Browsing by Author "Barrios Barrera, Clara"

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  • Anti-myeloperoxidase and proteinase 3 antibodies for nephritis flare prediction in ANCA-associated-vasculitis
    Rodríguez, Eva; Latzke, Belén; Sierra Carpio, Milagros; Romera, Ana María; Siedel, Diego; Agraz, Irene; Soler, María José; García Carro, Clara; Draibe, Juliana; Prada, Francisco José de la; Villacorta, Javier; Buxeda, Anna; Sierra Ochoa, Adriana; Lozano, Inés; Durán, Xavier; Barrios Barrera, Clara; Pascual, Julio (Pascual Santos); Spanish Group for the Study of Glomerular Diseases (GLOSEN) (Oxford University Press, 2022)
    Background: The value of myeloperoxidase and proteinase 3 antibodies titers in the assessment of renal disease activity and flare prediction in patients with ANCA-associated-vasculitis (AAV) is not well-known. Methods: ...
  • Bloqueo del sistema renina-angiotensina-aldosterona en pacientes con enfermedad renal diabética avanzada
    Bermejo García, Sheila; García, Carles Oriol; Rodríguez García, Eva; Barrios Barrera, Clara; Otero, Sol; Mojal, Sergio; Pascual Santos, Julio; Soler, María José (Elsevier, 2018)
    BACKGROUND AND OBJECTIVES: Diabetic kidney disease is the leading cause of end-stage chronic kidney disease. The renin-angiotensin-aldosterone system (RAAS) blockade has been shown to slow the progression of diabetic kidney ...
  • Characteristics of patients with heart failure and advanced chronic kidney disease (Stages 4–5) not undergoing renal replacement therapy (ERCA-IC Study)
    Valdivielso Moré, Sandra; Vicente Elcano, Miren; García Alonso, Anna; Pascual Sanchez, Sergi; Galceran Herrera, Isabel; Barbosa Puig, Francisco; Belarte Tornero, Laia Carla; Ruiz-Bustillo, Sonia; Morales Murillo, Ronald Octavio; Barrios Barrera, Clara; Vime-Jubany, Joan; Farré López, Núria (MDPI, 2023)
    Despite the frequent coexistence of heart failure (HF) in patients with advanced chronic kidney disease (CKD), it has been understudied, and little is known about its prevalence and prognostic relevance. A retrospective ...
  • Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations
    Barrios Barrera, Clara; Otero, Sol; Rodríguez García, Eva; Pedro-Botet, Juan Carlos; Pascual Santos, Julio; Menni, Cristina (Nature Research, 2018)
    Using targeted NMR spectroscopy of 227 fasting serum metabolic traits, we searched for novel metabolic signatures of renal function in 926 type 2 diabetics (T2D) and 4838 non-diabetic individuals from four independent ...
  • Clinical profiles in renal patients with COVID-19
    Arenas Jiménez, María Dolores; Crespo Barrio, Marta; Pérez-Sáez, María José; Collado Nieto, Silvia; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Barbosa Puig, Francisco; Buxeda, Anna; Burballa Tàrrega, Carla, 1988-; Sans Atxer, Laia; Vázquez, Susana; Oliveras, Anna; Mir, Marisa; Outón González, Sara; Galceran Herrera, Isabel; Solà Porta, Eulàlia; Sierra Ochoa, Adriana; Barrios Barrera, Clara; Rodriguez García, Eva; Cao Baduell, Higinio (MDPI, 2020)
    The COVID-19 pandemic has led to frequent referrals to the emergency department on suspicion of this infection in maintenance hemodialysis (MHD) and kidney transplant (KT) patients. We aimed to describe their clinical ...
  • COVID-19 in elderly kidney transplant recipients
    Crespo Barrio, Marta; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Burballa Tàrrega, Carla, 1988-; Vázquez, Susana; Mir, Marisa; Sierra Ochoa, Adriana; Collado Nieto, Silvia; Barrios Barrera, Clara; Rodriguez García, Eva; Sans Atxer, Laia; Barbosa Puig, Francisco; Cao Baduell, Higinio; Arenas Jiménez, María Dolores; Güerri Fernández, Roberto; Horcajada Gallego, Juan Pablo; Pascual Santos, Julio (Wiley, 2020)
    The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 ...
