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Browsing by Author "Barreiro Portela, Esther"
Now showing items 21-40 of 107
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Wang, Xuejie; Villa, Carmen; Dobarganes, Yadira; Olveira, Casilda; Girón, Rosa; García-Clemente, Marta; Máiz, Luis; Sibila, Oriol; Golpe, Rafael; Menéndez, Rosario; Rodríguez-López, Juan; Prados, Concepción; Martínez-García, Miguel Ángel; Rodriguez, Juan Luis; Rosa, David de la; Duran, Xavier; Barreiro Portela, Esther (MDPI, 2021)We hypothesized that systemic inflammatory and nutritional parameters may differ between male and female patients with non-CF bronchiectasis. In a large patient cohort from the Spanish Online Bronchiectasis Registry (RIBRON), ...
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Busquets, Silvia; Pérez-Peiró, Maria; Salazar Degracia, Anna; Argilés, Josep M.; Serpe, Roberto; Rojano-Toimil, Alba; López Soriano, Francisco J.; Barreiro Portela, Esther (Wiley, 2020)Muscle wasting is associated with chronic diseases and cancer. Elucidation of the biological mechanism involved in the process of muscle mass loss and cachexia may help identify therapeutic targets. We hypothesized that ...
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Sancho Muñoz, Antonio (Universitat Pompeu Fabra, 2023-04-21)Se ha estudiado el potencial de regeneración muscular en pacientes EPOC con y sin sarcopenia. También se ha investigado otro mecanismo de regeneración muscular mediante el análisis del estrés a nivel de retículo endoplasmático ...
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Mañas García, Laura, 1991- (2021-03-05)La atrofia muscular por desuso en el contexto de las enfermedades crónicas, como enfermedades respiratorias, cáncer o un reposo prolongado, se caracteriza por la pérdida de masa y función muscular. Además, el desgaste ...
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Puig Vilanova, Ester, 1987-; Ausín Herrero, Pilar, 1974-; Martínez-Llorens, Juana Mª; Gea Guiral, Joaquim; Barreiro Portela, Esther (Public Library of Science (PLoS), 2014)Muscle dysfunction is a major comorbidity in Chronic Obstructive Pulmonary Disease (COPD). Several biological mechanisms including epigenetic events regulate muscle mass and function in models of muscle atrophy. Investigations ...
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Qin, Liyun; Guitart, Maria; Admetlló Papiol, Mireia; Esteban-Cucó, Sandra; Maiques LLacer, José María; Xia, Yingchen; Zha, Jianhua; Carbullanca Toledo, Santiago; Duran, Xavier; Wang, Xuejie; Barreiro Portela, Esther (MDPI, 2021)We hypothesized that in mild bronchiectasis patients, increased systemic inflammation and redox imbalance may take place and correlate with clinical parameters. In plasma samples from patients with very mild bronchiectasis, ...
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Pérez-Rial, Sandra; Barreiro Portela, Esther; Fernández Aceñero, María Jesús; Fernández-Valle, María Encarnación; González-Mangado, Nicolás; Peces-Barba, Germán (Public Library of Science (PLoS), 2020)Skeletal muscle dysfunction is a common complication and an important prognostic factor in patients with chronic obstructive pulmonary disease (COPD). It is associated with intrinsic muscular abnormalities of the lower ...
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Salazar Degracia, Anna; Busquets, Silvia; Argilés, Josep M.; Bargalló-Gispert, Núria; López Soriano, Francisco J.; Barreiro Portela, Esther (Elsevier, 2018)Muscle mass loss and wasting are characteristic features of patients with chronic conditions including cancer. Beta-adrenoceptors attenuate muscle wasting. We hypothesized that specific muscle atrophy signaling pathways ...
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Barreiro Portela, Esther; Salazar Degracia, Anna; Sancho Muñoz, Antonio; Aguiló Espases, Rafael; Rodríguez-Fuster, Alberto; Gea Guiral, Joaquim (American Physiological Society, 2019)Respiratory muscle dysfunction is common in patients with chronic obstructive pulmonary disease (COPD). Chronic contractile activity induces endoplasmic reticulum (ER) stress and unfolded protein response (UPR) in animals ...
