Browsing by Author "Benevolenskaya, Elizaveta V."

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  • Islam, Abul, 1978-; Richter, William F.; Jacobs, Laura A.; López Bigas, Núria; Benevolenskaya, Elizaveta V. (Public Library of Science (PLoS), 2011)
    Cancer is characterized by aberrant patterns of expression of multiple genes. These major shifts in gene expression are believed to be due to not only genetic but also epigenetic changes. The epigenetic changes are ...
  • Islam, Abul (Universitat Pompeu Fabra, 2012-10-10)
    Recent advances in high throughput technology have opened the door to systematic studies of epigenetic mechanisms. One of the key components in the regulation of the cell cycle and differentiation is the retinoblastoma ...
  • Beshiri, Michael L.; Islam, Abul, 1978-; DeWaal, Dannielle C.; Richter, William F.; Love, Jennifer; López Bigas, Núria; Benevolenskaya, Elizaveta V. (MYJoVE Corporation, 2010)
    Recruitment of transcriptional and epigenetic factors to their targets is a key step in their regulation. Prominently featured in recruitment are the protein domains that bind to specific histone modifications. One such ...
  • Váraljai, Renáta; Islam, Abul, 1978-; Beshiri, Michael L.; Rehman, Jalees; López Bigas, Núria; Benevolenskaya, Elizaveta V. (Cold Spring Harbor Laboratory Press (CSHL Press), 2015)
    The retinoblastoma tumor suppressor protein pRb restricts cell growth through inhibition of cell cycle progression. Increasing evidence suggests that pRb also promotes differentiation, but the mechanisms are poorly understood, ...
  • Ambrus, Aaron M.; Islam, Abul, 1978-; Holmes, Katherine B.; Moon, Nam Sung; López Bigas, Núria; Benevolenskaya, Elizaveta V.; Frolov, Maxim V. (Elsevier, 2013)
    E2F/DP transcription factors regulate cell proliferation and apoptosis. Here, we investigated the mechanism of the resistance of Drosophila dDP mutants to irradiation-induced apoptosis. Contrary to the prevailing view, ...
  • López Bigas, Núria; Kisiel, Tomasz A.; DeWaal, Dannielle C.; Holmes, Katherine B.; Volkert, Tom L.; Gupta, Sumeet; Love, Jennifer; Murray, Heather L.; Young, Richard A.; Benevolenskaya, Elizaveta V. (Universitat Pompeu Fabra, 2008-09)
    Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation.

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