Browsing by Author "Arnan Ros, Carme"

Sort by: Order: Results:

  • A Point Mutation in a lincRNA Upstream of GDNF Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies
    Plassais, Jocelyn; Lagoutte, Laetitia; Correard, Solenne; Paradis, Manon; Guaguère, Eric; Hédan, Benoit; Pommier, Alix; Botherel, Nadine; Cadiergues, Marie-Christine; Pilorge, Philippe; Silversides, David; Bizot, Maud; Amuels, Mark; Arnan Ros, Carme; Johnson, Rory; Hitte, Christophe; Salbert, Gilles; Méreau, Agnès; Quignon, Pascale; Derrien, Thomas; André, Catherine (Public Library of Science (PLoS), 2016)
    Human Hereditary Sensory Autonomic Neuropathies (HSANs) are characterized by insensitivity to pain, sometimes combined with self-mutilation. Strikingly, several sporting dog breeds are particularly affected by such ...
  • bsAS, an antisense long non-coding RNA, essential for correct wing development through regulation of blistered/DSRF isoform usage
    Pérez-Lluch, Sílvia; Klein, Cecilia C.; Breschi, Alessandra, 1988-; Ruiz-Romero, Marina; Abad, Amaya; Palumbo, Emilio; Bekish, Lyazzat; Arnan Ros, Carme; Guigó Serra, Roderic (Public Library of Science (PLoS), 2020)
    Natural Antisense Transcripts (NATs) are long non-coding RNAs (lncRNAs) that overlap coding genes in the opposite strand. NATs roles have been related to gene regulation through different mechanisms, including post-transcriptional ...
  • CapTrap-seq: a platform-agnostic and quantitative approach for high-fidelity full-length RNA sequencing
    Carbonell Sala, Silvia; Perteghella, Tamara; Lagarde, Julien; Nishiyori, Hiromi; Palumbo, Emilio; Arnan Ros, Carme; Takahashi, Hazuki; Carninci, Piero; Uszczynska-Ratajczak, Barbara; Guigó Serra, Roderic (Nature Research, 2024)
    Long-read RNA sequencing is essential to produce accurate and exhaustive annotation of eukaryotic genomes. Despite advancements in throughput and accuracy, achieving reliable end-to-end identification of RNA transcripts ...
  • CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis
    Ounzain, Samir; Micheletti, Rudi; Arnan Ros, Carme; Plaisance, Isabelle; Cecchi, Dario; Schroen, Blanche; Reverter, Ferran; Alexanian, Michael; Gonzales, Christine; Ng, Shi Yan; Bussotti, Giovanni, 1983-; Pezzuto, Iole; Notredame, Cedric; Heymans, Stephane; Guigó Serra, Roderic; Johnson, Rory; Pedrazzini, Thierry (Elsevier, 2015)
    Long noncoding RNAs (lncRNAs) are emerging as important regulators of developmental pathways. However, their roles in human cardiac precursor cell (CPC) remain unexplored. To characterize the long noncoding transcriptome ...
  • DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAs
    Aparicio i Prat, Estel, 1986-; Arnan Ros, Carme; Sala, Ilaria; Bosch Roca, Núria; Guigó Serra, Roderic; Johnson, Rory (BioMed Central, 2015)
    Background. CRISPR genome-editing technology makes it possible to quickly and cheaply delete non-protein-coding regulatory elements. We present a vector system adapted for this purpose called DECKO (Double Excision CRISPR ...
  • Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization.
    Mariotti, Marco, 1984-; Santesmasses Ruiz, Didac, 1978-; Capella Gutiérrez, Salvador Jesús, 1985-; Mateo, Andrea; Arnan Ros, Carme; Johnson, Rory; D’Aniello, Salvatore; Yim, Sun Hee; Gladyshev, Vadim N.; Serras Rigalt, Florenci; Corominas Guiu, Montserrat; Gabaldón Estevan, Juan Antonio, 1973-; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press, 2015)
    Selenoproteins are proteins that incorporate selenocysteine (Sec), a nonstandard amino acid encoded by UGA, normally a stop codon. Sec synthesis requires the enzyme Selenophosphate synthetase (SPS or SelD), conserved in ...
  • GENCODE: reference annotation for the human and mouse genomes in 2023
    Frankish, Adam; Carbonell Sala, Silvia; Arnan Ros, Carme; Calvet, Ferriol; Lagarde, Julien; Guigó Serra, Roderic; Flicek, Paul (Oxford University Press, 2023)
    GENCODE produces high quality gene and transcript annotation for the human and mouse genomes. All GENCODE annotation is supported by experimental data and serves as a reference for genome biology and clinical genomics. The ...
  • MapToCleave: High-throughput profiling of microRNA biogenesis in living cells
    Kang, Wenjing; Fromm, Bastian; Houben, Anna J.; Høye, Eirik; Bezdan, Daniela; Arnan Ros, Carme; Thrane, Kim; Asp, Michaela; Johnson, Rory; Biryukova, Inna; Friedländer, Marc R. (Elsevier, 2021)
    Previous large-scale studies have uncovered many features that determine the processing of microRNA (miRNA) precursors; however, they have been conducted in vitro. Here, we introduce MapToCleave, a method to simultaneously ...
  • Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages
    Arnan Ros, Carme; Ullrich, Sebastian, 1984-; Pulido-Quetglas, Carlos; Nurtdinov, Ramil; Esteban, Alexandre; Blanco-Fernandez, Joan; Aparicio-Prat, Estel; Johnson, Rory; Pérez-Lluch, Sílvia; Guigó Serra, Roderic (BioMed Central, 2022)
    CRISPR-Cas9 screening libraries have arisen as a powerful tool to identify protein-coding (pc) and non-coding genes playing a role along different processes. In particular, the usage of a nuclease active Cas9 coupled to a ...
  • Scalable Design of Paired CRISPR Guide RNAs for Genomic Deletion
    Pulido-Quetglas, Carlos; Aparicio i Prat, Estel, 1986-; Arnan Ros, Carme; Polidori, Taisia; Hermoso Pulido, Antonio; Palumbo, Emilio; Ponomarenko, Julia; Guigó Serra, Roderic; Johnson, Rory (Public Library of Science (PLoS), 2017)
    CRISPR-Cas9 technology can be used to engineer precise genomic deletions with pairs of single guide RNAs (sgRNAs). This approach has been widely adopted for diverse applications, from disease modelling of individual loci, ...

Search DSpace

Browse

My Account

In collaboration with Compliant to Partaking