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Barreiro Portela, Esther; Salazar Degracia, Anna; Sancho Muñoz, Antonio; Gea Guiral, Joaquim (Wiley, 2019)mpaired muscle strength and mass (sarcopenia) are common in patients with respiratory cachexia, namely chronic obstructive pulmonary disease (COPD) and in lung cancer (LC)-cachexia. Misfolded/unfolded proteins in endoplasmic ...
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Barreiro Portela, Esther; Tajbakhsh, Shahragim (Springer, 2017)In eukaryote cells, chromatin appears in several forms and is composed of genomic DNA, protein and RNA. The protein content of chromatin is composed primarily of core histones that are packaged into nucleosomes resulting ...
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Laveneziana, Pierantonio; Barreiro Portela, Esther; Gea Guiral, Joaquim; Verges, Samuel (European Respiratory Society, 2019)Assessing respiratory mechanics and muscle function is critical for both clinical practice and research purposes. Several methodological developments over the past two decades have enhanced our understanding of respiratory ...
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Penedo Vázquez, Antonio, 1994- (2021-11-26)La caquexia es un síndrome metabólico complejo asociado con enfermedades crónicas como el cáncer, se caracteriza por una atrofia progresiva del músculo esquelético que conduce a una disminución del peso corporal, inicia ...
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Kritikaki, Efpraxia; Asterling, Rhiannon; Ward, Lesley; Padget, Kay; Barreiro Portela, Esther; Simoes, Davina C.M. (MDPI, 2021)Exercise training promotes muscle adaptation and remodelling by balancing the processes of anabolism and catabolism; however, the mechanisms by which exercise delays accelerated muscle wasting are not fully understood. ...
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Font-Ribera, Laia; Barreiro Portela, Esther; Gracia Lavedan, Esther; Arjona, Lourdes; De Bont, Jeroen, 1989-; Tarès, Lluïsa; Vineis, Paolo; Kogevinas, Manolis; Villanueva Belmonte, Cristina (Elsevier, 2019)BACKGROUND: Swimming in pools is a healthy activity that entails exposure to disinfection by-products (DBPs), some of which are irritant and genotoxic. OBJECTIVES: We evaluated exposure to DBPs during swimming in a chlorinated ...
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Salazar Degracia, Anna; Busquets, Silvia; Argilés, Josep M.; López Soriano, Francisco J.; Barreiro Portela, Esther (PeerJ Inc., 2017)Muscle mass loss and wasting are characteristic features of patients with chronic conditions including cancer. Therapeutic options are still scarce. We hypothesized that cachexia-induced muscle oxidative stress may be ...
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Ramis Cabrer, Daniel, 1993- (Universitat Pompeu Fabra, 2019-07-11)Se ha establecido que un subconjunto de pacientes con cáncer debuta con infiltrados inmunes que se organizan en agregados en el nicho tumoral y sus alrededores. Estas estructuras linfoides se desarrollan en respuesta ...
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Vizcaya Fernández, David; Mirabelli, Maria C.; Orriols, Ramon; Antó i Boqué, Josep Maria; Barreiro Portela, Esther; Burgos, Felip; Arjona, Lourdes; Gómez, Federico P.; Zock, Jan-Paul (Elsevier, 2013)OBJECTIVES: Cleaning workers have an increased risk of asthma but the underlying mechanisms are largely unknown. We studied functional and biological characteristics in asthmatic cleaners and compared these to healthy ...
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Xia, Yingchen; Zha, Jianhua; Curull Serrano, Víctor; Sánchez-Font, Albert; Guitart, Maria; Rodríguez-Fuster, Alberto; Aguiló Espases, Rafael; Barreiro Portela, Esther (European Respiratory Society, 2022)Epithelial-mesenchymal transition (EMT) is involved in the pathophysiology of lung cancer (LC) and COPD, and the latter is an important risk factor for LC. We hypothesised that the EMT gene expression profile and signalling ...
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Barreiro Portela, Esther; Bustamante, Víctor; Cejudo, Pilar; Gáldiz, Juan B.; Gea Guiral, Joaquim; Lucas, Pilar de; Martínez-Llorens, Juana Mª; Ortega, Francesc; Puente-Maestu, Luis; Roca, Josep; Rodríguez-González Moro, José Miguel (Elsevier, 2015)In patients with chronic obstructive pulmonary disease (COPD), skeletal muscle dysfunction is a major comorbidity that negatively impacts their exercise capacity and quality of life. In the current guidelines, the most ...
Now showing items 21-40 of 107
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