Home
→
Browsing by Author

Browsing by Author "Torre Fornell, Rafael de la"

Now showing items 21-40 of 173

Biomarkers and cognitive function in Down syndrome : validation for phenotyping cognitive impairment

Xicota Vila, Laura (Universitat Pompeu Fabra, 2018-04-26)

Clinical trials seeking to improve cognitive performance are in dire need of biochemical biomarkers that reflect the processes taking place in the brain. In Down syndrome, this information is crucial to understand the ...
Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams-Beuren syndrome

Navarro Romero, Alba, 1990-; Galera López, Lorena, 1993-; Ortiz Romero, Paula, 1994-; Llorente-Ovejero, Alberto; Los Reyes-Ramírez, Lucía de; Bengoetxea de Tena, Iker; Garcia-Elias Heras, Anna; Mas-Stachurska, Aleksandra; Reixachs i Solé, Marina; Pastor, Antonio; Torre Fornell, Rafael de la; Maldonado, Rafael, 1961-; Benito Villabriga, Begoña; Eyras Jiménez, Eduardo; Rodríguez-Puertas, Rafael; Campuzano Uceda, María Victoria; Ozaita Mintegui, Andrés, 1969- (eLife, 2022)

Williams-Beuren syndrome (WBS) is a rare genetic multisystemic disorder characterized by mild-to-moderate intellectual disability and hypersocial phenotype, while the most life-threatening features are cardiovascular ...
Cannabinoid type-1 receptor blockade restores neurological phenotypes in two models for Down syndrome

Navarro-Romero, Alba; Vázquez-Oliver, Anna; Gomis González, Maria, 1988-; Garzón-Montesinos, Carlos; Falcón-Moya, Rafael; Pastor, Antonio; Martín García, Elena, 1975-; Pizarro Lozano, Mª Nieves; Busquets Garcia, Arnau, 1985-; Revest, Jean-Michel; Piazza, Pier Vincenzo; Bosch, Fatima; Dierssen, Mara; Torre Fornell, Rafael de la; Rodríguez-Moreno, Antonio; Maldonado, Rafael, 1961-; Ozaita Mintegui, Andrés, 1969- (Elsevier, 2019)

Intellectual disability is the most limiting hallmark of Down syndrome, for which there is no gold-standard clinical treatment yet. The endocannabinoid system is a widespread neuromodulatory system involved in multiple ...
Cannabis use induces distinctive proteomic alterations in olfactory neuroepithelial cells of schizophrenia patients

Barrera Conde, Marta; Ausín, Karina; Lachén Montes, Mercedes; Fernández Irigoyen, Joaquín; Galindo Guarín, Liliana; Cuenca Royo, Aida Ma, 1981-; Fernández Avilés, Cristina; Pérez, Victor; Torre Fornell, Rafael de la; Santamaría, Enrique; Robledo, Patricia, 1958- (MDPI, 2021)

A close epidemiological link has been reported between cannabis use and schizophrenia (SCZ). However, biochemical markers in living humans related to the impact of cannabis in this disease are still missing. Olfactory ...
Cannabis users show enhanced expression of CB1-5HT2A receptor heteromers in olfactory neuroepithelium cells

Galindo Guarín, Liliana; Moreno, Estefanía; López-Armenta, Fernando; Guinart, Dani; Cuenca Royo, Aida Ma, 1981-; Izquierdo Serra, Mercè; Xicota Vila, Laura, 1987-; Fernandez, Cristina; Menoyo Colomer, Esther; Fernández-Fernández, José Manuel, 1967-; Benítez-King, Gloria; Canela, Enric I.; Casadó, Vicent; Pérez Solá, Victor; Torre Fornell, Rafael de la; Robledo, Patricia, 1958- (Springer, 2018)

Cannabinoid CB1 receptors (CB1R) and serotonergic 2A receptors (5HT2AR) form heteromers in the brain of mice where they mediate the cognitive deficits produced by delta-9-tetrahydrocannabinol. However, it is still unknown ...
Cardioprotective effect of a virgin olive oil enriched with bioactive compounds in spontaneously hypertensive rats

Vázquez, Alejandra; Sánchez-Rodriguez, Estefanía; Vargas, Félix; Montoro-Molina, Sebastián; Romero-Cuevas, Miguel; Espejo, Juan-Antonio; Vilchez, Pedro; Jaramillo, Sara; Olmo-García, Lucía; Carrasco-Pancorbo, Alegría; Torre Fornell, Rafael de la; Fitó Colomer, Montserrat; Covas Planells, Maria Isabel; Martínez de Victoria, Emilio; Mesa, Maria-Dolores (MDPI, 2019)

Olive oil and its derivatives have been described to exert beneficial effects on hypertensive states and cardiovascular disease prevention. We studied the effects of chronic consumption of extra virgin olive oil (EVOO), ...
Cardiovascular benefits of tyrosol and its endogenous conversion into hydroxytyrosol in humans: a randomized, controlled trial

