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  • Martínez Fernández, Carmen (2021-03-19)
    Model organisms and gene-editing strategies are fundamental to address a variety of scientific questions from basic science to biomedical research. Here, we reinforced the use of two powerful tools, the experimental system ...
  • Lally, Ciara C.M.; Bauer, Brain; Selent, Jana; Sommer, Martha E. (Nature Publishing Group, 2017)
    G-protein-coupled receptors are membrane proteins that are regulated by a small family of arrestin proteins. During formation of the arrestin–receptor complex, arrestin first interacts with the phosphorylated receptor C ...
  • Pérez-Prieto, Daniel; Portillo, María Eugenia; Puig Verdié, Luís; Alier Fabrego, Albert; Martínez Díaz, Santos; Sorli Redó, M. Luisa; Horcajada Gallego, Juan Pablo; Monllau García, Juan Carlos (Springer, 2017)
    BACKGROUND: Periprosthetic tissue cultures, sonication and synovial fluid cultures remain the gold standard for prosthetic joint infection (PJI) diagnosis. However, some 15-20% culture-negative PJI are still reported. ...
  • Oeste, Clara L.; Díez Dacal, Beatriz; Bray, Francesca; García de Lacoba, Mario; Torre, Beatriz G. de la; Andreu Martínez, David; Ruiz Sánchez, Antonio J; Pérez Inestrosa, Ezequiel; García Domínguez, Carlota A; Rojas, José M; Pérez Sala, Dolores (Public Library of Science (PLoS), 2011)
    Ras proteins are crucial players in differentiation and oncogenesis and constitute important drug targets. The localization and activity of Ras proteins are highly dependent on posttranslational modifications at their ...
  • Nadal Gaya, Carlos, 1923-2010 (Universitat Pompeu Fabra, 2013)
  • van Oevelen, Chris; Collombet, Samuel; Vicent, Guillermo Pablo; Hoogenkamp, Maarten; Lepoivre, Cyrille; Badeaux, Aimee; Bussmann, Lars; Sardina, Jose Luis; Thieffry, Denis; Beato, Miguel; Shi, Yang; Bonifer, Constanze; Graf, T. (Thomas) (Elsevier, 2015)
    Transcription-factor-induced somatic cell conversions are highly relevant for both basic and clinical research yet their mechanism is not fully understood and it is unclear whether they reflect normal differentiation ...
  • Plana Carmona, Marcos (2021-04-09)
    Continuous C/EBPa expression converts B cells into macrophages while its transient upregulation before the Yamanaka factors yields highly efficient iPSC reprogramming. C/EBP members regulate Il6 pathway genes and IL-6 ...
  • Nacht, A. Silvina; Ferrari, Roberto; Zaurín Quer, Roser; Scabia, Valentina; Carbonell-Caballero, Jose; Le Dily, François; Quilez Oliete, Javier; Leopoldi, Alexandra; Brisken, Cathrin; Beato, Miguel; Vicent, Guillermo Pablo (EMBO Press, 2019)
    Steroid hormones are key gene regulators in breast cancer cells. While estrogens stimulate cell proliferation, progestins activate a single cell cycle followed by proliferation arrest. Here, we use biochemical and genome-wide ...
  • Di Stefano, Bruno (Universitat Pompeu Fabra, 2014-10-31)
    One of the major goals of current stem cell research is understanding the mechanism of somatic cell reprogramming by Oct4, Sox2, Klf4 and Myc (OSKM) into induced pluripotent stem cells (iPSCs). However, the finding that only ...
  • Barneda Zahonero, Bruna; Román González, Lidia; Collazo, Olga; Rafati, Haleh; Islam, Abul, 1978-; Bussmann, Lars; Di Tullio, Alessandro, 1982-; Andrés, Luisa De; Graf, T. (Thomas); López Bigas, Núria; Mahmoudi, Tokameh; Parra, Maribel (Universitat Pompeu Fabra, 2013-05)
    HDAC7 is a repressor of myeloid genes whose downregulation in pre-B cells is required for transdifferentiation into macrophages.
  • Barteri, Fabio; Valenzuela, Alejandro; Farré, Xavier; Juan, David; Muntané, Gerard; Esteve Altava, Borja; Navarro i Cuartiellas, Arcadi, 1969- (Oxford University Press, 2023)
    Motivation: Coincidence of Convergent Amino Acid Substitutions (CAAS) with phenotypic convergences allow pinpointing genes and even individual mutations that are likely to be associated with trait variation within their ...
  • Blume, Julia von; Alleaume, Anne-Marie; Kienzle, Christine; Carreras Sureda, Amado, 1986-; Valverde, M. A. (Miguel Ángel), 1963-; Malhotra, Vivek (Rockefeller University Press, 2012)
    Ca(2+) import into the lumen of the trans-Golgi network (TGN) by the secretory pathway calcium ATPase1 (SPCA1) is required for the sorting of secretory cargo. How is Ca(2+) retained in the lumen of the Golgi, and what is ...
  • Bousquet, Jean; Antó i Boqué, Josep Maria; Czarlewski, Wienczyslawa; Haahtela, Tari; Fonseca, Susana C.; Iaccarino, Guido; Blain, Hubert; Vidal, Alain; Sheikh, Aziz; Akdis, Cezmi A.; Zuberbier, Torsten; ARIA group (Wiley, 2020)
    Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of ...
  • Magaña Fernández, Pablo (Instituto Tecnológico Autónomo de México, 2022)
    ¿Qué papel juegan los animales no humanos en la filosofía política de John Rawls? En este artículo identifico tres posibles respuestas. Según la respuesta integracionista, los animales pueden ser incluidos en su teoría de ...
  • Rojas Castro, Antonio; Pedraza Rodríguez, Amanda; Nadal, Cèlia (Biblioteca Virtual Miguel de Cervantes, 2015)
    CABIGO recoge 801 referencias bibliográficas fechadas entre 2000 y 2014 en varios idiomas. Con esta bibliografía se pretende facilitar el estudio de la obra de Luis de Góngora poniendo a disposición de cualquier interesado ...
  • Ruíz Romero, Marina; Blanco, Enrique; Paricio, Nuria; Serras Rigalt, Florenci; Corominas Guiu, Montserrat (EMBO Press, 2015)
    The Drosophila transcription factor Cabut/dTIEG (Cbt) is a growth regulator, whose expression is modulated by different stimuli. Here, we determine Cbt association with chromatin and identify Yorkie (Yki), the transcriptional ...
  • José i Solsona, Carles (Universitat Pompeu Fabra, 2021)
    L’estudi El CAC ho ha tornat a fer analitza la darrera verificació, corresponent a l’exercici 2019, que el Consell Audiovisual de Catalunya ha efectuat tocant a l’acompliment per part de CCMA, SA, de les obligacions de ...
  • Besalú Casademont, Reinald, 1983- (2014-11-21)
  • Besalú Casademont, Reinald, 1983- (Universitat Pompeu Fabra, 2014)

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