Browsing by Author "Aloia, Luigi"

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  • Aloia, Luigi; Gutiérrez, Arantxa; Martín Caballero, Juan; Di Croce, Luciano (Wiley-Blackwell, 2015)
    Id proteins are dominant-negative regulators within the HLH family of proteins. In embryonic stem cells (ESCs), Id1 and Id3 maintain the pluripotent state by preventing neural differentiation. The Id1-interacting protein ...
  • Morey Ramonell, Lluís; Santanach Buxaderas, Alexandra, 1988-; Blanco, Enrique; Aloia, Luigi; Nora, Elphège P.; Bruneau, Benoit G.; Di Croce, Luciano (Elsevier, 2015)
    Polycomb complexes (PRC1 and PRC2) are essential regulators of epigenetic gene silencing in embryonic and adult stem cells. Emerging evidence suggests that the core subunit composition regulates distinct biological processes, ...
  • Morey Ramonell, Lluís; Aloia, Luigi; Cozzuto, Luca; Aznar Benitah, Salvador; Di Croce, Luciano (Elsevier, 2013)
    The Polycomb repressive complex 1 (PRC1) is required for decisions of stem cell fate. In mouse embryonic stem cells (ESCs), two major variations of PRC1 complex, defined by the mutually exclusive presence of Cbx7 or RYBP, ...
  • Aloia, Luigi; Di Stefano, Bruno, 1984-; Sessa, Alessandro; Morey, Lluis; Santanach, Alexandra; Gutierrez, Arantxa; Cozzuto, Luca; Aznar Benitah, Salvador; Graf, T. (Thomas); Broccoli, Vania; Di Croce, Luciano (Cold Spring Harbor Laboratory Press (CSHL Press), 2014)
    The molecular mechanisms underlying specification from embryonic stem cells (ESCs) and maintenance of neural progenitor cells (NPCs) are largely unknown. Recently, we reported that the Zuotin-related factor 1 (Zrf1) is ...
  • Aloia, Luigi; Demajo Meseguer, Santiago, 1985-; Di Croce, Luciano (Taylor & Francis (Routledge), 2015)
    The Zuotin-related factor 1, ZRF1, has recently been identified as an epigenetic regulator of gene transcription in stem cells and cancer. During differentiation of human teratocarcinoma cells, ZRF1 promotes transcriptional ...

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