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  • C elegans and CRISPR/Cas gene editing to study BAP1 cancer-related mutations and cisplatin chemoresistance
    Martínez Fernández, Carmen (2021-03-19)
    Model organisms and gene-editing strategies are fundamental to address a variety of scientific questions from basic science to biomedical research. Here, we reinforced the use of two powerful tools, the experimental system ...
  • C-edge loops of arrestin function as a membrane anchor
    Lally, Ciara C.M.; Bauer, Brain; Selent, Jana; Sommer, Martha E. (Nature Publishing Group, 2017)
    G-protein-coupled receptors are membrane proteins that are regulated by a small family of arrestin proteins. During formation of the arrestin–receptor complex, arrestin first interacts with the phosphorylated receptor C ...
  • C-reactive protein may misdiagnose prosthetic joint infections, particularly chronic and low-grade infections
    Pérez-Prieto, Daniel; Portillo, María Eugenia; Puig Verdié, Luís; Alier Fabrego, Albert; Martínez Díaz, Santos; Sorli Redó, M. Luisa; Horcajada Gallego, Juan Pablo; Monllau García, Juan Carlos (Springer, 2017)
    BACKGROUND: Periprosthetic tissue cultures, sonication and synovial fluid cultures remain the gold standard for prosthetic joint infection (PJI) diagnosis. However, some 15-20% culture-negative PJI are still reported. ...
  • The C-terminus of H-ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways
    Oeste, Clara L; Díez Dacal, Beatriz; Bray, Francesca; García de Lacoba, Mario; Torre, Beatriz G. de la; Andreu Martínez, David; Ruiz Sánchez, Antonio J; Pérez Inestrosa, Ezequiel; García Domínguez, Carlota A; Rojas, José M; Pérez Sala, Dolores (Public Library of Science (PLoS), 2011)
    Ras proteins are crucial players in differentiation and oncogenesis and constitute important drug targets. The localization and activity of Ras proteins are highly dependent on posttranslational modifications at their ...
  • C. El segle de les grans barbàries
    Nadal Gaya, Carlos, 1923-2010 (Universitat Pompeu Fabra, 2013)
  • C/EBPalpha activates pre-existing and de novo macrophage enhancers during induced pre-B cell transdifferentiation and myelopoiesis
    van Oevelen, Chris; Collombet, Samuel; Vicent, Guillermo Pablo; Hoogenkamp, Maarten; Lepoivre, Cyrille; Badeaux, Aimee; Bussmann, Lars; Sardina, Jose Luis; Thieffry, Denis; Beato, Miguel; Shi, Yang; Bonifer, Constanze; Graf, T. (Thomas) (Elsevier, 2015)
    Transcription-factor-induced somatic cell conversions are highly relevant for both basic and clinical research yet their mechanism is not fully understood and it is unclear whether they reflect normal differentiation ...
  • C/EBPα instructs trophectoderm and pluripotency through the II6 pathway
    Plana Carmona, Marcos (2021-04-09)
    Continuous C/EBPa expression converts B cells into macrophages while its transient upregulation before the Yamanaka factors yields highly efficient iPSC reprogramming. C/EBP members regulate Il6 pathway genes and IL-6 ...
  • C/EBPα mediates the growth inhibitory effect of progestins on breast cancer cells
    Nacht, A. Silvina; Ferrari, Roberto; Zaurín Quer, Roser; Scabia, Valentina; Carbonell-Caballero, Jose; Le Dily, François; Quilez Oliete, Javier; Leopoldi, Alexandra; Brisken, Cathrin; Beato, Miguel; Vicent, Guillermo Pablo (EMBO Press, 2019)
    Steroid hormones are key gene regulators in breast cancer cells. While estrogens stimulate cell proliferation, progestins activate a single cell cycle followed by proliferation arrest. Here, we use biochemical and genome-wide ...
  • C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells
    Di Stefano, Bruno (Universitat Pompeu Fabra, 2014-10-31)
    One of the major goals of current stem cell research is understanding the mechanism of somatic cell reprogramming by Oct4, Sox2, Klf4 and Myc (OSKM) into induced pluripotent stem cells (iPSCs). However, the finding that only ...
