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  • A 12-gene expression signature is associated with aggressive histological in prostate cancer: SEC14L1 and TCEB1 genes are potential markers of progression. American journal of pathology
    Agell, Laia; Hernández, Silvia; Nonell Mazelón, Lara; Lorenzo Perez, Marta; Puigdecanet Riubugent, Eulàlia; Muga, Silvia de; Juanpere, Nuria; Bermudo, Raquel; Fernández, Pedro Luís; Lorente Garin, José Antonio; Serrano Figueras, Sergi; Lloreta Trull, Josep, 1958- (Elsevier, 2012)
    The main challenge for clinical management of prostate cancer is to distinguish tumors that will progress faster and will show a higher tendency to recur from the more indolent ones. We have compared expression profiles ...
  • A 12-month study of the hikikomori syndrome of social withdrawal: Clinical characterization and different subtypes proposal
    Malagón, Angeles; Martín López, Luis Miguel; Córcoles, David; Gonzalez Fresnedo, Ana María; Bellsolà González, Magdalena; Teo, Alan R.; Pérez Solá, Victor; Bulbena Vilarrasa, Antonio; Berge Baquero, Daniel (Elsevier, 2018)
    Social withdrawal is a new mental health problem increasingly common, present in different cultures, whose psychopathology and treatment is not yet established. This study aims to determine the socio-demographic and clinical ...
  • A 3-way hybrid approach to generate a new high-quality chimpanzee reference genome (Pan_tro_3.0)
    Kuderna, Lukas F.K.; Laayouni, Hafid, 1968-; García Pérez, Raquel, 1989-; Povolotskaya, Inna, 1986-; Serres Armero, Aitor, 1992-; Gómez Garrido, Jèssica; Alioto, Tyler; Navarro i Cuartiellas, Arcadi, 1969-; Bertranpetit, Jaume, 1952-; Marquès i Bonet, Tomàs, 1975- (Oxford University Press, 2017)
    The chimpanzee is arguably the most important species for the study of human origins. A key resource for these studies is a high-quality reference genome assembly; however, as with most mammalian genomes, the current ...
  • A 3D culture system to study gene regulation in breast cancer cells
    Ramírez Cuéllar, Angélica Julieta, 1990- (2022-05-12)
    In this Thesis we report the successful growth of hormone responsive T47D cells as 3D spheroids in Matrigel mimicking the ECM. A detailed characterization by using a genome-wide approach of the main physical and biochemical ...
  • A behavioral model of adaptation
    Apesteguía, José; Ballester, Miguel A.; Cuhadaroglu, Tugce (Elsevier, 2023)
    Adaptation refers to the process of changing behavior in response to a variation in the environment. We propose a model of an adaptive individual that contemplates two forces: on the one hand the individual benefits from ...
  • A benchmark for RNA-seq quantification pipelines
    Teng, Mingxiang; Love, Michael I.; Davis, Carrie A.; Djebali, Sarah; Dobin, Alexander; Graveley, Brenton R.; Li, Sheng; Mason, Christopher E.; Olson, Sara; Pervouchine, Dmitri D.; Sloan, Cricket A.; Wei, Xintao; Zhan, Lijun; Irizarry, Rafael A. (BioMed Central, 2016)
    Obtaining RNA-seq measurements involves a complex data analytical process with a large number of competing algorithms as options. There is much debate about which of these methods provides the best approach. Unfortunately, ...
  • A benchmark of transposon insertion detection tools using real data
    Vendrell Mir, Pol; Barteri, Fabio; Merenciano, Miriam; González, Josefa; Casacuberta, Josep M.; Castanera, Raúl (BioMed Central, 2019)
    Background: Transposable elements (TEs) are an important source of genomic variability in eukaryotic genomes. Their activity impacts genome architecture and gene expression and can lead to drastic phenotypic changes. ...
  • A bi-dimensional genome scan for prolificacy traits in pigs shows the existence of multiple epistatic QTL
    Noguera, José L.; Rodríguez, Carmen; Varona, Luis; Tomàs, Anna; Muñoz, Gloria; Ramírez, Oscar; Barragán, Carmen; Arqué, Meritxell; Bidanel, Jean P.; Amills, Marcel; Ovilo, Cristina; Sánchez, Armand (BioMed Central, 2009)
    Background: Prolificacy is the most important trait influencing the reproductive efficiency of pig production systems. The low heritability and sex-limited expression of prolificacy have hindered to some extent the improvement ...
