Browsing by Author "Alexopoulos, Leonidas G."

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  • Kotelnikova, Ekaterina; Kiani, Narsis A.; Abad Adan, Elena; Martínez Lapiscina, Elena H.; Andorrà, Magí; Zubizarreta, Irati; Pulido Valdeolivas, Irene; Pertsovskaya, Inna; Alexopoulos, Leonidas G.; Olsson, Tomas; Martin, Roland; Paul, Friedemann; Tegnér, Jesper; García Ojalvo, Jordi; Villoslada, Pablo (Public Library of Science (PLoS), 2017)
    Multiple Sclerosis (MS) is an autoimmune disease driving inflammatory and degenerative processes that damage the central nervous system (CNS). However, it is not well understood how these events interact and evolve to evoke ...
  • Bermúdez-Lekerika, Paola; Crump, Katherine B.; Tseranidou, Sofia; Nüesch, Andrea; Kanelis, Exarchos; Alminnawi, Ahmad; Baumgartner, Laura; Muñoz-Moya, Estefano; Compte, Roger; Gualdi, Francesco; Alexopoulos, Leonidas G.; Geris, Liesbet; Wuertz-Kozak, Karin; Le Maitre, Christine L.; Noailly, Jérôme; Gantenbein, Benjamin (Frontiers, 2022)
    Low back pain is a highly prevalent, chronic, and costly medical condition predominantly triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and biochemical changes in intervertebral discs ...
  • Baumgartner, Laura; Wuertz-Kozak, Karin; Le Maitre, Christine L.; Wignall, Francis; Richardson, Stephen M.; Hoyland, Judith; Ruiz Wills, Carlos; González Ballester, Miguel Ángel, 1973-; Neidlin, Michael; Alexopoulos, Leonidas G.; Noailly, Jérôme (MDPI, 2021)
    Intervertebral disc (IVD) degeneration is a major risk factor of low back pain. It is defined by a progressive loss of the IVD structure and functionality, leading to severe impairments with restricted treatment options ...
  • Segarra-Queralt, Maria; Neidlin, Michael; Tió, Laura; Monfort, Jordi; Monllau García, Juan Carlos; González Ballester, Miguel Ángel, 1973-; Alexopoulos, Leonidas G.; Piella Fenoy, Gemma; Noailly, Jérôme (Nature Research, 2022)
    In osteoarthritis (OA), chondrocyte metabolism dysregulation increases relative catabolic activity, which leads to cartilage degradation. To enable the semiquantitative interpretation of the intricate mechanisms of OA ...

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