Browsing by Author "Nadal Clanchet, Eulàlia de"

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  • The rise of single-cell transcriptomics in yeast
    Nadal Ribelles, Mariona, 1984-; Solé, Carme; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Wiley, 2024)
    The field of single-cell omics has transformed our understanding of biological processes and is constantly advancing both experimentally and computationally. One of the most significant developments is the ability to measure ...
  • The Role of histone modifications in transcriptional regulation upon stress
    Viéitez Manrique, Cristina (Universitat Pompeu Fabra, 2016-05-19)
    In response to fluctuations in the environment, all living organisms have the ability to sense, respond and adapt to the new conditions. In budding yeast (Saccharomyces cerevisiae) there is a massive and rapid reorganization ...
  • The Role of the LRRC8A anion channel in adaptation to stress
    Stojakovic, Predrag (Universitat Pompeu Fabra, 2023-03-10)
    Cell volume regulation is essential for cellular homeostasis and adaptation to environmental osmotic changes. Upon hyperosmotic stress, cells need to rapidly restore osmotic balances in order to preserve the function of ...
  • The Rtg1 and Rtg3 proteins are novel transcription factors regulated by the yeast hog1 mapk upon osmotic stress
    Noriega Esteban, Núria (Universitat Pompeu Fabra, 2011-04-12)
    La adaptación de la levadura Saccharomyces cerevisiae a condiciones de alta osmolaridad está mediada por la vía de HOG ((high-osmolarity glycerol). La activación de esta vía induce una serie de respuestas que van a permitir ...
  • The zinc-finger protein Z4 cooperates with condensin II to regulate somatic chromosome pairing and 3D chromatin organization
    Puerto, Marta; Shukla, Mamta; Bujosa, Paula; Pérez Roldán, Juan; Torràs Llort, Mònica; Tamirisa, Srividya; Carbonell, Albert; Solé, Carme; Puspo, Joynob Akter; Cummings, Christopher; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc; Azorín Marín, Fernando; Rowley, M. Jordan (Oxford University Press, 2024)
    Chromosome pairing constitutes an important level of genome organization, yet the mechanisms that regulate pairing in somatic cells and the impact on 3D chromatin organization are still poorly understood. Here, we address ...
  • Timing of gene expression in a cell-fate decision system
    Aymoz, Delphine; Solé, Carme; Pierre, Jean-Jerrold; Schmitt, Marta; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc; Pelet, Serge (Wiley-Blackwell, 2018)
    During development, morphogens provide extracellular cues allowing cells to select a specific fate by inducing complex transcriptional programs. The mating pathway in budding yeast offers simplified settings to understand ...
  • Transcription factors under the control of the yeast Hog1 MAPK
    Casadomé Burriel, Laura (Universitat Pompeu Fabra, 2011-04-12)
    Yeast cells are exposed to a wide variety of environment stresses, among them changes in the osmotic conditions. An osmolar upshift leads to fast loose of intracellular water, so living cells have developed mechanisms to ...
  • Understanding retinoblastoma post-translational regulation for the design of targeted cancer therapies
    Janostiak, Radoslav; Torres-Sanchez, Ariadna; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (MDPI, 2022)
    The retinoblastoma protein (Rb1) is a prototypical tumor suppressor protein whose role was described more than 40 years ago. Together with p107 (also known as RBL1) and p130 (also known as RBL2), the Rb1 belongs to a family ...

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