  • C10-HDAC7
    Barneda Zahonero, Bruna; Román González, Lidia; Collazo, Olga; Rafati, Haleh; Islam, Abul, 1978-; Bussmann, Lars; Di Tullio, Alessandro, 1982-; Andrés, Luisa De; Graf, T. (Thomas); López Bigas, Núria; Mahmoudi, Tokameh; Parra, Maribel (Universitat Pompeu Fabra, 2013-05)
    HDAC7 is a repressor of myeloid genes whose downregulation in pre-B cells is required for transdifferentiation into macrophages.
  • CAAStools: a toolbox to identify and test Convergent Amino Acid Substitutions
    Barteri, Fabio; Valenzuela, Alejandro; Farré, Xavier; Juan, David; Muntané, Gerard; Esteve Altava, Borja; Navarro i Cuartiellas, Arcadi, 1969- (Oxford University Press, 2023)
    Motivation: Coincidence of Convergent Amino Acid Substitutions (CAAS) with phenotypic convergences allow pinpointing genes and even individual mutations that are likely to be associated with trait variation within their ...
  • Cab45 is required for Ca(2+)-dependent secretory cargo sorting at the trans-Golgi network
    Blume, Julia von; Alleaume, Anne-Marie; Kienzle, Christine; Carreras Sureda, Amado, 1986-; Valverde, M. A. (Miguel Ángel), 1963-; Malhotra, Vivek (Rockefeller University Press, 2012)
    Ca(2+) import into the lumen of the trans-Golgi network (TGN) by the secretory pathway calcium ATPase1 (SPCA1) is required for the sorting of secretory cargo. How is Ca(2+) retained in the lumen of the Golgi, and what is ...
  • Cabbage and fermented vegetables: From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19
    Bousquet, Jean; Antó i Boqué, Josep Maria; Czarlewski, Wienczyslawa; Haahtela, Tari; Fonseca, Susana C.; Iaccarino, Guido; Blain, Hubert; Vidal, Alain; Sheikh, Aziz; Akdis, Cezmi A.; Zuberbier, Torsten; ARIA group (Wiley, 2020)
    Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of ...
  • ¿Caben los animales en la filosofía política de John Rawls?
    Magaña Fernández, Pablo (Instituto Tecnológico Autónomo de México, 2022)
    ¿Qué papel juegan los animales no humanos en la filosofía política de John Rawls? En este artículo identifico tres posibles respuestas. Según la respuesta integracionista, los animales pueden ser incluidos en su teoría de ...
  • CABIGO: Catálogo Bibliográfico sobre Góngora (2000-2014)
    Rojas Castro, Antonio; Pedraza Rodríguez, Amanda; Nadal, Cèlia (Biblioteca Virtual Miguel de Cervantes, 2015)
    CABIGO recoge 801 referencias bibliográficas fechadas entre 2000 y 2014 en varios idiomas. Con esta bibliografía se pretende facilitar el estudio de la obra de Luis de Góngora poniendo a disposición de cualquier interesado ...
  • Cabut/dTIEG associates with the transcription factor Yorkie for growth control
    Ruíz Romero, Marina; Blanco, Enrique; Paricio, Nuria; Serras Rigalt, Florenci; Corominas Guiu, Montserrat (EMBO Press, 2015)
    The Drosophila transcription factor Cabut/dTIEG (Cbt) is a growth regulator, whose expression is modulated by different stimuli. Here, we determine Cbt association with chromatin and identify Yorkie (Yki), the transcriptional ...
  • El CAC ho ha tornat a fer
    José i Solsona, Carles (Universitat Pompeu Fabra, 2021)
    L’estudi El CAC ho ha tornat a fer analitza la darrera verificació, corresponent a l’exercici 2019, que el Consell Audiovisual de Catalunya ha efectuat tocant a l’acompliment per part de CCMA, SA, de les obligacions de ...
  • El CAC publica l’Informe de l’audiovisual 2012-13
    Besalú Casademont, Reinald, 1983- (2014-11-21)
  • El CAC publica l’Informe de l’audiovisual 2012-13
    Besalú Casademont, Reinald, 1983- (Universitat Pompeu Fabra, 2014)
  • Caciquismo, racismo y actitudes ante el status político futuro de la isla en las provincias occidentales de Cuba, 1906-1909
    Ibarra Cuesta, Jorge (Universitat Pompeu Fabra, 1999)

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