Browsing by Author "Álvarez-González, Lucía"

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  • Blastomeres of 8-cell mouse embryos differ in their ability to generate embryonic stem cells and produce lines with different transcriptional signatures
    Alonso-Alonso, Sandra; Esteve-Codina, Anna; Martín-Mur, Beatriz; Álvarez-González, Lucía; Ruiz Herrera, Aurora; Santaló, Josep; Ibáñez, Elena (Frontiers, 2023)
    Embryonic stem cell (ESC) derivation from single blastomeres of 8-cell mouse embryos results in lower derivation rates than that from whole blastocysts, raising a biological question about the developmental potential of ...
  • Principles of 3D chromosome folding and evolutionary genome reshuffling in mammals
    Álvarez-González, Lucía; Arias-Sardá, Cristina; Montes-Espuña, Laia; Marín-Gual, Laia; Vara, Covadonga; Lister, Nicholas C.; Cuartero, Yasmina; Garcia, Francisca; Deakin, Janine; Renfree, Marilyn B.; Robinson, Terence J.; Martí Renom, Marc A.; Waters, Paul D.; Farré, Marta; Ruiz Herrera, Aurora (Elsevier, 2022)
    Studying the similarities and differences in genomic interactions between species provides fertile grounds for determining the evolutionary dynamics underpinning genome function and speciation. Here, we describe the ...
  • The impact of chromosomal fusions on 3D genome folding and recombination in the germ line
    Vara, Covadonga; Paytuví Gallart, Andreu; Cuartero, Yasmina; Álvarez-González, Lucía; Marín-Gual, Laia; Garcia, Francisca; Florit-Sabater, Beatriu; Capilla, Laia; Sanchéz-Guillén, Rosa Ana; Sarrate, Zaida; Cigliano, Riccardo Aiese; Sanseverino, Walter; Searle, Jeremy B.; Ventura, Jacint; Martí Renom, Marc A.; Le Dily, François; Ruiz Herrera, Aurora (Nature Research, 2021)
    The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear. Here, we take advantage of chromosome conformation ...

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