Browsing by Author "Bachs Valldeneu, Oriol"

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  • p27
    Pippa, Raffaella; Espinosa Blay, Lluís; Gundem, Gunes; Garcia Escudero, Ramon; Dominguez, Ana; Orlando, Serena; Gallastegui, E.; Saiz, Cristina; Besson, Arnaud; Pujol, Maria Jesus; López Bigas, Núria; Paramio, Jesus M.; Bigas Salvans, Anna; Bachs Valldeneu, Oriol (Universitat Pompeu Fabra, 2011-12)
    The cyclin-cdk (cyclin-dependent kinase) inhibitor p27(Kip1) (p27) has a crucial negative role on cell cycle progression. In addition to its classical role as a cyclin-cdk inhibitor, it also performs cyclin-cdk-independent ...
  • p27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes
    Perearnau, Anna; Orlando, Serena; Islam, Abul, 1978-; Gallastegui Calvache, Edurne; Martínez, Jonatan; Jordan Vallès, Albert; Bigas Salvans, Anna; Aligué, Rosa; Pujol, Maria Jesús; Bachs Valldeneu, Oriol (Oxford University Press, 2017)
    The cyclin-dependent kinase inhibitor p27Kip1 (p27) also behaves as a transcriptional repressor. Data showing that the p300/CBP-associated factor (PCAF) acetylates p27 inducing its degradation suggested that PCAF and p27 ...
  • Role of p27Kip1 as a transcriptional regulator
    Bachs Valldeneu, Oriol; Gallastegui Calvache, Edurne; Orlando, Serena; Bigas Salvans, Anna; Morante-Redolat, José Manuel; Serratosa, Joan; Fariñas, Isabel; Aligué, Rosa; Pujol, Maria Jesús (Impact Journal, 2018)
    The protein p27Kip1 is a member of the Cip/Kip family of cyclin-dependent kinase (Cdk) inhibitors. It interacts with both the catalytic and the regulatory subunit (cyclin) and introduces a region into the catalytic cleave ...

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