Boronat Rigol, Anna, 1990-; Mateus Rodriguez, Julian Andrés; Soldevila-Domenech, Natalia; Guerra, Mercè; Rodríguez-Morató, Jose, 1987-; Varon, Carlota; Muñoz Aguayo, Daniel; Barbosa, Francina; Morales, Juan Carlos; Gaedigk, Andreas; Langohr, Klaus; Covas Planells, Maria Isabel; Pérez Mañá, Clara; Fitó Colomer, Montserrat; Tyndale, Rachel F.; Torre Fornell, Rafael de la (Elsevier, 2019)

Introduction: The simple phenol hydroxytyrosol (OHTyr) has been associated with the beneficial health effects of extra virgin olive oil. Pre-clinical studies have identified Tyr hydroxylation, mediated by cytochrome P450 ...
CB1 cannabinoid receptors mediate cognitive deficits and structural plasticity changes during nicotine withdrawal

Saravia Santos, Rocio, 1988-; Flores de los Heros, África, 1985-; Plaza-Zabala, Ainhoa, 1982-; Busquets Garcia, Arnau, 1985-; Pastor, Antonio; Torre Fornell, Rafael de la; Di Marzo, Vicenzo; Marsicano, Giovanni; Ozaita Mintegui, Andrés, 1969-; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2017)

BACKGROUND: Tobacco withdrawal is associated with deficits in cognitive function, including attention, working memory, and episodic memory. Understanding the neurobiological mechanisms involved in these effects is crucial ...
Changes in body composition in anorexia nervosa: predictors of recovery and treatment outcome.

Agüera, Zaida; Torre Fornell, Rafael de la; Fernández Aranda, Fernando (Public Library of Science, 2015)

The restoration of body composition (BC) parameters is considered to be one of the most important goals in the treatment of patients with anorexia nervosa (AN). However, little is known about differences between AN diagnostic ...
Characterization of human gene expression changes after olive oil ingestion: an exploratory approach

Konstantinidou, Valentini; Khymenets, Olha, 1974-; Fitó Colomer, Montserrat; Torre Fornell, Rafael de la; Anglada Busquets, Roger; Dopazo, Ana; Covas Planells, Maria Isabel (Univerzita Karlova v Praze, Fakulta Socialnich Ved, 2009)

Olive oil consumption is protective against risk factors for cardiovascular and cancer diseases. A nutrigenomic approach was performed to assess whether changes in gene expression could occur in human peripheral blood ...
Clinical and toxicological significance of the involvement of the cytocrhome p450 system in the metabolism of 3,4-methylenedioxymethamphetamine

O'Mahony, Brian (Universitat Pompeu Fabra, 2011-04-12)

La 3,4-metilenodioximetanfetamina (MDMA, éxtasis) es una anfetamina sustituida de consumo frecuente y abusivo. La enzima principal que participa en el metabolismo de fase I de la MDMA, la isoforma 2D6 (CYP2D6) del citocromo ...
Clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"): the influence of gender and genetics (CYP2D6, COMT, 5-HTT)

Pardo Lozano, Ricardo; Farré Albaladejo, Magí; Yubero Lahoz, Samanta, 1985-; O'Mathuna, Brian; Torrens, Marta; Mustata, Cristina; Pérez Mañá, Clara; Langohr, Klaus; Cuyàs, Elisabet; Carbó Banús, Marcel·lí; Torre Fornell, Rafael de la (Public Library of Science (PLoS), 2012)

The synthetic psychostimulant MDMA (±3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). ...
Cognitive and neuromodulation strategies for unhealthy eating and obesity: Systematic review and discussion of neurocognitive mechanisms

Forcano, Laura; Mata, Fernanda; Torre Fornell, Rafael de la; Verdejo García, Antonio (Elsevier, 2018)

We systematically reviewed research on cognitive training and neuromodulation interventions for reducing food craving/intake, unhealthy diet and weight, and discussed their mechanisms of action. We reviewed 50 studies ...
Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors.

