Browsing by Author "Aguilar, Ruth"

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  • Ambient air pollution in relation to SARS-CoV-2 infection, antibody response, and COVID-19 disease: a Cohort study in Catalonia, Spain (COVICAT Study)
    Kogevinas, Manolis; Castaño Vinyals, Gemma; Karachaliou, Marianna; Espinosa Díaz, Ana; García Aymerich, Judith; Jiménez, Alfons; Vidal, Marta; O’Callaghan-Gordo, Cristina; Cirach, Marta; Santano, Rebeca; Barrios, Diana; Puyol, Laura; Rubio, Rocío; Izquierdo, Luis; Nieuwenhuijsen, Mark J.; Dadvand, Payam; Aguilar, Ruth; Moncunill, Gemma; Dobaño, Carlota; Tonne, Cathryn (National Institute of Environmental Health Sciences (NIEHS), 2021)
    Background: emerging evidence links ambient air pollution with coronavirus 2019 (COVID-19) disease, an association that is methodologically challenging to investigate. Objectives: we examined the association between long-term ...
  • Antibody responses to common viruses according to COVID-19 severity and postacute sequelae of COVID-19
    Karachaliou, Marianna; Ranzani, Otavio; Espinosa Díaz, Ana; Iraola Guzmán, Susana; Castaño Vinyals, Gemma; Vidal, Marta; Jiménez, Alfons; Bañuls, Marc; Alonso Nogués, Eva; Aguilar, Ruth; García Aymerich, Judith; Cid Ibeas, Rafael de; Dobaño, Carlota; Moncunill, Gemma; Kogevinas, Manolis (Wiley, 2024)
    Limited research suggests that certain viruses reactivate in severe-acute-respiratory-syndrome-coronavirus 2 infection, contributing to the development of postacute sequelae of COVID-19 (PASC). We examined 1083 infected ...
  • Assessment of the Combined Effect of Epstein-Barr Virus and Plasmodium falciparumInfections on Endemic Burkitt Lymphoma Using a Multiplex Serological Approach
    Aguilar, Ruth; Casabonne, Delphine; O’Callaghan-Gordo, Cristina; Vidal, Marta; Campo, Joseph J.; Mutalima, Nora; Angov, Evelina; Dutta, Sheetij; Gaur, Deepak; Chitnis, Chetan E.; Chauhan, Virander; Michel, Angelika; de Sanjosé, Silvia; Waterboer, Tim; Kogevinas, Manolis; Newton, Rob; Dobaño, Carlota (Frontiers, 2017)
    Epstein-Barr virus (EBV) is a necessary cause of endemic Burkitt lymphoma (eBL), while the role of Plasmodium falciparum in eBL remains uncertain. This study aimed to generate new hypotheses on the interplay between both ...
  • Determinants of early antibody responses to COVID-19 mRNA vaccines in a cohort of exposed and naïve healthcare workers
    Moncunill, Gemma; Aguilar, Ruth; Ribes, Marta; Ortega, Natalia; Rubio, Rocío; Molina, María José; Vidal, Marta; Barrios, Diana; Mitchell, Robert A.; Jiménez, Alfons; Castellana, Cristina; Rodó, Pau; Méndez, Susana; Llupià, Anna; Puyol, Laura; Rodrigo Melero, Natalia; Carolis, Carlo; Mayor, Alfredo; Izquierdo, Luis; Trilla, Antoni; Vilella, Anna; García-Basteiro, Alberto L.; Dobaño, Carlota (Elsevier, 2022)
    Background: Two doses of mRNA vaccination have shown >94% efficacy at preventing COVID-19 mostly in naïve adults, but it is not clear if the second dose is needed to maximize effectiveness in those previously exposed to ...