  • A Bioinformatics approach to the study of comorbidity : Insight into mental disorders
    Gutiérrez-Sacristán, Alba, 1990- (Universitat Pompeu Fabra, 2017-12-15)
    Estudios clínicos y epidemiológicos muestran que la comorbilidad, la coexistencia de varias enfermedades en un mismo paciente, tiene un gran impacto en la evolución de su estado de salud. Por lo tanto, el análisis de ...
  • A biomarker to differentiate between primary and cocaine-induced major depression in cocaine use disorder: the role of platelet IRAS/Nischarin (I1-Imidazoline Receptor)
    Keller, Benjamin; Mestre-Pintó, Juan Ignacio; Álvaro-Bartolomé, María; Martínez-Sanvisens, Diana; Farré Albaladejo, Magí; García-Fuster, M. Julia; García Sevilla, Jesús; Torrens, Marta; The NEURODEP Group (Frontiers, 2017)
    The association of cocaine use disorder (CUD) and comorbid major depressive disorder (MDD; CUD/MDD) is characterized by high prevalence and poor treatment outcomes. CUD/MDD may be primary (primary MDD) or cocaine-induced ...
  • A birth cohort study in the Middle East: the Qatari birth cohort study (QBiC) phase I
    Sadoun, Eman; Leventakou, Vasiliki; Casas Sanahuja, Maribel; Ahmed, Heba Fawzy; Kogevinas, Manolis; Fthenou, Eleni (BioMed Central, 2017)
    BACKGROUND: The latest scientific reports raise concerns about the rapidly increasing burden of chronic diseases in the state of Qatar. Pregnant Qatari women often confront complications during pregnancy including gestational ...
  • A bivalent dendrimeric peptide bearing a T-cell epitope from foot-and-mouth disease virus protein 3A improves humoral response against classical swine fever virus
    Bohórquez, José Alejandro; Defaus, Sira; Muñoz-González, Sara; Perez-Simó, Marta; Rosell, Rosa; Fraile, Lorenzo; Sobrino, Francisco; Andreu Martínez, David; Ganges, Lliliane (Elsevier, 2017)
    Three dendrimeric peptides were synthesized in order to evaluate their immunogenicity and their potential protection against classical swine fever virus (CSFV) in domestic pigs. Construct 1, an optimized version of a ...
  • A blessing or a curse: oil dependence and human capital in Nigeria
    Burkinshaw, Sarah; Indalecio González, Judith; Silberring, Jana; Simkins, Gregory (2022-06-11)
    Using all four waves of the Nigerian General Household Survey between 2011-2019, we implement a panel data model to investigate oil dependence and household human capital investment. We also supplement our analysis with a ...
  • A Bottom Up Sensor Testbed
    Almendros Díaz, Sergio (2014-12-10)
    Aquest projecte t´e com a objectiu desplegar un banc de proves de sensors que/npot ser continuat i suportat amb el suport d’una comunitat. Els sensors recullen/ndades medioambientals i est´an connectats a una xarxa de la ...
  • A bottom-up characterization of transfer functions for synthetic biology designs: lessons from enzymology
    Carbonell Ballestero, Max, 1988-; Duran Nebreda, Salvador, 1987-; Montañez, Raúl; Solé Vicente, Ricard, 1962-; Macía, Javier; Rodríguez Caso, Carlos (Oxford University Press, 2014)
    Within the field of synthetic biology, a rational design of genetic parts should include a causal understanding of their input-output responses-the so-called transfer function-and how to tune them. However, a commonly ...
  • A bounded rationality, evolutionary model for behavior in two person reciprocity games
    Prisbrey, Jeffrey E. (1993-11-01)
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  • A BPE model for the Burgers' equation
    Kohatsu, Arturo; Ogawa, Shigeyoshi (2003-10-01)
  • A brain atlas of axonal and synaptic delays based on modelling of cortico-cortical evoked potentials
    Lemaréchal, Jean-Didier; Rocamora Zúñiga, Rodrigo Alberto; F-TRACT consortium (Oxford University Press, 2022)
    Epilepsy presurgical investigation may include focal intracortical single-pulse electrical stimulations with depth electrodes, which induce cortico-cortical evoked potentials at distant sites because of white matter ...
  • A Brain Model of Disturbed Self-Appraisal in Depression
    Davey, Christopher G.; Breakspear, Michael; Pujol, Jesús; Harrison, Ben J. (American Psychiatric Association, 2017)
    OBJECTIVE: A disturbed sense of self is a core feature of depression. The medial prefrontal cortex, which has a central role in self-appraisal processes, is often implicated in the illness, although it remains unclear how ...
  • A Brief Rejoinder to Valentini
    Tan, Kok-Chor (Universitat Pompeu Fabra, 2014)