Browsing by Author "Barberà, Joan Albert"

Sort by: Order: Results:

  • Atrophy signaling pathways in respiratory and limb muscles of guinea pigs exposed to chronic cigarette smoke: role of soluble guanylate cyclase stimulation
    Peinado, Victor I.; Guitart, Maria; Blanco, Isabel; Tura-Ceide, Olga; Paul, Tanja; Barberà, Joan Albert; Barreiro Portela, Esther (American Physiological Society, 2023)
    Skeletal muscle dysfunction in chronic obstructive pulmonary disease (COPD) is characterized by a significant reduction in muscle strength and endurance. Preclinical studies show that stimulation of the soluble guanylate ...
  • Characterisation and prognosis of undiagnosed chronic obstructive pulmonary disease patients at their first hospitalisation
    Balcells Vilarnau, Eva, 1967-; Gimeno Santos, Elena, 1980-; De Batlle, Jordi; Ramon, Maria Antonia; Rodríguez, Esther; Benet, Marta; Ferrer, Jaume; Farrero, Eva; Ferrer, Antoni-Lluc, 1942-; Guerra, Stefano; Ferrer, Jaume; Sauleda Roig, Jaume; Barberà, Joan Albert; Agustí, Alvar; Rodriguez, Robert, 1968-; Gea Guiral, Joaquim; Antó i Boqué, Josep Maria; García Aymerich, Judith (BioMed Central, 2015)
    Background. Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD./nMethods. The PAC-COPD cohort included 342 COPD ...
  • Chromosomal bands affected by acute oil exposure and DNA repair errors
    Monyarch, Gemma; De Castro Reis, Fernanda; Zock, Jan-Paul; Giraldo, Jesús; Pozo Rodríguez, Francisco; Espinosa Díaz, Ana; Rodríguez Trigo, Gema; Gómez, Federico P.; Antó i Boqué, Josep Maria; Coll, Maria; Barberà, Joan Albert; Fuster, Carme (Public Library of Science (PLoS), 2013)
    Background: In a previous study, we showed that individuals who had participated in oil clean-up tasks after the wreckage of the Prestige presented an increase of structural chromosomal alterations two years after the acute ...
  • Circulating cell biomarkers in pulmonary arterial hypertension: relationship with clinical heterogeneity and therapeutic response
    Tura-Ceide, Olga; Blanco, Isabel; Garcia-Lucio, Jéssica; del Pozo, Roberto; García, Agustín Roberto; Ferrer, Elisabet; Crespo, Isabel; Rodríguez Chiaradia, Diego Agustín; Simeon-Aznar, Carmen Pilar; López-Meseguer, Manuel; Martín-Ontiyuelo, Clara; Peinado, Victor I.; Barberà, Joan Albert (MDPI, 2021)
    Background: Endothelial dysfunction is central to PAH. In this study, we simultaneously analysed circulating levels of endothelial microvesicles (EMVs) and progenitor cells (PCs) in PAH and in controls, as biomarkers of ...
  • Follow-Up Genotoxic Study: Chromosome Damage Two and Six Years after Exposure to the Prestige Oil Spill.
    Hildur, Kristin; Templado, Cristina; Zock, Jan-Paul; Giraldo, Jesús; Pozo Rodríguez, Francisco; Frances, Alexandra; Monyarch, Gemma; Rodríguez Trigo, Gema; Rodriguez-Rodriguez, Emma; Souto, Ana; Gómez, Federico P.; Antó i Boqué, Josep Maria; Barberà, Joan Albert; Fuster, Carme (Public Library of Science, 2015)
    BACKGROUND: The north-west coast of Spain was heavily contaminated by the Prestige oil spill, in 2002. Individuals who participated in the clean-up tasks showed increased chromosome damage two years after exposure. Long-term ...
  • Inspiratory capacity-to-total lung capacity ratio and dyspnoea predict exercise capacity decline in COPD
    Ramon, Maria Antonia; Ferrer, Jaume; Gimeno Santos, Elena, 1980-; Donaire González, David; Rodríguez, Esther; Balcells Vilarnau, Eva, 1967-; De Batlle, Jordi; Benet, Marta; Guerra, Stefano; Sauleda Roig, Jaume; Ferrer, Antoni-Lluc, 1942-; Farrero, Eva; Gea Guiral, Joaquim; Barberà, Joan Albert; Agustí, Alvar; Rodríguez Roisin, Robert; Antó i Boqué, Josep Maria; García Aymerich, Judith; PAC-COPD Study Group (Wiley, 2016)
    BACKGROUND AND OBJECTIVE: Exercise capacity decline is a predictor of mortality in patients with chronic obstructive pulmonary disease (COPD). Static pulmonary hyperinflation is a key determinant of exercise performance, ...
  • Management and outcomes in chronic thromboembolic pulmonary hypertension: From expert centers to a nationwide perspective.
    Escribano-Subías, Pilar; del Pozo, Roberto; Román-Broto, Antonio; Domingo Morera, Juan Antonio; Lara-Padrón, Antonio; Elías Hernández, Teresa; Molina Ferragut, Luis; Blanco, Isabel; Cortina, Jose; Barberà, Joan Albert; REHAP Investigators (Elsevier, 2016)
    BACKGROUND: The Spanish "Registry of Pulmonary Arterial Hypertension" (REHAP), started in 2007, includes chronic thromboembolic hypertension (CTEPH) patients. Based on data provided by this registry and retrospective data ...
  • Persistence of Breakage in Specific Chromosome Bands 6 Years after Acute Exposure to Oil.
    Frances, Alexandra; Hildur, Kristin; Barberà, Joan Albert; Rodríguez Trigo, Gema; Zock, Jan-Paul; Giraldo, Jesús; Monyarch, Gemma; Rodriguez-Rodriguez, Emma; De Castro Reis, Fernanda; Souto, Ana; Gómez, Federico P.; Pozo Rodríguez, Francisco; Templado, Cristina; Fuster, Carme (Public Library of Science (PLoS) , 2016)
    BACKGROUND: The identification of breakpoints involved in chromosomal damage could help to detect genes involved in genetic disorders, most notably cancer. Until now, only one published study, carried out by our group, has ...
  • Soluble guanylate cyclase stimulation reduces oxidative stress in experimental Chronic Obstructive Pulmonary Disease
    Paul, Tanja; Salazar Degracia, Anna; Peinado, Victor I.; Tura-Ceide, Olga; Blanco, Isabel; Barreiro Portela, Esther; Barberà, Joan Albert (Public Library of Science (PLoS), 2018)
    OBJECTIVE: Soluble guanylate cyclase (sGC) is a key enzyme of the nitric oxide-cyclic guanosine 3',5'-monophosphate (NO-cGMP) signaling pathway, and its pharmacological stimulation has been shown to prevent the development ...