  • Disruption of cellular immune response among male rotating night shift workers in Spain- The HORMONIT study
    Harding, Barbara N.; Aguilar, Ruth; Espinosa Díaz, Ana; Castaño Vinyals, Gemma; Papantoniou, Kyriaki, 1983-; Navarrete, José María; Such Faro, Patricia; Torrejón, Antonio; Dobaño, Carlota; Moncunill, Gemma; Kogevinas, Manolis (Frontiers, 2022)
    Introduction: Preliminary studies suggest that night shift work is associated with a desynchronization of rhythmic immune markers, possibly explaining the increased risk of infection, cardiometabolic disorders, and cancer ...
  • High-resolution kinetics and cellular determinants of SARS-CoV-2 antibody response over two years after COVID-19 vaccination
    Rubio, Rocío; Macià, Dídac; Barrios, Diana; Vidal, Marta; Jiménez, Alfons; Molinos-Albert, Luis M.; Díaz, Natalia; Canyelles, Mar; Lara Escandell, Maria; Planchais, Cyril; Santamaria, Pere; Carolis, Carlo; Izquierdo, Luis; Aguilar, Ruth; Moncunill, Gemma; Dobaño, Carlota (Elsevier, 2024)
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) studies usually rely on cross-sectional data of large cohorts but limited repeated samples, overlooking significant inter-individual antibody kinetic differences. ...
  • Individual blood concentrations of persistent organic pollutants and chemical elements, and COVID-19: A prospective cohort study in Barcelona
    Porta Serra, Miquel; Pumarega Rodríguez, José Antonio; Gasull Panadès, Magda; Aguilar, Ruth; Henríquez Hernández, Luis Alberto; Basagaña Flores, Xavier; Zumbado, Manuel; Villar García, Judit; Rius, Cristina; Mehta, Sneha; Vidal, Marta; Jiménez, Alfons; Campi, Laura; Lop Gros, Joan; Pérez Luzardo, Octavio L.; Dobaño, Carlota; Moncunill, Gemma (Elsevier, 2023)
    Background: There is wide, largely unexplained heterogeneity in immunological and clinical responses to SARS-CoV-2 infection. Numerous environmental chemicals, such as persistent organic pollutants (POPs) and chemical ...
  • Infection induced SARS-CoV-2 seroprevalence and heterogeneity of antibody responses in a general population cohort study in Catalonia Spain
    Karachaliou, Marianna; Moncunill, Gemma; Espinosa Díaz, Ana; Castaño Vinyals, Gemma; Jiménez, Alfons; Vidal, Marta; Santano, Rebeca; Barrios, Diana; Jiménez, Alfons; Puyol, Laura; Mayer, Leonie; Rubio, Rocío; O'Callaghan-Gordo, Cristina; Fossati, Serena; Rivas, Ioar; Vrijheid, Martine; Izquierdo, Luis; Aguilar, Ruth; Basagaña Flores, Xavier; García Aymerich, Judith; Dobaño, Carlota; Kogevinas, Manolis (Nature Research, 2021)
    Sparse data exist on the complex natural immunity to SARS-CoV-2 at the population level. We applied a well-validated multiplex serology test in 5000 participants of a general population study in Catalonia in blood samples ...
  • Long-term exposure to air pollution and COVID-19 vaccine antibody response in a general population cohort (COVICAT Study, Catalonia)
    Kogevinas, Manolis; Karachaliou, Marianna; Espinosa Díaz, Ana; Aguilar, Ruth; Castaño Vinyals, Gemma; García Aymerich, Judith; Rubio, Rocío; Jiménez, Alfons; Vidal, Marta; Izquierdo, Luis; Cirach, Marta; Nieuwenhuijsen, Mark J.; Dadvand, Payam; Straif, Kurt; Moncunill, Gemma; Dobaño, Carlota; Tonne, Cathryn (National Institute of Environmental Health Sciences (NIEHS), 2023)
    Background: Ambient air pollution has been associated with COVID-19 disease severity and antibody response induced by infection. Objectives: We examined the association between long-term exposure to air pollution and ...
  • Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile
    Rubio, Rocío; Aguilar, Ruth; Bustamante Pineda, Mariona; Muñoz, Erica; Vázquez-Santiago, Miquel; Santano, Rebeca; Vidal, Marta; Rodrigo Melero, Natalia; Parras, Daniel; Serra, Pau; Santamaria, Pere; Carolis, Carlo; Izquierdo, Luis; Gómez-Roig, María Dolores; Dobaño, Carlota; Moncunill, Gemma; Mazarico, Edurne (Frontiers, 2022)
    SARS-CoV-2 infected pregnant women are at increased risk of severe COVID-19 than non-pregnant women and have a higher risk of adverse pregnancy outcomes like intrauterine/fetal distress and preterm birth. However, little ...
  • Multiplex antibody analysis of IgM, IgA and IgG to SARS-CoV-2 in saliva and serum from infected children and their close contacts
    Dobaño, Carlota; Alonso, Selena; Vidal, Marta; Jiménez, Alfons; Rubio, Rocío; Santano, Rebeca; Barrios, Diana; Puyol, Laura; Baró, Bàrbara; Millat-Martínez, Pere; Ajanovic, Sara; Balanza, Núria; Arias, Sara; Rodrigo Melero, Natalia; Carolis, Carlo; Bassat, Quique; Izquierdo, Luis; Aguilar, Ruth; Moncunill, Gemma (Frontiers, 2022)
    COVID-19 affects children to a lesser extent than adults but they can still get infected and transmit SARS-CoV-2 to their contacts. Field deployable non-invasive sensitive diagnostic techniques are needed to evaluate the ...
  • Persistence and baseline determinants of seropositivity and reinfection rates in health care workers up to 12.5 months after COVID-19
    Dobaño, Carlota; Ramírez-Morros, Anna; Alonso, Selena; Vidal Alaball, Josep; Ruiz-Olalla, Gemma; Vidal, Marta; Rubio, Rocío; Cascant, Emma; Parras, Daniel; Rodrigo Melero, Natalia; Serra, Pau; Carolis, Carlo; Santamaria, Pere; Forcada, Anna; Mendioroz, Jacobo; Aguilar, Ruth; Moncunill, Gemma; Ruiz-Comellas, Anna (BioMed Central, 2021)
    We assessed the duration and baseline determinants of antibody responses to SARS-CoV-2 spike antigens and the occurrence of reinfections in a prospective cohort of 173 Spanish primary health care worker patients followed ...
  • Prepandemic personal concentrations of per- and polyfluoroalkyl substances (PFAS) and other pollutants: Specific and combined effects on the incidence of COVID-19 disease and SARS-CoV-2 infection
    Pumarega Rodríguez, José Antonio; Gasull Panadès, Magda; Koponen, Jani; Campi, Laura; Rantakokko, Panu; Henríquez Hernández, Luis Alberto; Aguilar, Ruth; Donat-Vargas, Carolina; Zumbado, Manuel; Villar García, Judit; Rius, Cristina; Santiago-Díaz, Pablo; Vidal, Marta; Jiménez Morera, Alfons; Iglesias Coma, Mar; Dobaño, Carlota; Moncunill, Gemma; Porta Serra, Miquel (Elsevier, 2023)
    Objective: To investigate the specific and combined effects of personal concentrations of some per- and polyfluoroalkyl substances (PFAS), other persistent organic pollutants (POPs), and chemical elements -measured in ...
  • RBD-Based ELISA and luminex predict Anti-SARS-CoV-2 surrogate-neutralizing activity in two longitudinal cohorts of German and Spanish health care workers
    Aguilar, Ruth; Vidal, Marta; Rubio, Rocío; Jiménez, Alfons; Carolis, Carlo; Mayor, Alfredo; Izquierdo, Luis; Garcia Basteiro, Alberto L.; Moncunill, Gemma; Dobaño, Carlota; Gerhard, Markus (American Society for Microbiology, 2023)
    The ability of antibodies to neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important correlate of protection. For routine evaluation of protection, however, a simple and cost-efficient ...
