Browsing by Author "Barreiro Portela, Esther"

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  • Núñez, Belén; Sauleda Roig, Jaume; García Aymerich, Judith; Noguera, Aina; Monsó, Eduard; Gómez, Federico P.; Barreiro Portela, Esther; Marin, Alicia; Antó i Boqué, Josep Maria; Agustí, Alvar; Caracterización Fenotípica y Evolución de la EPOC (PAC-COPD) (Elsevier, 2016)
    INTRODUCTION: The origin of systemic inflammation in chronic obstructive pulmonary disease (COPD) patients remains to be defined, but one of the most widely accepted hypothesis is the 'spill over' of inflammatory mediators ...
  • Tang, Jun; Ramis Cabrer, Daniel, 1993-; Curull Serrano, Víctor; Wang, Xuejie; Mateu Jiménez, Mercè, 1990-; Pijuan Andujar, Lara; Duran, Xavier; Qin, Liyun; Rodríguez-Fuster, Alberto; Aguiló Espases, Rafael; Barreiro Portela, Esther (MDPI, 2020)
    Immune profile of B and T cells and tertiary lymphoid structures (TLSs) may differ in tumors of lung cancer (LC) patients with/without chronic obstructive pulmonary disease (COPD), and may also influence patient survival. ...
  • Mañas García, Laura, 1991-; Denhard, Charlotte; Mateu de Antonio, Francisco Javier; Duran Jordà, Xavier, 1974-; Gea Guiral, Joaquim; Barreiro Portela, Esther (MDPI, 2021)
    We hypothesized that the phenolic compound resveratrol mitigates muscle protein degradation and loss and improves muscle fiber cross-sectional area (CSA) in gastrocnemius of mice exposed to unloading (7dI). In gastrocnemius ...
  • Puig Vilanova, Ester, 1987- (Universitat Pompeu Fabra, 2014-07-16)
    Skeletal muscle dysfunction and wasting are major comorbidities of chronic obstructive pulmonary disease (COPD) and lung cancer (LC). Despite that the lower limb muscles are usually more severely affected, the respiratory ...
  • Wang, Xuejie; Olveira, Casilda; Girón, Rosa; García-Clemente, Marta; Máiz, Luis; Sibila, Oriol; Golpe, Rafael; Menéndez, Rosario; Rodríguez-López, Juan; Prados, Concepción; Martínez-González, Miguel A.; Rodriguez, Juan Luis; Rosa, David de la; Qin, Liyun; Duran Jordà, Xavier, 1974-; García Ojalvo, Jordi; Barreiro Portela, Esther (MDPI, 2022)
    We sought to investigate differential phenotypic characteristics according to neutrophil counts, using a biostatistics approach in a large-cohort study from the Spanish Online Bronchiectasis Registry (RIBRON). The 1034 ...
  • Pascual, Sergi, 1979- (Universitat Pompeu Fabra, 2015-11-17)
    La inflamación y el estrés oxidativo son mecanismos moleculares que contribuyen al daño y a la disfunción muscular. Existen procesos crónicos con fenómenos inflamatorios de bajo grado pero de larga duración (EPOC, con o ...
  • Roca, Josep; Vargas, Claudia; Cano, Isaac; Selivanov, Vitaly; Barreiro Portela, Esther; Maier, Dieter; Falciani, Francesco; Wagner, Peter; Cascante, Marta; García Aymerich, Judith; Kalko, Susana G.; Marin de Mas, Igor; Tegnér, Jesper; Escarrabill, Joan; Agustí, Alvar; Gomez Cabrero, David; Synergy-COPD consortium (BioMed Central, 2014)
    Background and hypothesis: Heterogeneity in clinical manifestations and disease progression in Chronic Obstructive Pulmonary Disease (COPD) lead to consequences for patient health risk assessment, stratification and ...
  • Rodríguez-García, Carlota; Barreiro Portela, Esther; Muñoz-Gall, Xavier; Bustamante, Víctor; Granda-Orive, José Ignacio de; González-Barcala, Francisco-Javier (Wiley, 2020)
    Objective: Inhalation therapy is one of the key pillars in the treatment of chronic obstructive diseases, such as asthma and COPD (Chronic obstructive pulmonary disease); however, wide number of errors occur with high ...
  • Sun, Shuangshuang; Yang, Yang; Chen, Meizi; Wang, Li; Pan, Hangcheng; Zhang, Xiuwei; Wagnieres, Georges; Mohammad, Yousser; Barreiro Portela, Esther; Pirozzolo, Giovanni; Villeneuve, P. James; Zhan, Ping; Wan, Bing; AME Lung Cancer Collaborative Group (Pioneer Bioscience Publishing Company, 2020)
    Background: Many recent studies have reported that autofluorescence bronchoscopy (AFB) has a superior sensitivity and decreased specificity in the diagnosis of bronchial cancers when compared with white-light bronchoscopy ...
