Visualitza per autoria "Sánchez Benavides, Gonzalo"

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  • Estudios normativos españoles (proyecto NEURONORMA-Plus): normas para el Wisconsin Card Sorting Test (WCST), la Figura Compleja Modificada de Taylor (FCMT) y el Ruff-Light Trail Learning Test (RULIT)
    Pérez Enríquez, Carmen; García Escobar, Greta; Florido-Santiago, Mercedes; Piqué-Candini, J.; Arrondo-Elizarána, C.; Grau-Guinea, L.; Pereira-Cutiño, B.; Manero, Rosa María; Puig-Pijoan, Albert; Peña Casanova, Jordi; Sánchez Benavides, Gonzalo (Elsevier, 2021)
    Objetivo: ell presente estudio tiene como objetivo proporcionar normas y ajustes para edad, educación y género para el Wisconsin Card Sorting Test (WCST), la Figura Compleja Modificada de Taylor (FCMT) y el Ruff-Light Trail ...
  • Exploring cognitive and biological correlates of sleep quality and their potential links with Alzheimer's disease (ALFASleep project). Protocol for an observational study
    Fauria, Karine; Minguillón, Carolina; Sánchez Benavides, Gonzalo; Arenaza Urquijo, Eider M.; Suárez-Calvet, Marc; Domingo Gispert, Juan; Grau-Rivera, Oriol (BMJ Publishing Group, 2022)
    Introduction: the growing worldwide prevalence of Alzheimer's disease (AD) and the lack of effective treatments pose a dire medical challenge. Sleep disruption is also prevalent in the ageing population and is increasingly ...
  • Genetic characterization of the ALFA study: Uncovering genetic profiles in the Alzheimer's continuum
    Vilor Tejedor, Natàlia, 1988-; Genius, Patricia; Rodríguez-Fernández, Blanca; Minguillón, Carolina; Sadeghi, Iman; González-Escalante, Armand; Crous-Bou, Marta; Suárez-Calvet, Marc; Grau-Rivera, Oriol; Brugulat Serrat, Anna, 1986-; Sánchez Benavides, Gonzalo; Esteller, Manel; Fauria, Karine; Molinuevo, José Luis; Navarro i Cuartiellas, Arcadi, 1969-; Gispert López, Juan Domingo; Alzheimer’s Disease Neuroimaging Initiative; ALFA Study (Wiley, 2023)
    Introduction: In 2013, the ALzheimer's and FAmilies (ALFA) project was established to investigate pathophysiological changes in preclinical Alzheimer's disease (AD), and to foster research on early detection and preventive ...
  • Genetically predicted telomere length and Alzheimer's disease endophenotypes: a Mendelian randomization study
    Rodríguez-Fernández, Blanca; Vilor Tejedor, Natàlia, 1988-; Arenaza Urquijo, Eider M.; Sánchez Benavides, Gonzalo; Suárez-Calvet, Marc; Operto, Grégory; Minguillón, Carolina; Navarro i Cuartiellas, Arcadi, 1969-; Gispert López, Juan Domingo; Sala Vila, Aleix; ALFA Study (BioMed Central, 2022)
    Telomere length (TL) is associated with biological aging, consequently influencing the risk of age-related diseases such as Alzheimer's disease (AD). We aimed to evaluate the potential causal role of TL in AD endophenotypes ...
  • Genotypic effects of APOE-ε4 on resting-state connectivity in cognitively intact individuals support functional brain compensation
    Cacciaglia, Raffaele; Operto, Grégory; Falcón, Carles; González de Echávarri, José Maria; Sánchez Benavides, Gonzalo; Brugulat Serrat, Anna, 1986-; Milà Alomà, Marta; Blennow, Kaj; Zetterberg, Henrik; Molinuevo, José Luis; Suárez-Calvet, Marc; Gispert López, Juan Domingo; ALFA Study (Oxford University Press, 2022)
    The investigation of resting-state functional connectivity (rsFC) in asymptomatic individuals at genetic risk for Alzheimer's disease (AD) enables discovering the earliest brain alterations in preclinical stages of the ...
  • Impact of urban environmental exposures on cognitive performance and brain structure of healthy individuals at risk for Alzheimer's dementia
    Crous-Bou, Marta; Gascon Merlos, Mireia, 1984-; Gispert López, Juan Domingo; Cirach, Marta; Sánchez Benavides, Gonzalo; Falcón, Carles; Arenaza Urquijo, Eider M.; Gotsens, Xavier; Fauria, Karine; Sunyer Deu, Jordi; Nieuwenhuijsen, Mark J.; Molinuevo, José Luis; ALFA Study (Elsevier, 2020)
    Background: Air quality might contribute to incidence of dementia-related disorders, including Alzheimer’s dementia (AD). The aim of our study is to evaluate the effect of urban environmental exposures (including exposure ...
