The amyloid beta-peptide (Aβ) plays a leading role in Alzheimer's disease (AD) physiopathology. Even though monomeric forms of Aβ are harmless to cells, Aβ can aggregate into β-sheet oligomers and fibrils, which are both ...

Zinc is an essential micronutrient involved in many different biological processes. Zinc homeostasis is mainly regulated by 24 zinc transporters coded by the Zinc Transporter Genes (ZTGs). Notably, zinc body content is ...

The TRPV4 cation channel is expressed in a broad range of tissues where participates in the generation of a Ca2+ signal. TRPV4 participation in osmo- and mechanotransduction contributes to important functions such as ...

Zinc is an essential micronutrient with a tightly regulated systemic and cellular homeostasis. In humans, some zinc transporter genes (ZTGs) have been previously reported as candidates for strong geographically restricted ...

Zinc is an essential trace element with structural, catalytic and signaling roles in our body. At cellular level, zinc homeostasis participates in fundamental functions such as cell proliferation, migration, differentiation ...