Browsing by Author "Nonell Mazelón, Lara"

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  • miR-24-3p regulates CDX2 during intestinalization of cardiac-type epithelium in a human model of Barrett's esophagus
    Gil Gómez, Gabriel; Fassan, Mateo; Nonell Mazelón, Lara; Garrido, Marta; Climent Agustín, Marta Carmen; Anglada Busquets, Roger; Iglesias Coma, Mar; Guzzardo, Vicenza; Borga, Chiara; Grande Posa, Luís; Bolós, Carme de; Pera Roman, Manuel Ramón (Oxford University Press, 2021)
    Background: Cardiac-type epithelium has been proposed as the precursor of intestinal metaplasia in the development of Barrett's esophagus. Dysregulation of microRNAs (miRNAs) and their effects on CDX2 expression may ...
  • Reduced expansion of CD94/NKG2C + NK cells in chronic lymphocytic leukemia and CLL-like monoclonal B-cell lymphocytosis is not related to increased human cytomegalovirus seronegativity or NKG2C deletions
    Puiggros Metje, Anna Maria; Blanco Ares, Gonzalo, 1989-; Muntasell i Castellví, Aura, 1972-; Rodríguez-Rivera, María; Nonell Mazelón, Lara; Altadill, Mireia; Puigdecanet Riubugent, Eulàlia; Arnal, Magdalena; Calvo, Xavier; Gimeno Vázquez, Eva; Abella Monreal, Eugenia; Abrisqueta, Pau; Bosch José, Francesc Xavier, 1947-; Yélamos López, José; Ferrer, Ana; López-Botet, M. (Miguel); Espinet Solà, Blanca (Wiley, 2021)
    Introduction: Dysregulated NK cell-mediated immune responses contribute to tumor evasion in chronic lymphocytic leukemia (CLL), although the NK cell compartment in CLL-like monoclonal B-cell lymphocytosis (MBL) is poorly ...
  • Serum cytokine levels as predictive biomarkers of benefit from ipilimumab in small cell lung cancer
    Hardy-Werbin, Max; Rocha, Pedro P.; Arpí Llucià, Oriol; Taus García, Álvaro; Nonell Mazelón, Lara; Duran Jordà, Xavier, 1974-; Villanueva, Xavier; Joseph-Pietras, Deborah; Nolan, Luke; Danson, Sarah; Griffiths, Richard; López-Botet, Miguel; Rovira Guerín, Ana; Albanell Mestres, Joan; Ottensmeier, Christian; Arriola Aperribay, Edurne (Taylor & Francis, 2019)
    Background. Immunotherapy has shown efficacy in small cell lung cancer (SCLC), but only a subset of patients benefits. Surrogate biomarkers are urgently needed. Our aim was to evaluate serum Th1, Th2, and proinflammatory ...
  • SPOP and CHD1 alterations in prostate cancer: Relationship with PTEN loss, tumor grade, perineural infiltration, and PSA recurrence
    Hernández Llodrà, Silvia; Segalés Tañà, Laura, 1994-; Juanpere, Nuria; Lorenzo, Marta; Salido Galeote, Marta; Nonell Mazelón, Lara; López, David; Rodríguez-Vida, Alejo; Bellmunt Molins, Joaquim, 1959-; Fumadó Ciutat, Lluis; Cecchini Rosell, Lluís; Lloreta Trull, Josep, 1958- (Wiley, 2021)
    Background: In the non-ETS fusion of prostate cancer (PCa) pathway, SPOP mutations emerge as a distinct oncogenic driver subclass. Both SPOP downregulation and mutation can lead to SPOP target stabilization promoting ...
  • Transcriptome analysis of severely active chronic spontaneous urticaria shows an overall immunological skin involvement
    Giménez Arnau, Anna Maria; Curto Barredo, Laia; Nonell Mazelón, Lara; Puigdecanet Riubugent, Eulàlia; Yélamos López, José; Gimeno Martínez, Ramón; Rüberg, Silvia; Santamaría-Babí, Luis Francisco; Pujol Vallverdú, Ramon Maria (Wiley, 2017)
    BACKGROUND: The knowledge about chronic spontaneous urticaria (CSU) phenotypes is based on its clinical characteristics, associated comorbidities, course of the disease, and its response to the available effective drugs. ...