophobic activation segment (AS) pocket ...