  • Barreiro Portela, Esther; Wang, Xuejie; Tang, Jun (Informa Healthcare, 2019)
    Introduction: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Preclinical models of COPD have recently been developed. In those models, COPD/emphysema has been commonly ...
  • Barreiro Portela, Esther; Jiménez, Carlos; García de Pedro, Julia; Ramírez Prieto, María Teresa (Elsevier, 2020)
  • Penedo Vázquez, Antonio; Durán, Xavier; Mateu de Antonio, Francisco Javier; López Postigo, Adrián; Barreiro Portela, Esther (MDPI, 2021)
    Muscle wasting and cachexia are prominent comorbidities in cancer. Treatment with polyphenolic compounds may partly revert muscle wasting. We hypothesized that treatment with curcumin or resveratrol in cancer cachectic ...
  • Lopez-Campos, Jose Luis; Carrasco Hernández, Laura; Muñoz, Xavier; Bustamante, Víctor; Barreiro Portela, Esther (Wiley, 2018)
    The implementation of potential new step-up or step-down treatment recommendations in response to current guidelines is one of the main challenges currently faced in actual daily practice settings. In the present narrative ...
  • Sancho Muñoz, Antonio; Guitart, Maria; Rodríguez, Diego; Gea Guiral, Joaquim; Martínez-Llorens, Juana Mª; Barreiro Portela, Esther (Wiley, 2021)
    Sarcopenia is a major comorbidity in chronic obstructive pulmonary (COPD). Whether deficient muscle repair mechanisms and regeneration exist in the vastus lateralis (VL) of sarcopenic COPD remains debatable. In the VL of ...
  • Leisman, Daniel E.; Barreiro Portela, Esther; Maslove, David M.; Prediction models aim to use available data to predict a health state or outcome that has not yet been observed. Prediction is primarily relevant to clinical practice, but is also used in research, and administration. While prediction modeling involves estimating the relationship between patient factors and outcomes, it is distinct from casual inference. Prediction modeling thus requires unique considerations for development, validation, and updating. This document represents an effort from editors at 31 respiratory, sleep, and critical care medicine journals to consolidate contemporary best practices and recommendations related to prediction study design, conduct, and reporting. Herein, we address issues commonly encountered in submissions to our various journals. Key topics include considerations for selecting predictor variables, operationalizing variables, dealing with missing data, the importance of appropriate validation, model performance measures and their interpretation, and good reporting practices. Supplemental discussion covers emerging topics such as model fairness, competing risks, pitfalls of "modifiable risk factors", measurement error, and risk for bias. This guidance is not meant to be overly prescriptive; we acknowledge that every study is different, and no set of rules will fit all cases. Additional best practices can be found in the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) guidelines, to which we refer readers for further details. (Wolters Kluwer (LWW), 2020)
  • Greising, Sarah M.; Ottenheijm, Coen A.C.; O’Halloran, Ken D.; Barreiro Portela, Esther (American Physiological Society, 2018)
    The diaphragm is the main inspiratory muscle and is required to be highly active throughout the life span. The diaphragm muscle must be able to produce and sustain various behaviors that range from ventilatory to nonventilatory ...
  • Barreiro Portela, Esther; Sancho Muñoz, Antonio; Puig Vilanova, Ester, 1987-; Salazar Degracia, Anna; Pascual Guàrdia, Sergi, 1979-; Casadevall Fusté, Carme; Gea Guiral, Joaquim (American Physiological Society, 2019)
    Quadriceps muscle weakness and wasting are common comorbidities in chronic obstructive pulmonary disease (COPD). Micro-RNA expression upregulation may favor muscle mass growth and differentiation. We hypothesized that the ...
  • Wang, Xuejie; Villa, Carmen; Dobarganes, Yadira; Olveira, Casilda; Girón, Rosa; García-Clemente, Marta; Máiz, Luis; Sibila, Oriol; Golpe, Rafael; Menéndez, Rosario; Rodríguez-López, Juan; Prados, Concepción; Martínez-García, Miguel Ángel; Rodriguez, Juan Luis; Rosa, David de la; Duran, Xavier; Barreiro Portela, Esther (MDPI, 2021)
    We hypothesized that systemic inflammatory and nutritional parameters may differ between male and female patients with non-CF bronchiectasis. In a large patient cohort from the Spanish Online Bronchiectasis Registry (RIBRON), ...
  • Busquets, Silvia; Pérez-Peiró, Maria; Salazar Degracia, Anna; Argilés, Josep M.; Serpe, Roberto; Rojano-Toimil, Alba; López Soriano, Francisco J.; Barreiro Portela, Esther (Wiley, 2020)
    Muscle wasting is associated with chronic diseases and cancer. Elucidation of the biological mechanism involved in the process of muscle mass loss and cachexia may help identify therapeutic targets. We hypothesized that ...
  • Mañas García, Laura, 1991- (2021-03-02)
    La atrofia muscular por desuso en el contexto de las enfermedades crónicas, como enfermedades respiratorias, cáncer o un reposo prolongado, se caracteriza por la pérdida de masa y función muscular. Además, el desgaste ...