  • SARS-CoV-2 infection, vaccination, and antibody response trajectories in adults: a cohort study in Catalonia
    Karachaliou, Marianna; Moncunill, Gemma; Espinosa Díaz, Ana; Castaño Vinyals, Gemma; Rubio, Rocío; Vidal, Marta; Jiménez, Alfons; Prados, Esther; Bañuls, Marc; Melero, Natalia Rodrigo; Izquierdo, Luis; Carolis, Carlo; Goldberg, Ximena; Aguilar, Ruth; García Aymerich, Judith; Kogevinas, Manolis; Dobaño, Carlota (BioMed Central, 2022)
    Background: Heterogeneity of the population in relation to infection, COVID-19 vaccination, and host characteristics is likely reflected in the underlying SARS-CoV-2 antibody responses. Methods: We measured IgM, IgA, and ...
  • SARS-CoV-2 seroprevalence study in pediatric patients and health care workers using multiplex antibody immunoassays
    Prados de la Torre, Esther; Obando, Ignacio; Vidal, Marta; Felipe, Beatriz de; Aguilar, Ruth; Izquierdo, Luis; Carolis, Carlo; Olbrich, Peter; Capilla-Miranda, Ana; Serra, Pau; Santamaria, Pere; Blanco-Lobo, Pilar; Moncunill, Gemma; Rodríguez-Ortega, Manuel J.; Dobaño, Carlota (MDPI, 2022)
    SARS-CoV-2 infection has become a global health problem specially exacerbated with the continuous appearance of new variants. Healthcare workers (HCW) have been one of the most affected sectors. Children have also been ...
  • Seroprevalence and socioeconomic impact of the first SARS-CoV-2 infection wave in a small town in Navarre, Spain
    Ribes, Marta; Montañà, Júlia; Vidal, Marta; Aguilar, Ruth; Nicolás, Patricia; Alfonso, Uxue; Rodrigo Melero, Natalia; Carolis, Carlo; Dobaño, Carlota; Moncunill, Gemma; Chaccour, Carlos (Nature Research, 2023)
    The characterization of the antibody response to SARS-CoV-2 and its determinants are key for the understanding of COVID-19. The identification of vulnerable populations to the infection and to its socioeconomic impact is ...
  • Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses
    Ortega, Natalia; Ribes, Marta; Vidal, Marta; Rubio, Rocío; Aguilar, Ruth; Williams, Sarah; Barrios, Diana; Alonso, Selena; Mitchell, Robert A.; Jairoce, Chenjerai; Cruz, Angeline; Jimenez, Alfons; Santano, Rebeca; Méndez, Susana; Lamoglia, Montserrat; Rosell, Neus; Llupià, Anna; Puyol, Laura; Chi, Jordi; Rodrigo Melero, Natalia; Mayor, Alfredo; Vilella, Anna; Trilla, Antoni; Carolis, Carlo; Izquierdo, Luis; García-Basteiro, Alberto L.; Moncunill, Gemma; Dobaño, Carlota (Nature Research, 2021)
    Unraveling the long-term kinetics of antibodies to SARS-CoV-2 and the individual characteristics influencing it, including the impact of pre-existing antibodies to human coronaviruses causing common cold (HCoVs), is essential ...
  • Sustained seropositivity up to 20.5 months after COVID-19
    Dobaño, Carlota; Ramírez-Morros, Anna; Alonso, Selena; Rubio, Rocío; Ruiz-Olalla, Gemma; Vidal Alaball, Josep; Macià, Dídac; Miró Catalina, Queralt; Vidal, Marta; Fuster Casanovas, Aina; Prados de la Torre, Esther; Barrios, Diana; Jiménez, Alfons; Zanoncello, Jasmina; Rodrigo Melero, Natalia; Carolis, Carlo; Izquierdo, Luis; Aguilar, Ruth; Moncunill, Gemma; Ruiz-Comellas, Anna (BioMed Central, 2022)
    This study evaluated the persistence of IgM, IgA, and IgG to SARS-CoV-2 spike and nucleocapsid antigens up to 616 days since the onset of symptoms in a longitudinal cohort of 247 primary health care workers from Barcelona, ...

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