Browsing by Author "Aterido Ballonga, Adrià, 1990-"

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  • A combined transcriptomic and genomic analysis identifies a gene signature associated with the response to anti-TNF therapy in rheumatoid arthritis
    Aterido Ballonga, Adrià, 1990-; Cañete Crespillo, Juan de Dios; Tornero, Jesús; Blanco, Francisco; Fernández-Gutiérrez, Benjamín; Pérez-García, Carolina; Alperiz, Mercedes; Olivé, Alex; Corominas, Héctor; Martínez-Taboada, Víctor; González-Alvaro, Isidoro; Fernández-Nebro, Antonio; Erra, Alba; López Lasanta, María; López Corbeto, Mireia; Palau, Núria; Marsal, Sara; Julià, Antonio (Frontiers, 2019)
    Background: Rheumatoid arthritis (RA) is the most frequent autoimmune disease involving the joints. Although anti-TNF therapies have proven effective in the management of RA, approximately one third of patients do not show ...
  • Functional rare variants influence the clinical response to anti-TNF therapy in Crohn's disease
    Chaparro Domínguez, María Ángeles; Aterido Ballonga, Adrià, 1990-; Gisbert, Javier P. (SAGE Publications, 2019)
    Background: The effect of low-frequency functional variation on anti-tumor necrosis factor alpha (TNF) response in Crohn's disease (CD) patients remains unexplored. The objective of this study was to investigate the impact ...
  • Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis
    Aterido Ballonga, Adrià, 1990-; Pérez-García, Carolina; Julià, Antonio (BMJ Publishing Group, 2019)
    OBJECTIVE: Psoriatic arthritis (PsA) is a chronic inflammatory arthritis affecting up to 30% of patients with psoriasis (Ps). To date, most of the known risk loci for PsA are shared with Ps, and identifying disease-specific ...
  • Genome-wide pathway analysis identifies genetic pathways associated with psoriasis
    Aterido Ballonga, Adrià, 1990-; Julià, Antonio; Ferrándiz, Carlos; Puig, Lluís; Fonseca, Eduardo; Fernández-López, Emilia; Dauden, Esteban; Sánchez-Carazo, José Luís; López-Estebaranz, José Luís; Moreno-Ramírez, David; Vanaclocha, Francisco; Herrera, Enrique; Cueva, Pablo de la; Dand, Nick; Palau, Núria; Alonso, Arnald; López-Lasanta, María; Tortosa, Raül; García-Montero, Andrés; Codó, Laia; Gelpí, Josep Lluís; Bertranpetit, Jaume, 1952-; Absher, Devin; Capon, Francesca; Myers, Richard M.; Barker, Jonathan N.; Marsal, Sara (Elsevier, 2016)
    Psoriasis is a chronic inflammatory disease with a complex genetic architecture. To date, the psoriasis heritability is only partially explained. However, there is increasing evidence that the missing heritability in ...
  • Genome-wide pathway analysis identifies VEGF pathway association with oral ulceration in systemic lupus erythematosus
    Aterido Ballonga, Adrià, 1990-; Julià Cano, Antoni; Marsal Barril, Sara (BioMed Central, 2017)
    Systemic lupus erythematosus (SLE) is a genetically complex rheumatic disease characterized by heterogeneous clinical manifestations of unknown etiology. Recent studies have suggested the existence of a genetic basis for ...
  • Variation at FCGR2A and Functionally Related Genes Is Associated with the Response to Anti-TNF Therapy in Rheumatoid Arthritis
    Avila Pedretti, Gabriela; Tornero, Jesús; Fernández-Nebro, Antonio; Blanco, Francisco; González-Alvaro, Isidoro; Cañete Crespillo, Juan de Dios; Maymó Guarch, Joan; Alperiz, Mercedes; Fernández-Gutiérrez, Benjamín; Olivé, Alex; Corominas, Héctor; Erra, Alba; Aterido Ballonga, Adrià, 1990-; López Lasanta, María; Tortosa, Raül; Julià, Antonio; Marsal, Sara (Public Library of Science, 2015)
    OBJECTIVE: Anti-TNF therapies have been highly efficacious in the management of rheumatoid arthritis (RA), but 25-30% of patients do not show a significant clinical response. There is increasing evidence that genetic ...

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