Viñals Álvarez, Xavier, 1985-; Moreno, Estefanía; Lanfumey, Laurence; Cordomí, Arnau; Pastor, Antonio; Torre Fornell, Rafael de la; Gasperini, Paola; Navarro, Gemma; Howell, Lesley A.; Pardo, Leonardo; Lluís, Carmen; Canela, Enric I.; McCormick, Peter J.; Maldonado, Rafael, 1961-; Robledo, Patricia, 1958- (Public Library of Science, 2015)

Activation of cannabinoid CB1 receptors (CB1R) by delta9-tetrahydrocannabinol (THC) produces a variety of negative effects with major consequences in cannabis users that constitute important drawbacks for the use of ...
Comorbilidad psiquiátrica y valores plasmáticos de 2-acilgliceroles en consumidores de alcohol en tratamiento ambulatorio. Análisis de las diferencias de género

García Marchena, Nuria; Araos, Pedro; Pavón, Francisco Javier; Ponce, Guillermo; Pedraz, María; Serrano, Antonia; Arias, Francisco; Romero Sanchiz, Pablo; Suárez, Juan; Pastor, Antonio; Torre Fornell, Rafael de la; Torrens, Marta; Rubio, Gabriel; Rodríguez de Fonseca, Fernando (Sociedad Científica Española de Estudios sobre el Alcohol, el Alcoholismo y las otras Toxicomanías, 2017)

La adicción al alcohol se asocia con una elevada comorbilidad psiquiátrica que complica el tratamiento, siendo necesaria una fenotipación clínica objetiva de estos pacientes para optimizar la atención y mejorar el pronóstico. ...
Comparative bioavailability study of a novel multi-day patch formulation of rivastigmine (twice weekly) with Exelon® transdermal patch (daily)- a randomized clinical trial

Schurad, Bjoern; Koch, Cornelius; Schug, Barbara; Morte, Adelaida; Vaqué, Anna; Torre Fornell, Rafael de la; Iniesta, Marc (Bentham Science Publishers, 2022)

Background: Rivastigmine, a reversible AChEI for symptomatic treatment of mild to moderately severe Alzheimer's dementia, is administered once daily transdermal patches, enabling an easier and continuous drug delivery. A ...
Comparison of COVID-19 and non-COVID-19 pneumonia in Down syndrome

Real de Asua, Diego; Mayer, Miguel Ángel, 1960-; Ortega, María del Carmen; Borrel, Jose M.; Bermejo, Teresa de Jesús; González Lamuño, Domingo; Manso, Coral; Moldenhauer, Fernando; Carmona Iragui, María; Hüls, Anke; Sherman, Stephanie L.; Strydom, Andre; Torre Fornell, Rafael de la; Dierssen, Mara (MDPI, 2021)

Whether the increased risk for coronavirus disease 2019 (COVID-19) hospitalization and death observed in Down syndrome (DS) are disease specific or also occur in individuals with DS and non-COVID-19 pneumonias is unknown. ...
Complementary phenol-enriched olive oil improves HDL characteristics in hypercholesterolemic subjects. A randomized, double-blind, crossover, controlled trial. The VOHF study

Farràs Mañé, Marta; Castañer, Olga; Martín-Peláez, Sandra; Hernáez, Álvaro; Schröder, Helmut, 1958-; Subirana Cachinero, Isaac; Muñoz Aguayo, Daniel; Gaixas, Sònia; Torre Fornell, Rafael de la; Farré Albaladejo, Magí; Rubió, Laura; Díaz, Oscar; Fernández-Castillejo, Sara; Solà, Rosa; Motilva, Maria-José; Fitó Colomer, Montserrat (Wiley, 2015)

Scope: Consumption of olive oil (OO) phenolic compounds (PCs) has beneficial effects on lipid profile. HDL functionality is currently considered to be a more important issue than its circulating quantity. Our aim was to ...
Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response

Fonseca Casals, Francina, 1972-; Torre Fornell, Rafael de la; Díaz, Laura; Pastor, Antonio; Cuyàs, Elisabet; Pizarro Lozano, Mª Nieves; Khymenets, Olha, 1974-; Farré Albaladejo, Magí; Torrens, Marta (Public Library of Science (PLoS), 2011)

Although the efficacy of methadone maintenance treatment (MMT) in opioid dependence disorder has been well established, the influence of methadone pharmacokinetics in dose requirement and clinical outcome remains controversial. ...
Correction: Impulsivity is longitudinally associated with healthy and unhealthy dietary patterns in individuals with overweight or obesity and metabolic syndrome within the framework of the PREDIMED-Plus trial

Gómez Martínez, Carlos; Babio, Nancy; Júlvez Calvo, Jordi; Nishi, Stephanie; Fernández Aranda, Fernando; Martínez-González, Miguel Ángel, 1957-; Cuenca-Royo, Aida; Fernández, Rebeca; Jiménez Murcia, Susana; Torre Fornell, Rafael de la; Pintó Sala, Xavier; Bloemendaal, Mirjam; Fitó Colomer, Montserrat; Corella, Dolores; Arias, Alejandro; Salas Salvadó, Jordi (BioMed Central, 2022)

Now showing items 21-40 of 173

Search DSpace

Advanced Search

Browse

All of DSpace

My Account

In collaboration with Compliant to Partaking

Browsing by Author "Torre Fornell, Rafael de la"

Browsing by Author "Torre Fornell, Rafael de la"

Search DSpace

Browse

All of DSpace

My Account