  • COVID-19 in grade 4-5 chronic kidney disease patients
    Collado Nieto, Silvia; Arenas Jiménez, María Dolores; Barbosa Puig, Francisco; Cao Baduell, Higinio; Montero, Maria Milagro; Villar García, Judit; Barrios Barrera, Clara; Rodriguez García, Eva; Sans Atxer, Laia; Sierra Ochoa, Adriana; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Coca, Armando; Maiques Llácer, José María; Güerri Fernández, Roberto; Horcajada Gallego, Juan Pablo; Crespo Barrio, Marta; Pascual Santos, Julio (Karger (S. Karger AG), 2020)
    Introduction: Chronic kidney disease (CKD) increases the risk of mortality during coronavirus disease 2019 (COVID-19) episodes, and some reports have underlined the high incidence and severity of this infection in dialysis ...
  • Effect of immunosuppressive treatments on kidney outcomes after gross hematuria-related acute kidney injury in older patients with IgA nephropathy
    Sevillano Prieto, Ángel M.; Barrios Barrera, Clara; Rodríguez García, Eva; Spanish Group for the Study of Glomerular Diseases (GLOSEN) (Elsevier, 2023)
    Introduction: Macroscopic hematuria (MH) bouts, frequently accompanied by acute kidney injury (AKI-MH) are one of the most common presentations of IgA nephropathy (IgAN) in the elderly. Immunosuppressive therapies are used ...
  • Effects of environmental factors on severity and mortality of COVID-19
    Kifer, Domagoj; Villar García, Judit; Posso, Margarita; Horcajada Gallego, Juan Pablo; Castells, Xavier; Pascual, Julio (Pascual Santos); Barrios Barrera, Clara; Lauc, Gordan (Frontiers, 2021)
    Background: Most respiratory viruses show pronounced seasonality, but for SARS-CoV-2, this still needs to be documented. Methods: We examined the disease progression of COVID-19 in 6,914 patients admitted to hospitals in ...
  • Endothelial ADAM17 expression in the progression of kidney injury in an obese mouse model of pre-diabetes
    Palau González, Vanesa; Jarrín, Josué; Villanueva, Sofia; Benito, David; Márquez, Eva; Rodríguez, Eva; Soler, María José; Oliveras, Anna; Gimeno, Javier; Sans Atxer, Laia; Crespo Barrio, Marta; Pascual Santos, Julio; Barrios Barrera, Clara; Riera Oliva, Marta (MDPI, 2021)
    Disintegrin and metalloproteinase domain 17 (ADAM17) activates inflammatory and fibrotic processes through the shedding of various molecules such as Tumor Necrosis Factor-α (TNF-α) or Transforming Growht Factor-α (TGF-α). ...
  • Factores predictivos de nefropatía no diabética en pacientes diabéticos. Utilidad de la biopsia renal
    Bermejo García, Sheila; Soler, María José; Gimeno Beltran, Javier; Barrios Barrera, Clara; Rodríguez, Eva; Mojal, Sergio; Pascual Santos, Julio (Sociedad Española de Nefrologia, 2016)
    Antecedentes y objetivos: La afectación renal del diabético solo puede determinarse mediante biopsia renal, que presenta una elevada prevalencia de lesiones no diabéticas. Los objetivos del estudio fueron determinar la ...
  • Gut-Microbiota-Metabolite Axis in Early Renal Function Decline.
    Barrios Barrera, Clara; Beaumont, Michelle; Pallister, Tess; Villar García, Judit; Goodrich, Julia K.; Clark, Andrew; Pascual Santos, Julio; Ley, Ruth E.; Spector, Tim D.; Bell, Jordana T.; Menni, Cristina (Public Library of Science, 2015)
    INTRODUCTION: Several circulating metabolites derived from bacterial protein fermentation have been found to be inversely associated with renal function but the timing and disease severity is unclear. The aim of this study ...
  • Impact of recurrent acute kidney injury on patient outcomes
    Rodriguez García, Eva; Arias Cabrales, Carlos Enrique; Bermejo García, Sheila; Sierra Ochoa, Adriana; Burballa Tàrrega, Carla, 1988-; Soler, María José; Barrios Barrera, Clara (Karger (S. Karger AG), 2018)
    BACKGROUND/AIMS: Recurrent acute kidney injury (AKI) is common among patients after a first hospitalized AKI. However, little is known about the prognosis of recurrent AKI episodes in chronic kidney disease (CKD) development, ...
  • Membrane attack complex and factor H in humans with acute kidney injury
    Rodriguez García, Eva; Gimeno Beltran, Javier; Arias Cabrales, Carlos Enrique; Barrios Barrera, Clara; Redondo Pachón, María Dolores; Soler, María José; Crespo Barrio, Marta; Sierra Ochoa, Adriana; Riera Oliva, Marta; Pascual Santos, Julio (Karger (S. Karger AG), 2018)
    BACKGROUND AND AIMS: Complement system seems to play an important role in the pathogenesis of Acute Kidney Injury (AKI). The aim of this study was to investigate the role of complement system in the pathogenesis of human ...
