Visualitza per autoria "Arambilet, David"

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  • Enhanced hemato-endothelial specification during human embryonic differentiation through developmental cooperation between AF4-MLL and MLL-AF4 fusions
    Bueno, Clara; Calero-Nieto, Fernando J.; Wang, Xiaonan; Valdés-Mas, Rafael; Gutiérrez-Agüera, Francisco; Roca-Ho, Heleia; Ayllon, Verónica; Real, Pedro J.; Arambilet, David; Espinosa Blay, Lluís; Torres-Ruiz, Raul; Agraz-Doblas, Antonio; Varela, Ignacio; de Boer, Jasper; Bigas Salvans, Anna; Gottgens, Bertie; Marschalek, Rolf; Menéndez, Pablo (Ferrata Storti Foundation, 2019)
    The t(4;11)(q21;q23) translocation is associated with high-risk infant pro-B-cell acute lymphoblastic leukemia and arises prenatally during embryonic/fetal hematopoiesis. The developmental/pathogenic contribution of the ...
  • β-Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T-cell acute lymphoblastic leukemia
    García Hernández, Violeta; Arambilet, David; Guillén, Yolanda; Lobo-Jarne, Teresa; Maqueda, Maria; Gekas, Christos; González, Jessica; Iglesias, Arnau; Vega García, Nerea; Sentís Carreras, Inés 1990-; Trincado Alonso, Juan Luis, 1987-; Márquez-López, Ian; Heyn, Holger; Camós, Mireia; Espinosa Blay, Lluís; Bigas Salvans, Anna (Wiley, 2023)
    Understanding the molecular mechanisms that contribute to the appearance of chemotherapy resistant cell populations is necessary to improve cancer treatment. We have now investigated the role of β-catenin/CTNNB1 in the ...

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