Browsing by Author "Bauer, Moritz, 1987-"

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  • Causality in transcription and genome folding: Insights from X inactivation
    Bauer, Moritz, 1987-; Payer, Bernhard, 1975-; Filion, Guillaume (Wiley, 2022)
    The spatial organization of genomes is becoming increasingly understood. In mammals, where it is most investigated, this organization ties in with transcription, so an important research objective is to understand whether ...
  • Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation
    Bauer, Moritz, 1987-; Vidal, Enrique; Zorita, Eduard; Üresin, Nil; Pinter, Stefan F.; Filion, Guillaume; Payer, Bernhard, 1975- (Nature Research, 2021)
    A hallmark of chromosome organization is the partition into transcriptionally active A and repressed B compartments, and into topologically associating domains (TADs). Both structures were regarded to be absent from the ...
  • Controlled X-chromosome dynamics defines meiotic potential of female mouse in vitro germ cells
    Severino, Jacqueline, 1990-; Bauer, Moritz, 1987-; Mattimoe, Tom; Arecco, Niccolò; Cozzuto, Luca; Lorden, Patricia; Hamada, Norio; Nosaka, Yoshiaki; Nagaoka, So I.; Audergon, Pauline; Tarruell Pellegrin, Antonio,1990-; Heyn, Holger; Hayashi, Katsuhiko; Saitou, Mitinori; Payer, Bernhard, 1975- (EMBO Press, 2022)
    The mammalian germline is characterized by extensive epigenetic reprogramming during its development into functional eggs and sperm. Specifically, the epigenome requires resetting before parental marks can be established ...
  • Integrative analysis of X-chromosome reactivation kinetics in a novel reprogramming system
    Bauer, Moritz, 1987- (Universitat Pompeu Fabra, 2020-02-14)
    The reactivation of the inactive X chromosome has the potential to provide a unique system to study the developmentally induced formation of euchromatin. However, insights into this process were hampered by the lack of ...