  • Intensive assessment of executive functions derived from performance in cognitive training games
    Soldevila-Domenech, Natalia; De Toma, Ilario; Forcano, Laura; Diaz-Pellicer, Patricia; Cuenca Royo, Aida Ma, 1981-; Fagundo, Beatriz; Lorenzo, Thais; Gomis González, Maria, 1988-; Sánchez Benavides, Gonzalo; Fauria, Karine; Sastre, Carolina; Fernandez De Piérola, Íñigo; Molinuevo, José Luis; Verdejo García, Antonio; Torre Fornell, Rafael de la; PENSA Study Group (Elsevier, 2023)
    Traditional neuropsychological tests accurately describe the current cognitive state but fall short to characterize cognitive change over multiple short time periods. We present an innovative approach to remote monitoring ...
  • Long-term exposure to residential green and blue spaces and anxiety and depression in adults: A cross-sectional study
    Gascon Merlos, Mireia, 1984-; Sánchez Benavides, Gonzalo; Dadvand, Payam; Martínez, David; Gramunt Fombuena, Nina; Gotsens, Xavier; Cirach, Marta; Vert Roca, Cristina, 1991-; Molinuevo, José Luis; Crous-Bou, Marta; Nieuwenhuijsen, Mark J. (Elsevier, 2018)
    Background: Although exposure to natural outdoor environments has been consistently associated with improved perceived general health, available evidence on a protective association between this exposure and specific mental ...
  • Patterns of white matter hyperintensities associated with cognition in middle-aged cognitively healthy individuals
    Brugulat Serrat, Anna, 1986-; Salvadó, Gemma; Sudre, Carole H.; Grau-Rivera, Oriol; Suárez-Calvet, Marc; Falcón, Carles; Sánchez Benavides, Gonzalo; Gramunt Fombuena, Nina; Fauria, Karine; Cardoso, M. Jorge; Barkhof, Frederik; Molinuevo, José Luis; Gispert López, Juan Domingo; ALFA Study (Springer, 2019)
    White matter hyperintensities (WMH) are commonly detected in the brain of elderly individuals and have been associated with a negative impact on multiple cognitive domains. We aim to investigate the impact of global and ...
  • Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer's disease
    Milà Alomà, Marta; Shekari, Mahnaz; Salvadó, Gemma; Ortiz Romero, Paula, 1994-; González-Escalante, Armand; Sánchez Benavides, Gonzalo; Minguillón, Carolina; Gispert López, Juan Domingo; Suárez-Calvet, Marc; Blennow, Kaj (Nature Research, 2022)
    Blood biomarkers indicating elevated amyloid-β (Aβ) pathology in preclinical Alzheimer's disease are needed to facilitate the initial screening process of participants in disease-modifying trials. Previous biofluid data ...
  • Prepandemic alzheimer disease biomarkers and anxious-depressive symptoms during the COVID-19 confinement in cognitively unimpaired adults
    Akinci, Muge; Peña-Gómez, Cleofé; Operto, Grégory; Fuentes-Julian, Sherezade; Deulofeu, Carme; Sánchez Benavides, Gonzalo; Milà Alomà, Marta; Grau-Rivera, Oriol; Gramunt Fombuena, Nina; Navarro i Cuartiellas, Arcadi, 1969-; Minguillón, Carolina; Fauria, Karine; Suridjan, Ivonne; Kollmorgen, Gwendlyn; Bayfield, Anna; Blennow, Kaj; Zetterberg, Henrik; Molinuevo, José Luis; Suárez-Calvet, Marc; Gispert López, Juan Domingo; Arenaza-Urquijo, Eider M.; ALFA Study (Lippincott Williams & Wilkins, 2022)
    Background and objectives: Increased anxious-depressive symptomatology is observed in the preclinical stage of Alzheimer disease (AD), which may accelerate disease progression. We investigated whether β-amyloid, cortical ...
