Browsing by Author "Avillach, Paul"

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  • Automatic filtering and substantiation of drug safety signals
    Bauer-Mehren, Anna; van Mulligen, Erik M.; Avillach, Paul; Carrascosa Baena, María Carmen, 1972-; García Serna, Ricard; Piñero González, Janet, 1977-; Singh, Barat; Lopes, Pedro; Oliveira, José Luis; Diallo, Gayo; Ahlberg Helgee, Ernst; Boyer, Scott; Mestres i López, Jordi; Sanz, Ferran; Kors, Jan A.; Furlong, Laura I., 1971- (Public Library of Science (PLoS), 2012)
    Drug safety issues pose serious health threats to the population and constitute a major cause of mortality worldwide. Due to the prominent implications to both public health and the pharmaceutical industry, it is of great ...
  • Dementia prevalence and incidence in a federation of European Electronic Health Record databases: The European Medical Informatics Framework resource
    Perera, Gayan; Pedersen, Lars; Ansel, David; Alexander, Myriam; Arrighi, H. Michael; Avillach, Paul; Foskett, Nadia; Gini, Rosa; Gordon, Mark F.; Gungabissoona, Usha; Mayer, Miguel Ángel, 1960-; Novak, Gerald; Rijnbeek, Peter; Trifirò, Gianluca; van der Lei, Johan; Visser, Pieter Jelle; Stewart, Robert (Elsevier, 2018)
    INTRODUCTION: The European Medical Information Framework consortium has assembled electronic health record (EHR) databases for dementia research. We calculated dementia prevalence and incidence in 25 million persons from ...
  • Gathering and exploring scientific knowledge in pharmacovigilance
    Lopes, Pedro; Nunes, Tiago; Campos, David; Furlong, Laura I., 1971-; Bauer-Mehren, Anna; Sanz, Ferran; Carrascosa Baena, María Carmen, 1972-; Mestres i López, Jordi; Kors, Jan A.; Singh, Barat; van Mulligen, Erik M.; van der Lei, Johan; Diallo, Gayo; Avillach, Paul; Ahlberg Helgee, Ernst; Boyer, Scott; Díaz, Carlos; Oliveira, José Luis (Public Library of Science (PLoS), 2013)
    Pharmacovigilance plays a key role in the healthcare domain through the assessment, monitoring and discovery of interactions amongst drugs and their effects in the human organism. However, technological advances in this ...
  • Rcupcake: an R package for querying and analyzing biomedical data through the BD2K PIC-SURE RESTful API
    Gutiérrez Sacristán, Alba; Guedj, Romain; Korodi, Gabor; Stedman, Jason; Furlong, Laura I., 1971-; Patel, Chirag J.; Kohane, Isaac S.; Avillach, Paul (Oxford University Press, 2018)
    MOTIVATION: In the era of big data and precision medicine, the number of databases containing clinical, environmental, self-reported and biochemical variables is increasing exponentially. Enabling the experts to focus on ...
  • The EU-ADR Web Platform: delivering advanced pharmacovigilance tools
    Oliveira, José Luis; Lopes, Pedro; Nunes, Tiago; Campos, David; Boyer, Scott; Ahlberg Helgee, Ernst; van Mulligen, Erik M.; Kors, Jan A.; Singh, Barat; Furlong, Laura I., 1971-; Sanz, Ferran; Bauer-Mehren, Anna; Carrascosa Baena, María Carmen, 1972-; Mestres i López, Jordi; Avillach, Paul; Diallo, Gayo; Díaz, Carlos; van der Lei, Johan (John Wiley & Sons, 2013)
    PURPOSE: Pharmacovigilance methods have advanced greatly during the last decades, making post-market drug assessment an essential drug evaluation component. These methods mainly rely on the use of spontaneous reporting ...
  • Vascular and metabolic risk factor differences prior to dementia diagnosis: a multidatabase case-control study using European electronic health records
    Perera, Gayan; Rijnbeek, Peter; Alexander, Myriam; Ansel, David; Avillach, Paul; Duarte Salles, Talita, 1985-; Gordon, Mark F.; Lapi, Francesco; Mayer, Miguel Ángel, 1960-; Pasqua, Alessandro; Pedersen, Lars; van der Lei, Johan; Visser, Pieter Jelle; Stewart, Robert (BMJ Publishing Group, 2020)
    Objective: The objective of the study is to compare body mass index (BMI), systolic/diastolic blood pressure (SBP/DBP) and serum total cholesterol levels between dementia cases and controls at multiple time intervals prior ...

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