  • Podocytopathy in patients with monoclonal gammopathy: three patients and literature review
    Ribas Closa, Andrés; Puche Gallego, Adrián; Gimeno, Javier; Sans Atxer, Laia; Barrios Barrera, Clara; Márquez, Eva; Naranjo‐Hans, Dolores; Lloveras Rubio, Belen; Lop Gros, Joan; Ramos, Natàlia; Soler, María José; Gabaldon, Alejandra; Crespo Barrio, Marta; Rodríguez, Eva (Oxford University Press, 2021)
    Background: renal manifestations of monoclonal gammopathies are of increasing interest among nephrologists. Typical manifestations include light chain cast nephropathy, amyloidosis or renal damage mediated by monoclonal ...
  • Predictive metabolites for incident myocardial infarction: a two-step meta-analysis of individual patient data from six cohorts comprising 7897 individuals from the COnsortium of METabolomics Studies
    Nogal, Ana; Alkis, Taryn; Lee, Yura; Kifer, Domagoj; Hu, Jie; Murphy, Rachel A.; Huang, Zhe; Wang-Sattler, Rui; Kastenmüler, Gabi; Linkohr, Birgit; Barrios Barrera, Clara; Crespo Barrio, Marta; Gieger, Christian; Peters, Annette; Price, Jackie; Rexrode, Kathryn M.; Yu, Bing; Menni, Cristina (Oxford University Press, 2023)
    Aims: Myocardial infarction (MI) is a major cause of death and disability worldwide. Most metabolomics studies investigating metabolites predicting MI are limited by the participant number and/or the demographic diversity. ...
  • Redefining the role of ADAM17 in renal proximal tubular cells and its implications in an obese mouse model of pre-diabetes
    Palau González, Vanesa; Villanueva, Sofia; Jarrín, Josué; Benito, David; Márquez, Eva; Rodríguez, Eva; Soler, María José; Oliveras, Anna; Gimeno Beltran, Javier; Sans Atxer, Laia; Crespo Barrio, Marta; Pascual Santos, Julio; Barrios Barrera, Clara; Riera Oliva, Marta (MDPI, 2021)
    Acute and chronic kidney lesions induce an increase in A Disintegrin And Metalloproteinase domain 17 (ADAM17) that cleaves several transmembrane proteins related to inflammatory and fibrotic pathways. Our group has ...
  • Risk factors associated with major complications after ultrasound-guided percutaneous renal biopsy of native kidneys
    Pombas, Beatriz; Sánchez Parrila, Juan; Radosevic, Aleksandar, 1974-; Gimeno Beltran, Javier; Busto Barrera, Marcos; Barrios Barrera, Clara; Sans Atxer, Laia; Pascual Santos, Julio; Soler, María José (Karger (S. Karger AG), 2020)
    Introduction: Percutaneous renal biopsy (PRB) of native kidneys is an important tool for diagnosis and management of renal disease. In this study, we analyzed the success, safety, and risk complications of PRB in our center. ...
  • SARS-CoV-2 infection modulates ACE2 function and subsequent inflammatory responses in swabs and plasma of COVID-19 patients
    Gutiérrez-Chamorro, Lucía; Riveira Muñoz, Eva; Barrios Barrera, Clara; Palau González, Vanesa; Nevot, Maria; Pedreño-López, Sònia; Senserrich, Jordi; Massanella Luna, Marta, 1983-; Clotet, Bonaventura; Cabrera, Cecilia; Mitjà, Oriol; Crespo Barrio, Marta; Pascual Santos, Julio; Riera, Marta; Ballana Guix, Ester (MDPI, 2021)
    Angiotensin converting enzyme 2 (ACE2) is a host ectopeptidase and the receptor for the SARS-CoV-2 virus, albeit virus-ACE2 interaction goes far beyond viral entry into target cells. Controversial data exists linking viral ...
  • Should eculizumab be discontinued in patients with atypical hemolytic uremic syndrome?
    Rodriguez García, Eva; Barrios Barrera, Clara; Soler, María José (Oxford University Press, 2017)
    Atypical hemolytic uremic syndrome (aHUS) is a life-threatening disorder for which prompt diagnosis and eculizumab treatment is indicated. The time for relapse and patients at risk for relapse after eculizumab discontinuation ...

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