  • Quantitative informant‐ and self‐reports of subjective cognitive decline predict amyloid beta PET outcomes in cognitively unimpaired individuals independently of age and APOE ε4
    Sánchez Benavides, Gonzalo; Salvadó, Gemma; Arenaza Urquijo, Eider M.; Grau-Rivera, Oriol; Suárez-Calvet, Marc; Milà Alomà, Marta; González de Echávarri, José Maria; Minguillón, Carolina; Crous-Bou, Marta; Niñerola-Baizán, Aida; Perissinotti, Andrés; Gispert López, Juan Domingo; Molinuevo, José Luis; ALFA Study (Wiley, 2020)
    Introduction: Amyloid beta (Aβ) pathology is an Alzheimer's disease early hallmark. Here we assess the value of longitudinal self- and informant reports of cognitive decline to predict Aβ positron emission tomography (PET) ...
  • Semantic Verbal Fluency Pattern, Dementia Rating Scores and Adaptive Behavior Correlate With Plasma Aβ42 Concentrations in Down Syndrome Young Adults.
    Del Hoyo Soriano, Laura; Xicota Vila, Laura, 1987-; Sánchez Benavides, Gonzalo; Cuenca Royo, Aida Ma, 1981-; Sola Llopis, Susana de; Langohr, Klaus; Fagundo, Ana B.; Farré Albaladejo, Magí; Dierssen, Mara; Torre Fornell, Rafael de la (Frontiers, 2015)
    Down syndrome (DS) is an intellectual disability (ID) disorder in which language and specifically, verbal fluency are strongly impaired domains; nearly all adults show neuropathology of Alzheimer's disease (AD), including ...
  • Subjective cognitive decline and anxious/depressive symptoms during the COVID-19 pandemic: what is the role of stress perception, stress resilience, and β-amyloid?
    Akinci, Muge; Sánchez Benavides, Gonzalo; Brugulat Serrat, Anna, 1986-; Peña-Gómez, Cleofé; Palpatzis, Eleni; Shekari, Mahnaz; Deulofeu, Carme; Fuentes-Julian, Sherezade; Salvadó, Gemma; González de Echávarri, José Maria; Suárez-Calvet, Marc; Minguillón, Carolina; Fauria, Karine; Molinuevo, José Luis; Domingo Gispert, Juan; Grau-Rivera, Oriol; Arenaza Urquijo, Eider M.; ALFA Study (BioMed Central, 2022)
    Background: the COVID-19 pandemic may worsen the mental health of people reporting subjective cognitive decline (SCD) and therefore their clinical prognosis. We aimed to investigate the association between the intensity ...
  • The ALFA project: A research platform to identify early pathophysiological features of Alzheimer's disease
    Molinuevo, José Luis; Gramunt Fombuena, Nina; Domingo Gispert, Juan; Fauria, Karine; Esteller, Manel; Minguillón, Carolina; Sánchez Benavides, Gonzalo; Huesa, Gema; Morán, Sebastián; Dal-Ré, Rafael; Camí, Jordi, 1952- (Elsevier, 2016)
    Introduction: The preclinical phase of Alzheimer's disease (AD) is optimal for identifying early pathophysiological events and developing prevention programs, which are shared aims of the ALFA project, including the ALFA ...
  • VNTR-DAT1 and COMTVal158Met Genotypes Modulate Mental Flexibility and Adaptive Behavior Skills in Down Syndrome
    Del Hoyo Soriano, Laura; Xicota Vila, Laura, 1987-; Langohr, Klaus; Sánchez Benavides, Gonzalo; Sola Llopis, Susana de; Cuenca Royo, Aida Ma, 1981-; Rodríguez, Joan; Rodríguez-Morató, Jose, 1987-; Farré Albaladejo, Magí; Dierssen, Mara; Torre Fornell, Rafael de la; The TESDAD Study Group (Frontiers, 2016)
    Down syndrome (DS) is an aneuploidy syndrome that is caused by trisomy for human chromosome 21 resulting in a characteristic cognitive and behavioral phenotype, which includes executive functioning and adaptive behavior ...
  • White matter hyperintensities mediate gray matter volume and processing speed relationship in cognitively unimpaired participants
    Brugulat Serrat, Anna, 1986-; Salvadó, Glòria; Operto, Grégory; Cacciaglia, Raffaele; Sudre, Carole H.; Grau-Rivera, Oriol; Suárez-Calvet, Marc; Falcón, Carles; Sánchez Benavides, Gonzalo; Gramunt Fombuena, Nina; Minguillón, Carolina; Fauria, Karine; Barkhof, Frederik; Molinuevo, José Luis; Gispert López, Juan Domingo; ALFA Study (Wiley, 2020)
    White matter hyperintensities (WMH) have been extensively associated with cognitive impairment and reductions in gray matter volume (GMv) independently. This study explored whether WMH lesion volume mediates the relationship ...

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